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We present a general computational theory of stem cell networks and their developmental dynamics. Stem cell networks are special cases of developmental control networks. Our theory generates a natural classification of all possible stem…

其他定量生物学 · 定量生物学 2016-07-18 Eric Werner

We report a detailed study of neuromorphic switching behaviour in inherently complex percolating networks of self-assembled metal nanoparticles. We show that variation of the strength and duration of the electric field applied to this…

无序系统与神经网络 · 物理学 2019-03-06 S. K. Bose , S. Shirai , J. B. Mallinson , S. A. Brown

The study of dynamical systems defined on complex networks provides a natural framework with which to investigate myriad features of neural dynamics, and has been widely undertaken. Typically, however, networks employed in theoretical…

神经元与认知 · 定量生物学 2013-02-22 Reuben O'Dea , Jonathan J. Crofts , Marcus Kaiser

Mathematical models of stem cell differentiation are commonly based upon the concept of subsequent cell fate decisions, each controlled by a gene regulatory network. These networks exhibit a multistable behavior and cause the system to…

定量方法 · 定量生物学 2011-07-06 Christian Breindl , Daniella Schittler , Steffen Waldherr , Frank Allgöwer

Spike-timing-dependent plasticity (STDP) has recently been shown in some physiological studies. STDP depends on the precise temporal relationship of pre- and post-synaptic spikes. Many authors have indicated that a precise balance between…

无序系统与神经网络 · 物理学 2009-11-07 Narihisa Matsumoto , Masato Okada

Spiking neural networks (SNN) are a biologically inspired model of neural networks with certain brain-like properties. In the past few decades, this model has received increasing attention in computer science community, owing also to the…

神经与进化计算 · 计算机科学 2024-03-28 Prithwineel Paul , Petr Sosik , Lucie Ciencialova

We formulate general rules for a coarse-graining of the dynamics, which we term `symbolic dynamics', of feedback networks with monotone interactions, such as most biological modules. Networks which are more complex than simple cyclic…

定量方法 · 定量生物学 2009-03-04 Simone Pigolotti , Sandeep Krishna , Mogens H. Jensen

Critical brain hypothesis has been intensively studied both in experimental and theoretical neuroscience over the past two decades. However, some important questions still remain: (i) What is the critical point the brain operates at? (ii)…

神经元与认知 · 定量生物学 2019-12-19 Mahsa Khoshkhou , Afshin Montakhab

We study the collective dynamics of a Leaky Integrate and Fire network in which precise relative phase relationship of spikes among neurons are stored, as attractors of the dynamics, and selectively replayed at differentctime scales. Using…

神经元与认知 · 定量生物学 2012-10-26 Silvia Scarpetta , Ferdinando Giacco

We consider neural networks from the point of view of dynamical systems theory. In this spirit we review recent results dealing with the following questions, adressed in the context of specific models. 1. Characterizing the collective…

适应与自组织系统 · 物理学 2010-11-09 B. Cessac

We demonstrate a spiking neural network for navigation motivated by the chemotaxis network of Caenorhabditis elegans. Our network uses information regarding temporal gradients in the tracking variable's concentration to make navigational…

神经与进化计算 · 计算机科学 2014-10-30 Shibani Santurkar , Bipin Rajendran

Understanding cognitive flexibility and task-switching mechanisms in neural systems requires biologically plausible computational models. This tutorial presents a step-by-step approach to constructing a spiking neural network (SNN) that…

神经元与认知 · 定量生物学 2025-03-07 Ashwin Viswanathan Kannan , Madhumitha Ganesan

We study in this paper the effect of an unique initial stimulation on random recurrent networks of leaky integrate and fire neurons. Indeed given a stochastic connectivity this so-called spontaneous mode exhibits various non trivial…

神经与进化计算 · 计算机科学 2007-05-23 H. Soula , G. Beslon , O. Mazet

The plasticity of the conduction delay between neurons plays a fundamental role in learning. However, the exact underlying mechanisms in the brain for this modulation is still an open problem. Understanding the precise adjustment of…

神经与进化计算 · 计算机科学 2020-11-19 Alireza Nadafian , Mohammad Ganjtabesh

Triplet-based Spike Timing Dependent Plasticity (TSTDP) is a powerful synaptic plasticity rule that acts beyond conventional pair-based STDP (PSTDP). Here, the TSTDP is capable of reproducing the outcomes from a variety of biological…

神经与进化计算 · 计算机科学 2013-04-02 Mostafa Rahimi Azghadi , Said Al-Sarawi , Derek Abbott , Nicolangelo Iannella

Spiking neural networks are motivated from principles of neural systems and may possess unexplored advantages in the context of machine learning. A class of \textit{convolutional spiking neural networks} is introduced, trained to detect…

神经与进化计算 · 计算机科学 2018-08-27 Daniel J. Saunders , Hava T. Siegelmann , Robert Kozma , Miklós Ruszinkó

Spiking Neural Networks (SNNs) are promising brain-inspired models known for low power consumption and superior potential for temporal processing, but identifying suitable learning mechanisms remains a challenge. Despite the presence of…

神经与进化计算 · 计算机科学 2025-08-20 Yuzhe Liu , Xin Deng , Qiang Yu

Spiking Neural Networks (SNNs) are brain-inspired, event-driven machine learning algorithms that have been widely recognized in producing ultra-high-energy-efficient hardware. Among existing SNNs, unsupervised SNNs based on synaptic…

神经与进化计算 · 计算机科学 2022-09-20 Mingyuan Meng , Xingyu Yang , Lei Bi , Jinman Kim , Shanlin Xiao , Zhiyi Yu

Self-organizing memristive networks are physical circuits that dynamically reconfigure their circuitry in response to external input signals. Their adaptive behavior arises from intrinsic neuro-synaptic dynamics combined with a…

无序系统与神经网络 · 物理学 2026-04-28 Yinhao Xu , Georg A. Gottwald , Zdenka Kuncic

In vitro and in vivo spiking activity clearly differ. Whereas networks in vitro develop strong bursts separated by periods of very little spiking activity, in vivo cortical networks show continuous activity. This is puzzling considering…

神经元与认知 · 定量生物学 2018-07-24 Johannes Zierenberg , Jens Wilting , Viola Priesemann