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Because of the double-helical structure of DNA, in which two strands of complementary nucleotides intertwine around each other, a covalently closed DNA molecule with no interruptions in either strand can be viewed as two interlocked…

生物大分子 · 定量生物学 2015-05-13 Lauren A. Britton , Wilma K. Olson , Irwin Tobias

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

软凝聚态物质 · 物理学 2009-10-30 Philip Nelson

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

软凝聚态物质 · 物理学 2008-02-03 C. S. O'Hern , Randall D. Kamien , T. C. Lubensky , Philip Nelson

Nucleic acids are highly deformable helical molecules constantly stretched, twisted and bent in their biological functioning. Single molecule experiments have shown that double stranded (ds)-RNA and standard ds-DNA have opposite…

软凝聚态物质 · 物理学 2023-06-28 Marco Zoli

Helical molecules change their twist number under the effect of a mechanical load. We study the twist-stretch relation for a set of short DNA molecules modeled by a mesoscopic Hamiltonian. Finite temperature path integral techniques are…

软凝聚态物质 · 物理学 2017-09-19 Marco Zoli

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this…

软凝聚态物质 · 物理学 2009-10-28 Randall D. Kamien , Tom C. Lubensky , Philip Nelson , Corey S. O'Hern

The model of the deformation of DNA macromolecule is developed with the accounting of two types of components of deformation: external and internal. External components describe the bend, twist and stretch of the double helix. The internal…

软凝聚态物质 · 物理学 2020-12-01 P. P. Kanevska , S. N. Volkov

The question of the value of the pitch angle of DNA is visited from the perspective of a geometrical analysis of transcription. It is suggested that for transcription to be possible, the pitch angle of B-DNA must be smaller than the angle…

生物物理 · 物理学 2015-06-05 Kasper W. Olsen , Jakob Bohr

The twisting deformation of mechanically stretched DNA molecules is studied by a coarse grained Hamiltonian model incorporating the fundamental interactions that stabilize the double helix and accounting for the radial and angular base pair…

软凝聚态物质 · 物理学 2017-12-15 Marco Zoli

It is suggested that there is an interesting transition in double helices. The transition is between a helix, which has maximal torsion for the constituting helical strands, and a double helix which is nearly optimally packed illustrated by…

生物物理 · 物理学 2018-09-18 Kasper W. Olsen , Jakob Bohr

Spider dragline silk supercontracts as humidity increases, displaying large axial shortening together with a reproducible macroscopic twist. The physical origin of this torsion remains debated and is often attributed to helically arranged…

生物物理 · 物理学 2026-01-21 V. Fazio , G. Puglisi , G. Saccomandi

A double stranded DNA molecule under the stress of a pulling force acting on the strand terminals exhibits a partially denatured structure or can be completely unzipped depending the magnitude of the pulling force. A scaling argument for…

统计力学 · 物理学 2009-09-25 Jeff Z. Y. Chen

The spontaneous formation of double helices for filaments under torsion is common and significant. For example, the research on the supercoiling of DNA is helpful for understanding the replication and transcription of DNA. Similar double…

软凝聚态物质 · 物理学 2016-12-09 Hongyuan Li , Shumin Zhao , Minggang Xia , Siyu He , Qifan Yang , Yuming Yan , Hanqiao Zhao

The interplay between global constraints and local material properties of chain molecules is a subject of emerging interest. Studies of molecules that are intrinsically chiral, such as double-stranded DNA, is one example. Their properties…

生物物理 · 物理学 2013-11-27 Jakob Bohr , Kasper W. Olsen

Twisting is a novel technique for creating strongly correlated effects in two-dimensional bilayered materials, and can tunably generate nontrivial topological properties, magnetism, and superconductivity. Magnetism is particularly…

强关联电子 · 物理学 2023-07-20 Zhigang Song , Jingshan Qi , Olivia Liebman , Prineha Narang

Multistep denaturation in a short circular DNA molecule is analyzed by a mesoscopic Hamiltonian model which accounts for the helicoidal geometry. Computation of melting profiles by the path integral method suggests that stacking…

软凝聚态物质 · 物理学 2012-04-13 Marco Zoli

The simplest model of DNA mechanics describes the double helix as a continuous rod with twist and bend elasticity. Recent work has discussed the relevance of a little-studied coupling $G$ between twisting and bending, known to arise from…

统计力学 · 物理学 2019-04-08 Stefanos K. Nomidis , Enrico Skoruppa , Enrico Carlon , John F. Marko

DNA stretching experiments are usually interpreted using the worm-like chain model; the persistence length A appearing in the model is then interpreted as the elastic stiffness of the double helix. In fact the persistence length obtained by…

软凝聚态物质 · 物理学 2009-10-30 Philip Nelson

The folding angle distribution of stretched and negatively supercoiled DNA double-helix is investigated based on a theoretical model we proposed earlier [H. Zhou et al., Phys. Rev. Lett. 82, 4560 (1999)]. It is shown that pulling can…

软凝聚态物质 · 物理学 2007-05-23 Zhou Haijun , Ou-Yang Zhong-can

The experiment that the high spin selectivity and the length-dependent spin polarization are observed in double-stranded DNA [Science ${\bf 331}$, 894 (2011)], is elucidated by considering the combination of the spin-orbit coupling, the…

介观与纳米尺度物理 · 物理学 2015-06-03 Ai-Min Guo , Qing-feng Sun
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