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Multicomponent lipid mixtures exhibit complex phase behavior, including coexistence of nanoscopic fluid phases in ternary mixtures mimicking the composition of the outer leaflet of mammalian plasma membrane. The physical mechanisms…

软凝聚态物质 · 物理学 2011-06-01 Frederick A. Heberle , Gerald W. Feigenson

An experimental strategy has been developed specifically for the study of composition-dependent phase behavior in multi-component artificial membranes. The strategy is based on steady-state measurements of fluorescence resonance energy…

软凝聚态物质 · 物理学 2007-08-14 Jeffrey T. Buboltz

FRET measurements can provide dynamic spatial information on length scales smaller than the diffraction limit of light. Several methods exist to measure FRET between fluorophores, including Fluorescence Lifetime Imaging Microscopy (FLIM),…

定量方法 · 定量生物学 2017-01-09 Bryan Kaye , Peter J. Foster , Tae Yeon Yoo , Daniel J. Needleman

For some time now, we have been using a FRET-based strategy to make high-resolution studies of phase behavior in ternary lipid-raft membrane mixtures. Our FRET experiments can be carried out on ordinary, polydisperse multilamellar vesicle…

生物物理 · 物理学 2007-08-14 Jeffrey T. Buboltz , Charles Bwalya , Krystle Williams , Matthew Schutzer

Fluorescence resonance energy transfer (FRET) from individual, dye-labeled RNA molecules confined in freely-diffusing attoliter-volume aqueous droplets is carefully compared to FRET from unconfined RNA in solution. The use of…

生物物理 · 物理学 2015-05-21 Sheema Rahmanseresht , Peker Milas , Kieran P. Ramos , Ben D. Gamari , Lori S. Goldner

We study non-parametric frequency-domain system identification from a finite-sample perspective. We assume an open loop scenario where the excitation input is periodic and consider the Empirical Transfer Function Estimate (ETFE), where the…

系统与控制 · 电气工程与系统科学 2024-09-06 Anastasios Tsiamis , Mohamed Abdalmoaty , Roy S. Smith , John Lygeros

FRET experiments can yield state-specific structural information on complex dynamic biomolecular assemblies. However, FRET experiments need to be combined with computer simulations to overcome their sparsity. We introduce (i) an automated…

For more than ten years now, many efforts have been done to identify and characterize nature of obstructed diffusion in model and cellular lipid membranes. Amongst all the techniques developed for this purpose, FCS, by means of…

定量方法 · 定量生物学 2010-05-04 C. Favard , J. Ehrig , J. Wenger , P. -F. Lenne , H. Rigneault

We report an essential improvement of the plain Fourier Monte Carlo algorithm that promises to be a powerful tool for investigating critical behavior in a large class of lattice models, in particular those containing microscopic or…

统计力学 · 物理学 2015-02-17 Andreas Tröster

Two different metrics are used to assess Forster resonance energy transfer (FRET) between fluorophores in the steady state: (1) acceptor-quenching of donor fluorescence, E (a.k.a. transfer efficiency); and (ii) donor-excited acceptor…

化学物理 · 物理学 2009-11-13 Jeffrey T. Buboltz , Charles Bwalya , Santiago Reyes , Dobromir Kamburov

In the literature about field emission, finite elements and finite differences techniques are being increasingly employed to understand the local field enhancement factor (FEF) via numerical simulations. In theoretical analyses, it is usual…

计算物理 · 物理学 2023-05-03 Thiago A. de Assis , Fernando F. Dall'Agnol

The phase field model is a widely used mathematical approach for describing crack propagation in continuum damage fractures. In the context of phase field fracture simulations, adaptive finite element methods (AFEM) are often employed to…

数值分析 · 数学 2025-05-30 Tian Tian , Chen Chunyu , He Liang , Wei Huayi

Diffusion models produce high quality images but inference is costly due to many denoising steps and heavy matrix operations. We present DiffPro, a post-training, hardware-faithful framework that works with the exact integer kernels used in…

机器学习 · 计算机科学 2025-11-17 Farhana Amin , Sabiha Afroz , Kanchon Gharami , Mona Moghadampanah , Dimitrios S. Nikolopoulos

Membrane phase-separation is a mechanism that biological membranes often use to locally concentrate specific lipid species in order to organize diverse membrane processes. Phase separation has also been explored as a tool for the design of…

计算物理 · 物理学 2020-06-26 Alexander Zhiliakov , Yifei Wang , Annalisa Quaini , Maxim Olshanskii , Sheereen Majd

Multisine excitations are widely used for identifying multi-input multi-output systems due to their periodicity, data compression properties, and control over the input spectrum. Despite their popularity, the finite sample statistical…

统计方法学 · 统计学 2025-11-03 Rodrigo A. González , Koen Classens , Cristian R. Rojas , Tom Oomen , Håkan Hjalmarsson

In order to measure the radial displacements of facets on surface of a growing spherical Cu_{2-\delta}Se crystal with sub-nanometer resolution, we have investigated the reliability and accuracy of standard method of Fourier analysis of…

光学 · 物理学 2009-11-13 Jadranko Gladic , Zlatko Vucic , Davorin Lovric

We study the coarsening of strongly microphase separated membrane domains in the presence of recycling of material. We study the dynamics of the domain size distribution under both scale-free and size-dependent recycling. Closed form…

亚细胞过程 · 定量生物学 2018-05-11 S. Alex Rautu , G. Rowlands , M. S. Turner

In this work we propose an efficient and accurate multi-scale optical simulation algorithm by applying a numerical version of slowly varying envelope approximation in FEM. Specifically, we employ the fast iterative method to quickly compute…

光学 · 物理学 2024-12-03 Fan Xiao , Jingwei Wang , Zhongfei Xiong , Yuntian Chen

Reservoir simulators utilize numerical techniques to solve the governing equations of fluid flow in porous media and they are essential tool for oil and gas fields development. In practical reservoir simulation, the finite difference method…

流体动力学 · 物理学 2023-11-14 Taofik H. Nassan , Mohd Amro
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