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As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

种群与进化 · 定量生物学 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

We present the first fixed-parameter algorithm for constructing a tree-child phylogenetic network that displays an arbitrary number of binary input trees and has the minimum number of reticulations among all such networks. The algorithm…

离散数学 · 计算机科学 2019-07-22 Leo van Iersel , Remie Janssen , Mark Jones , Yukihiro Murakami , Norbert Zeh

The evolutionary relationships among organisms have traditionally been represented using rooted phylogenetic trees. However, due to reticulate processes such as hybridization or lateral gene transfer, evolution cannot always be adequately…

种群与进化 · 定量生物学 2022-01-20 Sungsik Kong , Joan Carles Pons , Laura Kubatko , Kristina Wicke

Comparative analyses of phylogenetic trees typically require identical taxon sets, however, in practice, trees often include distinct but overlapping taxa. Pruning non-shared leaves discards phylogenetic signal, whereas tree completion can…

种群与进化 · 定量生物学 2026-04-28 Aleksandr Koshkarov , Nadia Tahiri

Sequence comparison and alignment has had an enormous impact on our understanding of evolution, biology, and disease. Comparison and alignment of biological networks will likely have a similar impact. Existing network alignments use…

分子网络 · 定量生物学 2009-10-08 Oleksii Kuchaiev , Tijana Milenkovic , Vesna Memisevic , Wayne Hayes , Natasa Przulj

Biological systems are driven by intricate interactions among the complex array of molecules that comprise the cell. Many methods have been developed to reconstruct network models of those interactions. These methods often draw on large…

分子网络 · 定量生物学 2018-06-29 Marieke Lydia Kuijjer , Matthew Tung , GuoCheng Yuan , John Quackenbush , Kimberly Glass

Normal networks are an important class of phylogenetic networks that have compelling mathematical properties which align with intuition about inference from genetic data. While tools enabling widespread use of phylogenetic networks in the…

组合数学 · 数学 2025-12-16 Andrew Francis , Charles Semple

Phylogenetic networks extend phylogenetic trees to allow for modeling reticulate evolutionary processes such as hybridization. They take the shape of a rooted, directed, acyclic graph, and when parameterized with evolutionary parameters,…

种群与进化 · 定量生物学 2018-08-28 R. A. L. Elworth , H. A. Ogilvie , J. Zhu , L. Nakhleh

Reconstructing weighted networks from partial information is necessary in many important circumstances, e.g. for a correct estimation of systemic risk. It has been shown that, in order to achieve an accurate reconstruction, it is crucial to…

物理与社会 · 物理学 2017-03-07 Tiziano Squartini , Giulio Cimini , Andrea Gabrielli , Diego Garlaschelli

The presence of reticulate evolutionary events in phylogenies turn phylogenetic trees into phylogenetic networks. These events imply in particular that there may exist multiple evolutionary paths from a non-extant species to an extant one,…

种群与进化 · 定量生物学 2008-03-21 Gabriel Cardona , Merce Llabres , Francesc Rossello , Gabriel Valiente

Numerous methods and pipelines have recently emerged for the automatic extraction of knowledge graphs from documents such as scientific publications and patents. However, adapting these methods to incorporate alternative text sources like…

A phylogenetic network is a graph-theoretical tool that is used by biologists to represent the evolutionary history of a collection of species. One potential way of constructing such networks is via a distance-based approach, where one is…

组合数学 · 数学 2020-06-15 Leo van Iersel , Vincent Moulton , Yukihiro Murakami

In this paper, we present our first proposal of a machine learning system for the classification of freshwater snails of the genus Radomaniola. We elaborate on the specific challenges encountered during system design, and how we tackled…

计算机视觉与模式识别 · 计算机科学 2024-07-31 Dennis Vetter , Muhammad Ahsan , Diana Delicado , Thomas A. Neubauer , Thomas Wilke , Gemma Roig

Phylogenetic networks are important for the study of evolution. The number of methods to find such networks is increasing, but most such methods can only reconstruct small networks. To find bigger networks, one can attempt to combine small…

离散数学 · 计算机科学 2019-12-10 Remie Janssen , Mark Jones , Yukihiro Murakami

In this paper, we introduce a convolutional network which we call MultiPodNet consisting of a combination of two or more convolutional networks which process the input image in parallel to achieve the same goal. Output feature maps of…

计算机视觉与模式识别 · 计算机科学 2022-10-04 Hongyi Pan , Salih Atici , Ahmet Enis Cetin

The discovery of nucleic acids and the structure of DNA have brought considerable advances in the understanding of life. The development of next-generation sequencing technologies has led to a large-scale generation of data, for which…

分子网络 · 定量生物学 2022-03-30 Murilo Montanini Breve , Matheus Henrique Pimenta-Zanon , Fabrício Martins Lopes

The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing…

生物物理 · 物理学 2015-05-14 Cesar A. Hidalgo , Nicholas Blumm , Albert-Laszlo Barabasi , Nicholas Christakis

One strategy for reconstruction of phylogenetic networks is to solve the phylogenetic network problem, which involves inferring phylogenetic trees first and subsequently computing the smallest phylogenetic network that displays all the…

组合数学 · 数学 2023-09-26 Laurent Bulteau , Louxin Zhang

Since the advent of modern bioinformatics, the challenging, multifaceted problem of reconstructing phylogenetic history from biological sequences has hatched perennial statistical and algorithmic innovation. Studies of the phylogenetic…

数据结构与算法 · 计算机科学 2024-03-05 Matthew Andres Moreno , Santiago Rodriguez Papa , Emily Dolson

This work considers a new task in geometric deep learning: generating a triangulation among a set of points in 3D space. We present PointTriNet, a differentiable and scalable approach enabling point set triangulation as a layer in 3D…

计算机视觉与模式识别 · 计算机科学 2020-07-24 Nicholas Sharp , Maks Ovsjanikov