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Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

神经元与认知 · 定量生物学 2021-04-06 Annika Hagemann , Jens Wilting , Bita Samimizad , Florian Mormann , Viola Priesemann

The dynamics underlying epileptic seizures are well understood. We present a novel analysis of seizure-like events (SLEs) in an \textit{ex vivo} whole hippocampus, as well as a modeling study that sheds light on the underlying network…

生物物理 · 物理学 2007-05-23 Benjamin H. Singer , Miron Derchansky , Peter L. Carlen , Michal Zochowski

Epilepsy is one of the most prevalent neurological conditions, where an epileptic seizure is a transient occurrence due to abnormal, excessive and synchronous activity in the brain. Electroencephalogram signals emanating from the brain may…

神经元与认知 · 定量生物学 2023-12-05 Paul Grant , Md Zahidul Islam

Epilepsy is one of the most common neurological disorders globally, affecting millions of individuals. Despite significant advancements, the precise mechanisms underlying this condition remain largely unknown, making accurately predicting…

系统与控制 · 电气工程与系统科学 2024-04-05 Yuzhen Qin , Ahmed El-Gazzar , Danielle S. Bassett , Fabio Pasqualetti , Marcel van Gerven

Background and Objectives: Many biological processes are modulated by rhythms on circadian and multidien timescales. In focal epilepsy, various seizure features, such as spread and duration, can change from one seizure to the next within…

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

神经元与认知 · 定量生物学 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Critical dynamics are assumed to be an attractive mode for normal brain functioning as information processing and computational capabilities are found to be optimized there. Recent experimental observations of neuronal activity patterns…

神经元与认知 · 定量生物学 2015-05-28 Christian Meisel , Alexander Storch , Susanne Hallmeyer-Elgner , Ed Bullmore , Thilo Gross

Temporal lobe epilepsy is one of the most common chronic neurological disorder characterized by the occurrence of spontaneous recurrent seizures which can be observed at the level of populations through electroencephalogram (EEG)…

动力系统 · 数学 2009-07-17 Jonathan Touboul , Olivier Faugeras

We investigate assortativity of functional brain networks before, during, and after one-hundred epileptic seizures with different anatomical onset locations. We construct binary functional networks from multi-channel electroencephalographic…

数据分析、统计与概率 · 物理学 2013-09-24 Stephan Bialonski , Klaus Lehnertz

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

The use of EEG signal to diagnose several brain abnormalities is well-established in the literature. Particularly, epileptic seizure can be detected using EEG signals and several works were done in this field. The joint time-frequency…

信号处理 · 电气工程与系统科学 2020-01-24 Abdullah Othman , Mohamed A. Deriche

The concept of universality proposes that dynamical systems with the same power law behaviors are equivalent at large scales. We test this hypothesis on the Earth's crust and the epileptic brain, and discover that power laws also govern the…

生物物理 · 物理学 2007-12-27 Ivan Osorio , Mark G. Frei , Didier Sornette , John Milton , Ying-Cheng Lai

To define the neural networks responsible of the epileptic seizure, we had to study the electrophysiological signal in a proper way. The early recognition of the seizure build up could also be defined through the time space mapping of the…

信号处理 · 电气工程与系统科学 2019-11-19 Ridha Jarray , Nawel Jmail , Abir Hadriche , Tarek Frikha , Chokri Ben Amar

The underlying dynamics for the electroencephalographic (EEG) recordings from humans but especially epilepsy patients are usually not completely known. However, the ictal activity is claimed to be characterized by synchronous oscillations…

生物物理 · 物理学 2010-08-09 Caglar Tuncay

Inferring strength and direction of interactions from electroencephalographic (EEG) recordings is of crucial importance to improve our understanding of dynamical interdependencies underlying various physiologic and pathophysiologic…

神经元与认知 · 定量生物学 2016-10-07 Klaus Lehnertz , Henning Dickten

In this paper, we propose a time-series stochastic model based on a scale mixture distribution with Markov transitions to detect epileptic seizures in electroencephalography (EEG). In the proposed model, an EEG signal at each time point is…

信号处理 · 电气工程与系统科学 2021-11-15 Akira Furui , Tomoyuki Akiyama , Toshio Tsuji

Real time seizure detection is a fundamental problem in computational neuroscience towards diagnosis and treatment's improvement of epileptic disease. We propose a real-time computational method for tracking and detection of epileptic…

定量方法 · 定量生物学 2024-06-17 Ximena Fernández , Diego Mateos

Peaks signify important events in a signal. In a pair of signals how peaks are occurring with mutual correspondence may offer us significant insights into the mutual interdependence between the two signals based on important events. In this…

统计方法学 · 统计学 2015-01-15 Rahul Biswas , Koulik Khamaru , Kaushik Majumdar

Medically uncontrolled epileptic seizures affect nearly 15 million people worldwide, resulting in enormous economic and psychological burdens. Treatment of medically refractory epilepsy is essential for patients to achieve remission,…

定量方法 · 定量生物学 2025-12-25 Yaoyue Wang , Arian Ashourvan , Guilherme Ramos , Paul Bogdan , Emily Pereira

In many realistic networks, the edges representing the interactions between the nodes are time-varying. There is growing evidence that the complex network that models the dynamics of the human brain has time-varying interconnections, i.e.,…

神经元与认知 · 定量生物学 2016-11-29 G Manjunath