相关论文: On spatial and temporal multilevel dynamics and sc…
Creating a quantitative theory for the cortex presents challenges and raises questions. What are the significant scales--micro, meso, or macroscopic? What are the interactions--pairwise, higher order, or mean-field? And what control…
Purpose: Research into epileptic networks has recently allowed deeper insights into the epileptic process. Here we investigated the importance of individual network nodes for seizure dynamics. Methods: We analysed intracranial…
Understanding how the brain switches from normal activity to an epileptic seizure is essential for improving seizure therapy, yet the underlying mechanisms remain largely unknown. In particular, seizure onset can be described as a critical…
This chapter first presents a rather personal view of some different aspects of predictability, going in crescendo from simple linear systems to high-dimensional nonlinear systems with stochastic forcing, which exhibit emergent properties…
Temporal correlations in the brain are thought to have very dichotomic roles. On one hand they are ubiquitously present in the healthy brain and are thought to underlie feature binding during information processing. On the other hand large…
It is well known that the addition of noise in a multistable system can induce random transitions between stable states. The rate of transition can be characterised in terms of the noise-free system's dynamics and the added noise: for…
Epilepsy which is characterized by seizures is studied using EEG signals by recording the electrical activity of the brain. Different types of communication between different parts of the brain are characterized by many state of the art…
Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…
This review provides a dynamical systems perspective on psychiatric symptoms and disease, and discusses its potential implications for diagnosis, prognosis, and treatment. After a brief introduction into the theory of dynamical systems, we…
Chimera states---the coexistence of synchrony and asynchrony in a nonlocally-coupled network of identical oscillators---are often used as a model framework for epileptic seizures. Here, we explore the dynamics of chimera states in a network…
Epilepsy is a well-known neuronal disorder that can be identified by interpretation of the electroencephalogram (EEG) signal. Usually, the length of an EEG signal is quite long which is challenging to interpret manually. In this work, we…
In clinical neuroscience, epileptic seizures have been associated with the sudden emergence of coupled activity across the brain. The resulting functional networks - in which edges indicate strong enough coupling between brain regions - are…
One of epileptology's fundamental aims is the formulation of a universal, internally consistent seizure definition. To assess this aim's feasibility, three signal analysis methods were applied to a seizure time series and performance…
Seizure and synchronization are related to each other in complex manner. Altered synchrony has been implicated in loss of consciousness during partial seizures. However, the mechanism of altered consciousness following termination of…
The electroencephalographic (EEG) data intracerebrally recorded from 20 epileptic humans with different brain origins of focal epilepsies or types of seizures, ages and sexes are investigated (nearly 700 million data). Multi channel…
Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that…
Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…
Epileptic biomarkers play a crucial role in identifying the origin of seizures, an essential aspect of pre-surgical planning for epilepsy treatment. These biomarkers can vary significantly over time. By studying these temporal fluctuations,…
We propose a novel Coupled Hidden Markov Model to detect epileptic seizures in multichannel electroencephalography (EEG) data. Our model defines a network of seizure propagation paths to capture both the temporal and spatial evolution of…
Electroencephalography (EEG), as the most common tool for epileptic seizure classification, contains useful information about different physiological states of the brain. Seizure related features in EEG signals can be better identified when…