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Biopolymer gels such as fibrin and collagen networks are known to develop tensile axial stress when subject to torsion. This negative normal stress is opposite to the classical Poynting effect observed for most elastic solids including…

软凝聚态物质 · 物理学 2018-04-04 Mahsa Vahabi , Bart E. Vos , Henri C. G. de Cagny , Daniel Bonn , Gijsje H. Koenderink , F. C. MacKintosh

Hydrogels of semiflexible biopolymers such as collagen have been shown to contract axially under shear strain, in contrast to the axial dilation observed for most elastic materials. Recent work has shown that this behavior can be understood…

软凝聚态物质 · 物理学 2019-05-13 Jordan Shivers , Jingchen Feng , Abhinav Sharma , Fred C. MacKintosh

Motivated by recent experiments showing nonlinear elasticity of in vitro networks of the biopolymer actin cross-linked with filamin, we present an effective medium theory of flexibly cross-linked stiff polymer networks. We model such…

软凝聚态物质 · 物理学 2008-10-19 C. P. Broedersz , C. Storm , F. C. MacKintosh

The non-linear stress-strain relation for crosslinked polymer networks is studied using molecular dynamics simulations. Previously we demonstrated the importance of trapped entanglements in determining the elastic and relaxational…

软凝聚态物质 · 物理学 2009-10-31 Gary S. Grest , Mathias Puetz , Kurt Kremer , Ralf Everaers

Disordered filamentous networks with compliant crosslinks exhibit a low linear elastic shear modulus at small strains, but stiffen dramatically at high strains. Experiments have shown that the elastic modulus can increase by up to three…

We present a theoretical framework for the linear and nonlinear visco-elastic properties of reversibly crosslinked networks of semiflexible polymers. In contrast to affine models where network strain couples to the polymer end-to-end…

软凝聚态物质 · 物理学 2016-07-06 Jan Plagge , Andreas Fischer , Claus Heussinger

When sheared, most elastic solids such as metals, rubbers and polymer hydrogels dilate in the direction perpendicular to the shear plane. This well-known behaviour known as the Poynting effect is characterized by a positive normal stress.…

Recent experiments have demonstrated that the nonlinear elasticity of in vitro networks of the biopolymer actin is dramatically altered in the presence of a flexible cross-linker such as the abundant cytoskeletal protein filamin. The basic…

软凝聚态物质 · 物理学 2015-05-13 C. P. Broedersz , C. Storm , F. C. MacKintosh

Filamentous bio-materials such as fibrin or collagen networks exhibit an enormous stiffening of their elastic moduli upon large deformations. This pronounced nonlinear behavior stems from a significant separation between the stiffnesses…

软凝聚态物质 · 物理学 2019-05-21 Robbie Rens , Carlos Villarroel , Gustavo Düring , Edan Lerner

We study the mechanical stiffening behavior in two-dimensional (2D) cross-linked networks of semiflexible biopolymer filaments under simple shear. Filamental constituents immersed in a fluid undergo thermally excited bending motions.…

生物物理 · 物理学 2007-05-23 T. Van Dillen , P. R. Onck , E. Van der Giessen

Disordered networks of semiflexible filaments are common support structures in biology. Familiar examples include fibrous matrices in blood clots, bacterial biofilms, and essential components of cells and tissues of plants, animals, and…

软凝聚态物质 · 物理学 2023-09-28 Saamiya Syed , Fred C. MacKintosh , Jordan L. Shivers

Biopolymer networks from the intracellular to tissue scale display high rigidity and tensile stress while having coordinations well below the normal threshold for mechanical rigidity. The elastic filaments in these networks are often…

软凝聚态物质 · 物理学 2024-11-15 Marco Aurelio Galvani Cunha , John C. Crocker , Andrea J. Liu

We present a theory for the elasticity of cross-linked stiff polymer networks. Stiff polymers, unlike their flexible counterparts, are highly anisotropic elastic objects. Similar to mechanical beams stiff polymers easily deform in bending,…

软凝聚态物质 · 物理学 2007-11-26 C. Heussinger , B. Schaefer , E. Frey

We develop a continuum theory for equilibrium elasticity of a network of crosslinked semiflexible filaments, spanning the full range between flexible entropy-driven chains to stiff athermal rods. We choose the 3-chain constitutive model…

软凝聚态物质 · 物理学 2016-07-12 Fanlong Meng , Eugene M. Terentjev

Networks of filamentous proteins play a crucial role in cell mechanics. These cytoskeletal networks, together with various crosslinking and other associated proteins largely determine the (visco)elastic response of cells. In this letter we…

无序系统与神经网络 · 物理学 2009-11-10 D. A. Head , A. J. Levine , F. C. MacKintosh

Disordered athermal biopolymer materials, such as collagen networks that constitute a major component in extracellular matrices and various connective tissues, are initially soft and compliant but stiffen dramatically under strain. Such…

软凝聚态物质 · 物理学 2025-09-19 Zibin Zhang , Eran Bouchbinder , Edan Lerner

Unlike most synthetic materials, biological materials often stiffen as they are deformed. This nonlinear elastic response, critical for the physiological function of some tissues, has been documented since at least the 19th century, but the…

软凝聚态物质 · 物理学 2009-11-10 Cornelis Storm , Jennifer J. Pastore , Fred C. MacKintosh , Tom C. Lubensky , Paul A. Janmey

Collagen is the main structural and load-bearing element of various connective tissues, where it forms the extracellular matrix that supports cells. It has long been known that collagenous tissues exhibit a highly nonlinear stress-strain…

We study the elasticity of fibrous materials composed of generalized stiff polymers. It is shown that in contrast to cellular foam-like structures affine strain fields are generically unstable. Instead, a subtle interplay between the…

软凝聚态物质 · 物理学 2007-05-23 Claus Heussinger , Erwin Frey

The mechanics of disordered fibrous networks such as those that make up the extracellular matrix are strongly dependent on the local connectivity or coordination number. For biopolymer networks this coordination number is typically between…

软凝聚态物质 · 物理学 2019-05-01 Sadjad Arzash , Jordan L. Shivers , Albert J. Licup , Abhinav Sharma , Fred C. MacKintosh
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