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The brain produces rhythms in a variety of frequency bands. Some are likely by-products of neuronal processes; others are thought to be top-down. Produced entirely naturally, these rhythms have clearly recognizable beats, but they are very…

动力系统 · 数学 2020-06-09 Benjamin Ambrosio , Lai-Sang Young

In-vivo, cells are frequently exposed to multiple mechanical stimuli arising from the extracellular microenvironment, with deep impact on many biological functions. On the other hand, current methods for mechanobiology do not allow to…

细胞行为 · 定量生物学 2017-12-07 M. Monticelli , D. S. Jokhun , D. Petti , G. V. Shivashankar , R. Bertacco

Fifty years ago, Fitzugh introduced a phase portrait that became famous for a twofold reason: it captured in a physiological way the qualitative behavior of Hodgkin-Huxley model and it revealed the power of simple dynamical models to unfold…

动力系统 · 数学 2011-12-13 Alessio Franci , Guillaume Drion , Vincent Seutin , Rodolphe Sepulchre

The human brain is one of the most complex and intriguing scientific topics. The most established theory on neuronal communication is a pure electrical model based on the propagation of intracell cationic charges along the neurons. Here we…

神经元与认知 · 定量生物学 2024-03-26 Francisco Meseguer , Fernando Ramiro-Manzano

The FitzHugh-Nagumo (FHN) model serves as a fundamental neuronal model which is extensively studied across various dynamical scenarios, we explore the dynamics of a scalar FHN oscillator under the influence of white noise. Unlike previous…

无序系统与神经网络 · 物理学 2025-03-03 S. Hariharan , R. Suresh , V. K. Chandrasekar

The overdamped dynamics of a particle is in general affected by its interaction with the surrounding medium, especially out of equilibrium, and when the latter develops spatial and temporal correlations. Here we consider the case in which…

统计力学 · 物理学 2023-09-13 Davide Venturelli , Andrea Gambassi

Intensive computational and theoretical work has led to the development of mutliple mathematical models for bursting in respiratory neurons in the pre-B\"otzinger Complex (pre-B\"otC) of the mammalian brainstem. Nonetheless, these previous…

神经元与认知 · 定量生物学 2021-05-11 Muhammad U. Abdulla , Ryan S. Phillips , Jonathan E. Rubin

The distinct timescales of synaptic plasticity and neural activity dynamics play an important role in the brain's learning and memory systems. Activity-dependent plasticity reshapes neural circuit architecture, determining spontaneous and…

神经元与认知 · 定量生物学 2023-06-30 Heather L Cihak , Zachary P Kilpatrick

We analyse a one-dimensional model of hard particles, within ensembles of trajectories that are conditioned (or biased) to atypical values of the time-averaged dynamical activity. We analyse two phenomena that are associated with these…

统计力学 · 物理学 2015-11-18 Ian R. Thompson , Robert L. Jack

The effects of noise on the dynamics of nonlinear systems is known to lead to many counter-intuitive behaviors. Using simple planar limit cycle oscillators, we show that the addition of moderate noise leads to qualitatively different…

混沌动力学 · 物理学 2015-06-17 Jay M. Newby , Michael A. Schwemmer

We report on self-induced switchings between multiple distinct space--time patterns in the dynamics of a spatially extended excitable system. These switchings between low-amplitude oscillations, nonlinear waves, and extreme events strongly…

混沌动力学 · 物理学 2016-03-21 Gerrit Ansmann , Klaus Lehnertz , Ulrike Feudel

The dynamics of stochastic reaction networks within cells are inevitably modulated by factors considered extrinsic to the network such as for instance the fluctuations in ribsome copy numbers for a gene regulatory network. While several…

定量方法 · 定量生物学 2015-06-19 Christoph Zechner , Heinz Koeppl

We study analytically the dynamics and the micro-structural changes of a host medium caused by a driven tracer particle moving in a confined, quiescent molecular crowding environment. Imitating typical settings of active micro-rheology…

统计力学 · 物理学 2016-03-17 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

We investigate the simple one-dimensional driven model, the totally asymmetric exclusion process, coupled to mutually interactive Langmuir kinetics. This model is motivated by recent studies on clustering of motor proteins on microtubules.…

生物物理 · 物理学 2015-06-23 H. D. Vuijk , R. Rens , M. Vahabi , F. C. MacKintosh , A. Sharma

Recent experiments have demonstrated that it is possible to alter the dispersion of a medium without significantly altering its absorption or refractive index and that this may be done while a wave propagates through the medium. This…

光学 · 物理学 2010-06-10 Douglas H. Bradshaw , Michael D. Di Rosa

We investigate the influence of a self-propelling, out-of-equilibrium active particle on generalized elastic systems, including flexible and semiflexible polymers, fluid membranes, and fluctuating interfaces, while accounting for…

软凝聚态物质 · 物理学 2024-01-25 Alessandro Taloni

Cells use biochemical networks to translate environmental information into intracellular responses. These responses can be highly dynamic, but how the information is encoded in these dynamics remains poorly understood. Here we investigate…

细胞行为 · 定量生物学 2017-04-05 Garrett D. Potter , Tommy A. Byrd , Andrew Mugler , Bo Sun

The movement of single kinesin molecules was observed while applying noisy external forces that mimic intracellular active fluctuations. We found kinesin accelerates under noise, especially when a large hindering load is added. The behavior…

生物物理 · 物理学 2021-11-02 Takayuki Ariga , Keito Tateishi , Michio Tomishige , Daisuke Mizuno

The dynamics of units (molecules) with slowly relaxing internal states is studied as an iterated function system (IFS) for the situation common in e.g. biological systems where these units are subjected to frequent collisional interactions.…

软凝聚态物质 · 物理学 2009-11-11 Kunihiko Kaneko

Perturbations of fluid media can give rise to non-equilibrium dynamics, which may in turn cause motion of immersed inclusions. We consider perturbations ("activations") that are local in space and time, of a fluid density which is…

统计力学 · 物理学 2020-03-18 Christian M. Rohwer , Mehran Kardar , Matthias Krüger