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The effect of mechanical interactions between cells in the spreading of bacterial populations was investigated in one-dimensional space. A continuum-mechanics approach, comprising cell migration, proliferation, and exclusion processes, was…

生物物理 · 物理学 2015-12-15 Waipot Ngamsaad , Suthep Suantai

We study self-propelled particles with velocity reversal interacting by uniaxial (nematic) alignment within a coarse-grained hydrodynamic theory. Combining analytical and numerical continuation techniques, we show that the physics of this…

统计力学 · 物理学 2016-11-30 Robert Großmann , Fernando Peruani , Markus Bär

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

生物物理 · 物理学 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

Many mathematical models for biological phenomena, such as the spread of diseases, are based on reaction-diffusion equations for densities of interacting cell populations. We present a consistent derivation of reaction-diffusion equations…

偏微分方程分析 · 数学 2026-02-23 Marzia Bisi , Davide Cusseddu , Ana Jacinta Soares , Romina Travaglini

The transport equation of active motion is generalised to consider time-fractional dynamics for describing the anomalous diffusion of self-propelled particles observed in many different systems. In the present study, we consider an…

统计力学 · 物理学 2023-10-27 Francisco J. Sevilla , Guillermo Chacón-Acosta , Trifce Sandev

Motivated by the study of reversal behaviour of myxobacteria, in this article we are interested in a kinetic model for reversal dynamics, in which particles with directions close to be opposite undergo binary collision resulting in…

偏微分方程分析 · 数学 2023-05-22 Amic Frouvelle , Laura Kanzler , Christian Schmeiser

Starting from a particle model describing self-propelled particles interacting through nematic alignment, we derive a macroscopic model for the particle density and mean direction of motion. We first propose a mean-field kinetic model of…

数学物理 · 物理学 2019-10-08 Pierre Degond , Sara Merino-Aceituno

Stochasticity is a defining feature of the pairwise forces governing interactions in biological systems-from molecular motors to cell-cell adhesion-yet its consequences on large-scale dynamics remain poorly understood. Here, we show that…

软凝聚态物质 · 物理学 2025-08-27 Henry Alston , Raphael Voituriez , Thibault Bertrand

The diffusion properties of self-propelled particles which move at constant speed and, in addition, reverse their direction of motion repeatedly are investigated. The internal dynamics of particles triggering these reversal processes is…

生物物理 · 物理学 2016-05-30 Robert Großmann , Fernando Peruani , Markus Bär

We introduce and discuss a kinetic framework describing the time evolution of the statistical distributions of a population divided into the compartments of susceptible, infectious, recovered, and resistant in the presence of a microbial…

种群与进化 · 定量生物学 2026-05-07 Marco Menale , Giuseppe Toscani , Mattia Zanella

In this work we propose a model to describe the statistical fluctuations of the self-driven objects (species A) walking against an opposite crowd (species B) in order to simulate the regime characterized by stop-and-go waves in the context…

统计力学 · 物理学 2014-08-12 Roberto da Silva , Agenor Hentz , Alexandre Alves

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

细胞行为 · 定量生物学 2018-08-02 Christèle Etchegaray , Nicolas Meunier

This paper studies a stochastic model that describes the evolution of vehicle densities in a road network. It is consistent with the class of (deterministic) kinematic wave models, which describe traffic flows on the basis of conservation…

概率论 · 数学 2021-02-11 Michel Mandjes , Jaap Storm

Stochastic models of diffusion with excluded-volume effects are used to model many biological and physical systems at a discrete level. The average properties of the population may be described by a continuum model based on partial…

化学物理 · 物理学 2012-12-20 Maria Bruna , S. Jonathan Chapman

In this paper, we consider 1D agent-based and kinetic models of aggregation with reversals. In particular, we fit a Gamma distribution to represent the run times in myxobacteria and analyze numerically the importance of non-exponential…

生物物理 · 物理学 2024-11-05 Michael Batista , Patrick Murphy , Oleg A. Igoshin , Misha Perepelitsa , Ilya Timofeyev

Bacterial swarming is a rapid mass-migration, in which thousands of cells spread collectively to colonize a surface. Physically, swarming is a natural example of active particles that use energy to generate motion. Accordingly,…

We study the urban-scale macroscopic traffic flow in city networks. Star graph is considered as traffic network. Star graphs with controlled traffic flow are transformed to various cell-transmission graphs by using the cell transmission…

适应与自组织系统 · 物理学 2019-12-10 Takashi Nagatani

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

种群与进化 · 定量生物学 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

Cell-cell adhesion plays a vital role in the development and maintenance of multicellular organisms. One of its functions is regulation of cell migration, such as occurs, e.g. during embryogenesis or in cancer. In this work, we develop a…

组织与器官 · 定量生物学 2024-03-08 Anna Zhigun , Mabel Lizzy Rajendran

The activity of biological cells is primarily based on chemical reactions and typically modeled as a reaction-diffusion system. Cells are, however, highly crowded with macromolecules, including a variety of molecular machines such as…

生物物理 · 物理学 2018-11-02 Yuichi Togashi
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