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In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

医学物理 · 物理学 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

Online adaptive radiation therapy (ART) has great promise to significantly reduce normal tissue toxicity and/or improve tumor control through real-time treatment adaptations based on the current patient anatomy. However, the major technical…

医学物理 · 物理学 2015-05-18 Chunhua Men , Xun Jia , Steve. B. Jiang

Computed tomography (CT) to cone-beam computed tomography (CBCT) deformable image registration (DIR) is a crucial step in adaptive radiation therapy. Current intensity-based registration algorithms, such as demons, may fail in the context…

医学物理 · 物理学 2017-08-23 Xin Zhen , Xuejun Gu , Hao Yan , Linghong Zhou , Xun Jia , Steve B. Jiang

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

We present a highly parallel method for accurate and efficient variational deformable 3D image registration on a consumer-grade graphics processing unit (GPU). We build on recent matrix-free variational approaches and specialize the…

计算机视觉与模式识别 · 计算机科学 2018-12-18 Daniel Budelmann , Lars König , Nils Papenberg , Jan Lellmann

Deformable Image Registration (DIR) of MR and CT images is one of the most challenging registration task, due to the inherent structural differences of the modalities and the missing dense ground truth. Recently cycle Generative Adversarial…

计算机视觉与模式识别 · 计算机科学 2018-07-20 Christine Tanner , Firat Ozdemir , Romy Profanter , Valeriy Vishnevsky , Ender Konukoglu , Orcun Goksel

Deformable Image Registration (DIR) is essential for aligning medical images that exhibit anatomical variations, facilitating applications such as disease tracking and radiotherapy planning. While classical iterative methods and deep…

计算机视觉与模式识别 · 计算机科学 2025-09-08 Jihe Li , Xiang Liu , Fabian Zhang , Xia Li , Xixin Cao , Ye Zhang , Joachim Buhmann

Objective: Clinical implementation of deformable image registration (DIR) requires voxel-based spatial accuracy metrics such as manually identified landmarks, which are challenging to implement for highly mobile gastrointestinal (GI)…

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

医学物理 · 物理学 2025-07-22 Xia Li , Runzhao Yang , Muheng Li , Xiangtai Li , Antony J. Lomax , Joachim M. Buhmann , Ye Zhang

We present a novel computational approach to fast and memory-efficient deformable image registration. In the variational registration model, the computation of the objective function derivatives is the computationally most expensive…

计算机视觉与模式识别 · 计算机科学 2018-04-30 Lars König , Jan Rühaak , Alexander Derksen , Jan Lellmann

Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25…

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

医学物理 · 物理学 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

Adaptive radiotherapy (ART), especially online ART, effectively accounts for positioning errors and anatomical changes. One key component of online ART is accurately and efficiently delineating organs at risk (OARs) and targets on online…

Intra-fraction motion in radiotherapy is commonly modeled using deformable image registration (DIR). However, existing methods often struggle to balance speed and accuracy, limiting their applicability in clinical scenarios. This study…

医学物理 · 物理学 2024-02-09 Xia Li , Fabian Zhang , Muheng Li , Damien Weber , Antony Lomax , Joachim Buhmann , Ye Zhang

The widespread adoption of on-board volumetric imaging in cancer radiotherapy has stimulated research efforts to develop online adaptive radiotherapy techniques to handle the inter-fraction variation of the patient's geometry. Such efforts…

医学物理 · 物理学 2015-05-14 Chunhua Men , Xuejun Gu , Dongju Choi , Amitava Majumdar , Ziyi Zheng , Klaus Mueller , Steve B. Jiang

Objective: Deformable image registration is a fundamental problem in medical image analysis, with applications such as longitudinal studies, population modeling, and atlas based image segmentation. Registration is often phrased as an…

计算机视觉与模式识别 · 计算机科学 2018-10-22 Simon Ekström , Filip Malmberg , Håkan Ahlström , Joel Kullberg , Robin Strand

Deformable Image Registration (DIR) plays a significant role in quantifying deformation in medical data. Recent Deep Learning methods have shown promising accuracy and speedup for registering a pair of medical images. However, in 4D (3D +…

图像与视频处理 · 电气工程与系统科学 2023-05-26 Xiao Liang , Shan Lin , Fei Liu , Dimitri Schreiber , Michael Yip

The accuracy of deformable image registration (DIR) has a significant dosimetric impact in radiation treatment planning. We evaluated accuracy of various DIR algorithms using variations of the deformation point and volume. The reference…

When choosing a deformable image registration (DIR) approach for images with large deformations and content mismatch, the realism of found transformations often needs to be traded off against the required runtime. DIR approaches using deep…

计算机视觉与模式识别 · 计算机科学 2025-01-29 Georgios Andreadis , Eduard Ruiz Munné , Thomas H. W. Bäck , Peter A. N. Bosman , Tanja Alderliesten

Deformable image registration (DIR) is an enabling technology in many diagnostic and therapeutic tasks. Despite this, DIR algorithms have limited clinical use, largely due to a lack of benchmark datasets for quality assurance during…

计算机视觉与模式识别 · 计算机科学 2025-01-17 Edward R Criscuolo , Yao Hao , Zhendong Zhang , Trevor McKeown , Deshan Yang
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