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We present a model of decentralized growth for Artificial Neural Networks (ANNs) inspired by the development and the physiology of real nervous systems. In this model, each individual artificial neuron is an autonomous unit whose behavior…

adap-org · 物理学 2007-05-23 Jens C. Astor , Christoph Adami

Can we objectively distinguish chemical systems that are able to process meaningful information from those that are not suitable for information processing? Here, we present a formal method to assess the semantic capacity of a chemical…

分子网络 · 定量生物学 2011-05-26 Dennis Görlich , Peter Dittrich

An object-oriented combinator chemistry was used to construct an artificial organism with a system architecture possessing characteristics necessary for organisms to evolve into more complex forms. This architecture supports modularity by…

神经与进化计算 · 计算机科学 2018-05-17 Lance R. Williams

In this paper, we propose Continuous Graph Flow, a generative continuous flow based method that aims to model complex distributions of graph-structured data. Once learned, the model can be applied to an arbitrary graph, defining a…

机器学习 · 计算机科学 2019-10-01 Zhiwei Deng , Megha Nawhal , Lili Meng , Greg Mori

We present an enhancement of exp(ASP), a system that generates explanation graphs for a literal l - an atom a or its default negation ~a - given an answer set A of a normal logic program P, which explain why l is true (or false) given A and…

人工智能 · 计算机科学 2021-09-20 Ly Ly Trieu , Tran Cao Son , Marcello Balduccini

Local interactions among biomolecules, and the role played by their environment, have gained increasing attention in modelling biochemical reactions. By defining the automaton of molecular perceptions, we explore an agent-based…

计算工程、金融与科学 · 计算机科学 2021-11-24 Stefano Maestri , Emanuela Merelli

Motivation: The design of enzymes is as challenging as it is consequential for making chemical synthesis in medical and industrial applications more efficient, cost-effective and environmentally friendly. While several aspects of this…

Self-sustaining autocatalytic networks play a central role in living systems, from metabolism at the origin of life, simple RNA networks, and the modern cell, to ecology and cognition. A collectively autocatalytic network that can be…

分子网络 · 定量生物学 2018-03-29 Mike Steel , Wim Hordijk

The automatic analysis of chemical literature has immense potential to accelerate the discovery of new materials and drugs. Much of the critical information in patent documents and scientific articles is contained in figures, depicting the…

计算机视觉与模式识别 · 计算机科学 2024-08-29 Lucas Morin , Martin Danelljan , Maria Isabel Agea , Ahmed Nassar , Valery Weber , Ingmar Meijer , Peter Staar , Fisher Yu

The ability of a chemical reaction network to generate itself by catalyzed reactions from constantly present environmental food sources is considered a fundamental property in origin-of-life research. Based on Kaufmann's autocatalytic sets,…

分子网络 · 定量生物学 2023-08-16 Dimitri Loutchko

Laboratory experiments play a key role in deciphering the chemistry of the interstellar medium (ISM) and the role that product complex organic molecules (COMs) may play in the origins of life. However, to date, most studies in experimental…

地球与行星天体物理 · 物理学 2022-01-26 Nigel J. Mason , Perry A. Hailey , Duncan V. Mifsud , James S. Urquhart

We present a systematic investigation using graph neural networks (GNNs) to model organic chemical reactions. To do so, we prepared a dataset collection of four ubiquitous reactions from the organic chemistry literature. We evaluate seven…

机器学习 · 计算机科学 2020-07-10 Serim Ryou , Michael R. Maser , Alexander Y. Cui , Travis J. DeLano , Yisong Yue , Sarah E. Reisman

Graphs are fundamental data structures which concisely capture the relational structure in many important real-world domains, such as knowledge graphs, physical and social interactions, language, and chemistry. Here we introduce a powerful…

机器学习 · 计算机科学 2018-03-12 Yujia Li , Oriol Vinyals , Chris Dyer , Razvan Pascanu , Peter Battaglia

We formally characterize a set of causality-based properties of metabolic networks. This set of properties aims at making precise several notions on the production of metabolites, which are familiar in the biologists' terminology. From a…

计算工程、金融与科学 · 计算机科学 2010-02-23 Chiara Bodei , Andrea Bracciali , Davide Chiarugi , Roberta Gori

Chemical systems are traditionally described by lists of species, reactions, and externally imposed kinetic laws, a framework that lacks an intrinsic algebraic structure governing how transformations compose. We propose an axiomatic…

This document is written with the intention to describe in detail a method and means by which a computer program can reason about the world and in so doing, increase its analogue to a living system. As the literature is rife and it is…

人工智能 · 计算机科学 2017-05-23 Christopher A. Tucker

Probabilistic inference provides a language for describing how organisms may learn from and adapt to their environment. The computations needed to implement probabilistic inference often require specific representations, akin to having the…

分子网络 · 定量生物学 2018-06-28 Yarden Katz , Michael Springer , Walter Fontana

The chemistry of an astrophysical environment is closely coupled to its dynamics, the latter often found to be complex. Hence, to properly model these environments a 3D context is necessary. However, solving chemical kinetics within a 3D…

计算物理 · 物理学 2024-05-07 S. Maes , F. De Ceuster , M. Van de Sande , L. Decin

Graph generation generally aims to create new graphs that closely align with a specific graph distribution. Existing works often implicitly capture this distribution through the optimization of generators, potentially overlooking the…

机器学习 · 计算机科学 2024-07-19 Song Wang , Zhen Tan , Xinyu Zhao , Tianlong Chen , Huan Liu , Jundong Li

Reaction systems are discrete dynamical systems inspired by bio-chemical processes, whose dynamical behaviour is expressed by set-theoretic operations on finite sets. Reaction systems thus provide a description of bio-chemical phenomena…

形式语言与自动机理论 · 计算机科学 2020-08-05 Alberto Dennunzio , Enrico Formenti , Luca Manzoni , Antonio E. Porreca