相关论文: Role of anisotropy for protein-protein encounter
We investigate a diffusive motion of a system of interacting Brownian particles in quasi-one-dimensional micropores. In particular, we consider a semi-infinite 1D geometry with a partially absorbing boundary and the hard-core inter-particle…
Small angle neutron scattering intensity distributions taken from cytochrome C and lysozyme protein solutions show a rising intensity at very small wave vector, Q, which can be interpreted in terms of the presence of a weak long-range…
Anisotropic colloidal particles exhibit complex dynamics which play a crucial role in their functionality, transport and phase behaviour. In this work, we investigate the two-dimensional diffusion of smoothly curved colloidal rods -- also…
By means of contact dynamics simulations, we investigate a dense packing composed of polyhedral particles under quasistatic shearing. The effect of particle shape is analyzed by comparing the polyhedra packing with a packing of similar…
It is intuitive that the diffusivity of an isolated particle differs from those in a monodisperse suspension, in which hydrodynamic interactions between the particles are operative. Batchelor (1976,1983) calculated how hydrodynamic…
Physical experiments can characterize the elastic response of granular materials in terms of macroscopic state-variables, namely volume (packing) fraction and stress, while the microstructure is not accessible and thus neglected. Here, by…
Anisotropic flow is accredited to have effects from the initial state geometry and fluctuations in the nuclear overlap region. The elliptic flow ($v_2$) and triangular flow ($v_3$) coefficients of the final state particles are expected to…
Using event-driven kinetic Monte-Carlo simulations we investigate the early stage of non-equilibrium surface growth in a generic model with anisotropic interactions among the adsorbed particles. Specifically, we consider a two-dimensional…
The effect of interactions on dynamics of coupled motor proteins is investigated theoretically. A simple stochastic discrete model, that allows to calculate explicitly the dynamic properties of the system, is developed. It is shown that…
Besides the chemical constituents, it is the lattice geometry that controls the most important material properties. In many interesting compounds, the arrangement of elements leads to pronounced anisotropies, which reflect into a varying…
The predictions of event anisotropy parameters from transport model RQMD are compared with the recent experimental measurements for 158$A$ GeV Pb+Pb collisions. Using the same model, we study the time evolution of event anisotropy at 2$A$…
The strength of granular materials is highly dependent on grain connectivity (fabric), force transmission, and frictional mobilization at the particle scale. Furthermore, these bulk properties are strongly dependent on the geometry and…
Intracellular processes often rely on the timely encounter of mobile reaction partners, including intermittently motor-driven organelles. The underlying cytoskeletal network presents a complex landscape that both directs particle movement…
The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…
Protein folding processes are generally described statistically with the help of multidimensional free energy landscape, typically reduced to a 1-D free energy profile along good reaction co-ordinate. There are many physical parameters…
We review the theoretical analyses and simulations of the interactions between curvature-inducing proteins and biomembranes. Laterally isotropic proteins induce spherical budding, whereas anisotropic proteins, such as Bin/Amphiphysin/Rvs…
The mechanisms by which a protein's 3D structure can be determined based on its amino acid sequence have long been one of the key mysteries of biophysics. Often simplistic models, such as those derived from geometric constraints, capture…
Large deformations of soft materials are customarily associated with strong constitutive and geometrical nonlinearities that originate new modes of fracture. Some isotropic materials can develop strong fracture anisotropy, which manifests…
Despite the recognized importance of the multi-scale spatio-temporal organization of proteins, most computational tools can only access a limited spectrum of time and spatial scales, thereby ignoring the effects on protein behavior of the…
The structure of DNA Binding Proteins enables a strong interaction with their specific target site on DNA. However, recent single molecule experiment reported that proteins can diffuse on DNA. This suggests that the interactions between…