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The thermodynamic (TD) properties of biological membranes play a central role for living systems. It has been suggested, for instance, that nonlinear pulses such as action potentials (APs) can only exist if the membrane state is in vicinity…

生物物理 · 物理学 2020-07-16 Christian Fillafer , Anne Paeger , Matthias F. Schneider

The phenomenon of coherent energetic pulse propagation in exciton-phonon molecular chains such as $\alpha$-helix protein is studied using an ODE system model of Davydov-Scott type, both with numerical studies using a new unconditionally…

生物物理 · 物理学 2015-06-12 Brenton LeMesurier

The emergence of electrical fields across biological membranes is central to our present understanding of biomembrane function. The most prominent example is the textbook model for the action potential that relies on transmembrane voltage…

生物物理 · 物理学 2020-08-10 Thomas Heimburg

Starting from the concept of binary interactions between pairs of particles, a kinetic framework for the description of the action potential dynamics on a neural network is proposed. It consists of two coupled levels: the description of a…

生物物理 · 物理学 2023-03-21 Martina Conte , Maria Groppi , Andrea Tosin

Eukaryotic cells possess motility mechanisms allowing them not only to self-propel but also to exert forces on obstacles (to push) and to carry cargoes (to pull). To study the inherent asymmetry between active pushing and pulling we model a…

生物物理 · 物理学 2015-06-15 Pierre Recho , Lev Truskinovsky

Signals recorded from neurons with extracellular planar sensors have a wide range of waveforms and amplitudes. This variety is a result of different physical conditions affecting the ion currents through a cellular membrane. The…

Our work stems from the consideration that the spreading of a disease is modulated by the individual's perception of the infected neighborhood and his/her strategy to avoid being infected as well. We introduced a general ``cellular agent''…

种群与进化 · 定量生物学 2008-01-20 Luca Sguanci , Pietro Lio' , Franco Bagnoli

Recent studies have revealed the complex structure of nerve signals in axons. Besides the electrical signal, mechanical and thermal effects are also detected in many experimental studies. In this paper, the mathematical models of heat…

生物物理 · 物理学 2021-05-04 Jüri Engelbrecht , Kert Tamm , Tanel Peets

The temporal and spatial development of Parkinson's disease has been characterised as the progressive formation of {\alpha}-synuclein aggregations through susceptible neuronal pathways. This article describes a new model for this…

神经元与认知 · 定量生物学 2017-02-20 Míriam R. García , Mathieu Cloutier , Peter Wellstead

We prove the existence of a phase transition for a stochastic model of interacting neurons. The spiking activity of each neuron is represented by a point process having rate $1 $ whenever its membrane potential is larger than a threshold…

概率论 · 数学 2018-08-15 P. A. Ferrari , A. Galves , I. Grigorescu , E. Löcherbach

Microplasmas operated at atmospheric pressure show a number of peculiar dynamic phenomena. One of these phenomena is self-pulsing, which is characterized by intrinsic pulsing behavior of a DC driven plasma discharge. This work focuses on…

等离子体物理 · 物理学 2012-08-21 Alexander Wollny , Markus Gebhardt , Torben Hemke , Ralf Peter Brinkmann , Thomas Mussenbrock

A number of factors, such as, cell-cell interactions and self-propulsion of cells driven by cytoskeletal forces determine tissue morphologies and dynamics. To explore the interplay between these factors in controlling the dynamics at the…

软凝聚态物质 · 物理学 2025-05-12 Rajsekhar Das , Xin Li , Sumit Sinha , D. Thirumalai

The structure of the axon-dendrite connections of neurons of the brain creates a rich spatial structure in which provided various combinations of signals surrounding neurons. Structure of dendritic trees and shape of dendritic spines allow…

人工智能 · 计算机科学 2014-07-25 Alexey Redozubov

A method is shown for preventing temporal broadening of ultrafast optical pulses in highly dispersive and fluctuating media for arbitrary signal-pulse profiles. Pulse pairs, consisting of a strong-field control-pulse and a weak-field…

光学 · 物理学 2021-11-17 Haider Zia

Active phenomena which involve force generation and motion play a key role in a number of phenomena in living cells such as cell motility, muscle contraction and the active transport of material and organelles. Here we discuss mechanical…

生物物理 · 物理学 2007-05-23 Frank Julicher

The inactivation of a Na+ channel occurs when the activation of the charged S4 segment of domain DIV is followed by the binding of an intracellular hydrophobic motif which blocks conduction through the ion pore. The voltage dependence of…

生物物理 · 物理学 2015-10-21 Samuel R Vaccaro

Propagation of pulses in myelinated fibers may be described by appropriate solutions of spatially discrete FitzHugh-Nagumo systems. In these systems, propagation failure may occur if either the coupling between nodes is not strong enough or…

软凝聚态物质 · 物理学 2009-03-08 A. Carpio , L. L. Bonilla

The work concerns the multiscale modeling of a nerve fascicle of myelinated axons. We present a rigorous derivation of a macroscopic bidomain model describing the behavior of the electric potential in the fascicle based on the…

偏微分方程分析 · 数学 2022-06-10 Carlos Jerez-Hanckes , Isabel A. Martínez Ávila , Irina Pettersson , Volodymyr Rybalko

We report an asymmetric behavior of optical pulses during their propagation through a time-varying linear optical medium. The refractive index of the medium is considered to be varying with time and complex such that a sufficient amount of…

光学 · 物理学 2020-07-17 Piyali Biswas , Harsh K. Gandhi , Vaibhab Mishra , Somnath Ghosh

Trans-membrane gradients and fluxes of cations (H+, Na+, K+, etc.) were deemed to be the rationale of electrical activities of aerobic cells/organelles, as per classical perceptions. Murburn concept (an umbrella of theorization based in…

神经元与认知 · 定量生物学 2026-04-29 Kelath Murali Manoj , Nagamani Sukumar
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