相关论文: Non-extensive radiobiology

We present a theoretical agent-based model of cell evolution under the action of cytotoxic treatments, such as radioteraphy or chemoteraphy. The major features of cell cycle and proliferation, cell damage and repair, and chemical diffusion…

There is a conception that Boltzmann-Gibbs statistics cannot yield the long tail distribution. This is the justification for the intensive research of nonextensive entropies (i.e. Tsallis entropy and others). Here the error that caused this…

From a systems biology perspective the majority of cancer models, although interesting and providing a qualitative explanation of some problems, have a major disadvantage in that they usually miss a genuine connection with experimental…

During the past dozen years there have been numerous articles on a relation between entropy and probability which is non-additive and has a parameter $q$ that depends on the nature of the thermodynamic system under consideration. For $q=1$…

By using the maximum entropy principle, with Tsallis entropy, we obtain an explicit dependence for energy distribution of earthquakes. This function describes very well the observations in a wide range of energies, where other distribution…

We demonstrate and characterize a first-principles approach to modeling the mass action dynamics of metabolism. Starting from a basic definition of entropy expressed as a multinomial probability density using Boltzmann probabilities with…

We consider the problem of guessing the realization of a random variable but under more general Tsallis' non-extensive entropic framework rather than the classical Maxwell-Boltzman-Gibbs-Shannon framework. We consider both the conditional…

An important research topic in survival analysis is related to the modeling and estimation of the cure rate, i.e. the proportion of subjects that will never experience the event of interest. However, most estimation methods proposed so far…

We introduce what we call the second-order Boltzmann-Gibbs principle, which allows to replace local functionals of a conservative, one-dimensional stochastic process by a possibly nonlinear function of the conserved quantity. This…

We revisit the cut-off prescriptions which are needed in order to specify completely the form of Tsallis' maximum entropy distributions. For values of the Tsallis entropic parameter $q>1$ we advance an alternative cut-off prescription and…

The paper presents a computational stochastic model of virtual cells irradiation, based on Quasi-Markov Chain Monte Carlo method and using biophysical input. The model is based on a stochastic tree of probabilities for each cell of the…

Starting from a general equation for organism (or cell system) growth and attributing additional cell death rate (besides the natural rate) to therapy, we derive an equation for cell response to {\alpha} radiation. Different from previous…

Previous results on Renyi and Wang's formalism of the Tsallis thermostatics are founded by using an extensive variable z connected to the entropic parameter q. It is shown that in the thermodynamical limit both the Tsallis and Renyi…

In this paper we give an interpretation of Tsallis' nonextensive statistical mechanics based upon the information-theoretic point of view of Luzzi et al. [cond-mat/0306217; cond-mat/0306247; cond-mat/0307325], suggesting Tsallis' entropy to…

In this paper we recall for physicists how it is possible, using the principle of maximization of the Boltzmann-Shannon entropy, to derive the Burr-Bingh-Maddala (burr12) double power law probability distribution function and its…

The aim of the present paper is to present a careful and accessible discussion of the formal aspects of Boltzmann-Gibbs and Tsallis entropies. We begin with a brief overview of Boltzmann-Gibbs entropy, highlighting its main properties and…

The properties of the nonextensive parameter q and the Tsallis distribution for self-gravitating systems are studied. A mathematical expression of q is deduced based on the generalized Boltzmann equation, the q-H theorem and the generalized…

We propose a general approach, named by us hyperstatistics, to treat complex systems, in which Boltzmann-Gibbs statistics breaks down in domains of the system. Hyperstatistics preserves the concavity of nonadditive $q$-entropy. We obtain…

In this work, we investigate the population dynamics of tumor cells under therapeutic pressure. Although drug treatment initially induces a reduction in tumor burden, treatment failure frequently occurs over time due to the emergence of…

The original canonical ensemble formalism for the nonextensive entropy thermostatistics is reconsidered. It is shown that the unambiguous connection of the statistical mechanics with the equilibrium thermodynamics is provided if the…