相关论文: A congestion model for cell migration
Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues.…
The simplest model of a smart spatial redistribution of individuals is proposed. A single-species population is considered, to be composed of two discrete subpopulations inhabiting two stations; migration is a transfer between them. The…
We analyze a macroscopic model with a maximal density constraint which describes short range repulsion in biological systems. This system aims at modeling finite-size particles which cannot overlap and repel each other when they are too…
Many natural and industrial processes rely on constrained transport, such as proteins moving through cells, particles confined in nanocomposite materials or gels, individuals in highly dense collec- tives and vehicular traffic conditions.…
The capability of cells to form surface extensions to non-locally probe the surrounding environment plays a key role in cell migration. The existing mathematical models for migration of cell populations driven by this non-local form of…
Adherent cells have long been known to display two modes during migration: a faster mode that is persistent in direction and a slower one where they turn. Compared to the persistent mode, the turns are less studied. Here we develop a simple…
The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…
We propose a novel mechanism of cell motility, which relies on the coupling of actin polymerization at the cell membrane to geometric confinement. We consider a polymerizing viscoelastic cytoskeletal gel confined in a narrow channel, and…
We study condensation in one-dimensional transport models with a kinetic constraint. The kinetic constraint results in clustering of immobile vehicles; these clusters can grow to macroscopic condensates, indicating the onset of dynamic…
We have recorded the swarming-like collective migration of a large number of keratocytes (tissue cells obtained from the scales of goldfish) using long-term videomicroscopy. By increasing the overall density of the migrating cells, we have…
In this paper we propose and study a hybrid discrete in continuous mathematical model of collective motion under alignment and chemotaxis effect. Starting from the paper by Di Costanzo et al (2015a), in which the Cucker-Smale model (Cucker…
The Keller-Segel model is a well-known system representing chemotaxis in living organisms. We study the convergence of a generalized nonlinear variant of the Keller-Segel to the degenerate Cahn-Hilliard system. This analysis is made…
We show that the Keller-Segel model in one dimension with Neumann boundary conditions and quadratic cellular diffusion has an intricate phase transition diagram depending on the chemosensitivity strength. Explicit computations allow us to…
Cellular traffic prediction is of great importance for operators to manage network resources and make decisions. Traffic is highly dynamic and influenced by many exogenous factors, which would lead to the degradation of traffic prediction…
There is increasing interest in the analysis of biological tissue, its organization and its dynamics with the help of mathematical models. In the ideal case emergent properties on the tissue scale can be derived from the cellular scale.…
In this work we describe a hyperbolic model with cell-cell repulsion with a dynamics in the population of cells. More precisely, we consider a population of cells producing a field (which we call "pressure") which induces a motion of the…
Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…
We investigate a cellular automaton (CA) model of traffic on a bi-directional two-lane road. Our model is an extension of the one-lane CA model of {Nagel and Schreckenberg 1992}, modified to account for interactions mediated by passing, and…
As a class of nonlinear partial differential equations, the Keller-Segel system is widely used to model chemotaxis in biology. In this paper, we present the construction and analysis of a decoupled linear, mass-conservative, block-centered…
Moving-habitat models track the density of a population whose suitable habitat shifts as a consequence of climate change. Whereas most previous studies in this area consider 1-dimensional space, we derive and study a spatially 2-dimensional…