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We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals…

种群与进化 · 定量生物学 2012-02-14 Artem S. Novozhilov

In this paper we elaborate on homogeneous and heterogeneous SIR-type epidemiological models. We find an unexpected correspondence between the epidemic trajectory of a transmissible disease in a homogeneous SIR-type model and radial null…

种群与进化 · 定量生物学 2023-08-04 Silke Klemm , Lucrezia Ravera

Individual contributions to the spread of an epidemic vary widely due to an individual's location in a social network and their intrinsic ability to spread or contract diseases. While the effect of heterogeneous population structure and…

种群与进化 · 定量生物学 2026-05-14 Abhay Gupta , Nicholas W. Landry

Most epidemic models assume equal mixing among members of a population. An alternative approach is to model a population as random network in which individuals may have heterogeneous connectivity. This paper builds on previous research by…

物理与社会 · 物理学 2007-05-23 Erik Volz

The study of social networks, and in particular the spread of disease on networks, has attracted considerable recent attention in the physics community. In this paper, we show that a large class of standard epidemiological models, the…

统计力学 · 物理学 2009-11-07 M. E. J. Newman

We study a well mixed SIR epidemic model with heterogeneous susceptibility and infectivity, allowing for an arbitrary joint distribution of these traits. Using an exact final size formulation and a branching process approximation for early…

种群与进化 · 定量生物学 2026-01-06 Mohamed El Khalifi

The ability to actually implement epidemic models is a crucial stake for public institutions, as they may be overtaken by the increasing complexity of current models and sometimes tend to revert to less elaborate models such as the SIR. In…

物理与社会 · 物理学 2023-12-19 Louis Bremaud , Olivier Giraud , Denis Ullmo

We formulate a general SEIR epidemic model in a heterogenous population characterized by some trait in a discrete or continuous subset of a space R d. The incubation and recovery rates governing the evolution of each homogenous…

偏微分方程分析 · 数学 2023-03-03 Luís Almeida , Pierre-Alexandre Bliman , Grégoire Nadin , Benoît Perthame , Nicolas Vauchelet

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

物理与社会 · 物理学 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

Human behavior plays a critical role in shaping epidemic trajectories. During health crises, people respond in diverse ways in terms of self-protection and adherence to recommended measures, largely reflecting differences in how individuals…

物理与社会 · 物理学 2026-01-30 Fabio Mazza , Gabriele Ricci , Francesca Colaiori , Stefano Guarino , Sandro Meloni , Fabio Saracco

We consider an epidemic model of SIR type set on a homogeneous tree and investigate the spreading properties of the epidemic as a function of the degree of the tree, the intrinsic basic reproduction number and the strength of the…

偏微分方程分析 · 数学 2021-06-09 Christophe Besse , Grégory Faye

In many epidemiological models a nonlinear transmission function is used in the form of power law relationship. It is constantly argued that such form reflects population heterogeneities including differences in the mixing pattern,…

种群与进化 · 定量生物学 2008-09-10 Artem S. Novozhilov

We generalize the Susceptible-Infected-Removed model for epidemics to take into account generic effects of heterogeneity in the degree of susceptibility to infection in the population. We introduce a single new parameter corresponding to a…

种群与进化 · 定量生物学 2021-01-27 Jonas Neipel , Jonathan Bauermann , Stefano Bo , Tyler Harmon , Frank Jülicher

Population heterogeneity is a key factor in epidemic dynamics, influencing both transmission and final epidemic size. While heterogeneity is often modelled through age structure, spatial location, or contact patterns, differences in host…

种群与进化 · 定量生物学 2026-01-26 Tamás Tekeli , Andrea Pugliese , Cinzia Soresina

We investigate final outcome properties of an SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a population of large sub-communities in which there is stronger disease transmission within the communities than…

概率论 · 数学 2024-04-08 Frank Ball , David Sirl , Pieter Trapman

This work is concerned with epidemiological models defined on networks, which highlight the prominent role of the social contact network of a given population in the spread of infectious diseases. In particular, we address the modelling and…

数值分析 · 数学 2023-03-07 Giovanni Naldi , Giuseppe Patane'

Since 1927, until recently, models describing the spread of disease have mostly been of the SIR-compartmental type, based on the assumption that populations are homogeneous and well-mixed. The focus of these models have typically been on…

物理与社会 · 物理学 2014-07-23 Lara Goscé , David A W Barton , Anders Johansson

We investigate the long-time dynamics of a SIR epidemic model in the case of a population of pathogens infecting a homogeneous host population. The pathogen population is structured by a genotypic variable. When the initial mass of the…

动力系统 · 数学 2023-06-05 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette

The SIR-compartment model is among the simplest models that describe the spread of a disease through a population. The model makes the unrealistic assumption that the population through which the disease is spreading is well-mixed. Although…

种群与进化 · 定量生物学 2022-11-16 Ryan Wilkinson , Marcus Roper

Epidemic models currently play a central role in our attempts to understand and control infectious diseases. Here, we derive a model for the diffusion limit of stochastic susceptible-infectious-removed (SIR) epidemic dynamics on a…

种群与进化 · 定量生物学 2013-09-30 Matthew Graham , Thomas House
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