相关论文: Dosimetric equivalence of non-standard high dose r…

This study develops and validates a patient-specific Monte Carlo (MC) dosimetry framework for propagation-based phase-contrast breast CT (BCT) at the Imaging and Medical Beamline (IMBL), ANSTO Australian Synchrotron, for accurate mean…

Background and Objective: Accurate and reliable segmentation of the prostate gland in MR images can support the clinical assessment of prostate cancer, as well as the planning and monitoring of focal and loco-regional therapeutic…

In this paper we describe a new robotic brachytherapy needle-insertion system that is designed to replace the template used in the manual technique. After a brief review of existing robotic systems, we describe the requirements that we…

A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed. The GDS algorithm is intrinsically faster than…

High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual treatment planning expertise. The objective of this study is to develop a fully automated…

Brachytherapy involves bringing a radioactive source near tumor tissue using implanted needles. Image-guided brachytherapy planning requires amongst others, the reconstruction of the needles. Manually annotating these needles on patient…

We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…

Adaptive Radiotherapy (ART) is an emerging technique for treating cancer patients which facilitates higher delivery accuracy and has the potential to reduce toxicity. However, ART is also resource-intensive, requiring extra human and…

Brachytherapy for localized prostate cancer consists in destroying cancer by introducing iodine radioactive seeds into the gland through hollow needles. The planning of the position of the seeds and their introduction into the prostate is…

Purpose: Demonstrate quantitative characterization of 3D patient-specific absorbed dose distributions using Haralick texture analysis and interpret measures in terms of underlying physics and radiation dosimetry. Methods: Retrospective…

Purpose: Radiotherapy commonly relies on CT, but there is growing interest in using hybrid PET/MR. Therefore, dedicated hardware setups have been proposed for PET/MR systems which enable imaging in radiotherapy treatment position. These…

Conventional planning objectives in optimization of intensity-modulated radiotherapy treatment (IMRT) plans are designed to minimize the violation of dose-volume histogram (DVH) thresholds using penalty functions. Although successful in…

The purpose of this study was to use various dosimetrical indices to determine the best IMRT modality technique for treating patients with prostate cancer. Ten patients with prostate cancer were included in this study. Intensity modulated…

Accurate radiotherapy dose calculation depends on converting CT Hounsfield Units (HU) to relative electron density (RED) using calibration curves. This study compared three different CT-to-RED calibration curves-two derived from physical…

The high dose gradients near the source characteristics of brachytherapy are equivalent to nefarious effects if unnoticed errors take place during the patient treatment. In vivo dosimetry is the only method to quantify the delivered dose.…

Purpose: This study aims to optimize and characterize the response of a mPSD for in vivo dosimetry in HDR brachytherapy. Methods: An exhaustive analysis was carried out in order to obtain an optimized mPSD design that maximize the…

Introduction: Intra-organ radiation dose sensitivity is becoming increasingly relevant in clinical radiotherapy. One method for assessment involves partitioning delineated regions of interest and comparing the relative contributions or…

The physical and clinical benefits of charged particle therapy (CPT) are well recognised and recent developments have led to the rapid emergence of facilities, resulting in wider adoption worldwide. Nonetheless, the availability of CPT and…

Purpose: A novel rotating gamma stereotactic radiosurgery (SRS) system (Galaxy RTi) with real-time image guidance technology has been developed for high-precision SRS and frameless fractionated stereotactic radiotherapy (SRT). This work…

To compare the dosimetrical differences between plans generated by helical tomotherapy using 2D or 3D margining technique in in prostate cancer. Ten prostate cancer patients were included in this study. For 2D plans, planning target volume…