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Coarse-grained model for saturated (DCPC, DLPC, DMPC, DPPC, DSPC) and unsaturated (POPC, DOPC) phospholipids is introduced within the Single Chain Mean Field theory. A single set of parameters adjusted for DMPC bilayers gives an adequate…

软凝聚态物质 · 物理学 2014-05-19 Yachong Guo , Sergey Pogodin , Vladimir A. Baulin

Recent developments in lipid membrane models for simulations are reviewed. To reduce computational costs, various coarse-grained molecular models have been proposed. Among them, implicit solvent (solvent-free) molecular models are…

软凝聚态物质 · 物理学 2015-05-13 Hiroshi Noguchi

We present a phenomenological theory for the phase behavior of ternary mixtures of cholesterol and saturated and unsaturated lipids, one which describes both liquid and gel phases, and illuminates the mechanism of the behavior. In a binary…

生物物理 · 物理学 2008-06-05 Gregory Garbès Putzel , Michael Schick

In vivo and in vitro lipid bilayers are commonly supported by subcellular structures, particles, and artificial substrates. Deformation of the underlying structure can lead to large, localized deformations as the bilayer deforms to avoid…

软凝聚态物质 · 物理学 2014-03-17 Austin Fergusson , Ravi Kappiyoor , Ganesh Balasubramanian , Ishwar K. Puri , Douglas P. Holmes

Biomembranes, primarily composed of lipid bilayers, are not merely passive barriers but dynamic and complex materials whose shapes are governed by the principles of soft matter physics. This review explores the shape problem in biomembranes…

计算物理 · 物理学 2026-05-05 Zhong-Can Ou-Yang , Tao Xu

Polymer microgels exhibit intriguing macroscopic flow properties arising from their unique microscopic structure. Microgel colloids usually comprise a crosslinked polymer network with a radially decaying density profile, resulting in a…

软凝聚态物质 · 物理学 2025-02-10 Maxime Bergman , Yixuan Xu , José Muñéton Díaz , Zhang Chi , Thomas G. Mason , Frank Scheffold

We use a coarse-grained molecular dynamics simulation to investigate the interaction between neutral or charged nanoparticles (NPs) and a vesicle consisting of neutral and negatively charged lipids. We focus on the interaction strengths of…

软凝聚态物质 · 物理学 2019-07-25 Naofumi Shimokawa , Hiroaki Ito , Yuji Higuchi

Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting.…

Lipid membranes in a physiological context cannot be understood without taking into account their mobile environment. Here, we report on a high energy-resolution neutron backscattering study to investigate slow motions on nanosecond time…

生物物理 · 物理学 2007-05-23 Maikel C. Rheinstädter , Tilo Seydel , Tim Salditt

Critical lateral pressure for a pore formation and phase diagram of porous membrane are derived analytically as functions of the microscopic parameters of the lipid chains. The derivation exploits path-integral calculation of the free…

软凝聚态物质 · 物理学 2015-06-18 S. I. Mukhin , B. B. Kheyfets

Surface tension-driven flow techniques have recently emerged as an efficient means of shedding light into the rheology of thin polymer films. Motivated by experimental and theoretical approaches in films bearing a varying surface…

软凝聚态物质 · 物理学 2017-04-26 Ioannis Tanis , Hendrik Meyer , Thomas Salez , Elie Raphaël , Anthony C. Maggs , Jörg Baschnagel

Collagen fibrils are versatile self-assembled structures that provide mechanical integrity within mammalian tissues. The radius of collagen fibrils vary widely depending on experimental conditions \textit{in vitro} or anatomical location…

软凝聚态物质 · 物理学 2018-02-26 Samuel Cameron , Laurent Kreplak , Andrew D. Rutenberg

The tensile force along a cylindrical lipid bilayer tube is proportional to the membrane's bending modulus and inversely proportional to the tube radius. We show that this relation, which is experimentally exploited to measure bending…

软凝聚态物质 · 物理学 2007-05-23 Vagelis A. Harmandaris , Markus Deserno

In biological membranes, alpha-tocopherols ({\alpha}-toc; vitamin E) protect polyunsaturated lipids from free radicals. Although the interactions of {\alpha}-toc with non-oxidized lipid bilayers have been studied, their on oxidized bilayers…

生物物理 · 物理学 2017-04-05 Phansiri Boonnoy , Mikko Karttunen , Jirasak Wong-ekkabut

Diffusion in cell membranes is not just simple two-dimensional Brownian motion, but typically depends on the timescale of the observation. The physical origins of this anomalous sub-diffusion are unresolved, and model systems capable of…

生物物理 · 物理学 2017-10-25 H. L. E. Coker , M. R. Cheetham , D. R. Kattnig , Y. J. Wang , S. Garcia-Manyes , M. I. Wallace

Electrochemical devices such as solid oxide fuel cells (SOFC) may greatly benefit from the implementation of nanoengineered thin-film multifunctional layers providing, alongside enhanced electrochemical activity, improved mechanical, and…

Collagen fibrils are the building block of many biological tissues, which viability depend on the fibrils properties. Altered properties of collagen fibrils are central to the appearance of many diseases, while physiological or native…

软凝聚态物质 · 物理学 2026-05-08 Konstantinos Steiakakis , Alan Pichard , Maxime Vassaux

Free volume pockets or voids are important to many biological processes in cell membranes. Free volume fluctuations are a prerequisite for diffusion of lipids and other macromolecules in lipid bilayers. Permeation of small solutes across a…

软凝聚态物质 · 物理学 2009-11-10 Emma Falck , Michael Patra , Mikko Karttunen , Marja T. Hyvonen , Ilpo Vattulainen

The interaction potential between supported floating bilayers has been determined by grazing incidence specular and off-specular scattering using synchrotron radiation. Our measurements demonstrate that floating bilayers are significantly…

软凝聚态物质 · 物理学 2012-05-21 L. Malaquin , T. Charitat , J. Daillant , S. Lecuyer , G. Fragneto

Fibers of bent-core liquid crystals present an internal structure of a rolled smectic layer and can be used as optical waveguides. We used a field-theoretical Monte Carlo simulation to analyze the internal configuration of such fibers as a…

软凝聚态物质 · 物理学 2016-08-04 N. Atzin , O. Guzmán , J. J. de Pablo
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