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Comparative and evolutive ecologists are interested in the distribution of quantitative traits among related species. The classical framework for these distributions consists of a random process running along the branches of a phylogenetic…

应用统计 · 统计学 2017-08-24 Paul Bastide , Mahendra Mariadassou , Stéphane Robin

Species tree reconstruction from genomic data is increasingly performed using methods that account for sources of gene tree discordance such as incomplete lineage sorting. One popular method for reconstructing species trees from unrooted…

种群与进化 · 定量生物学 2017-12-06 Shubhanshu Shekhar , Sebastien Roch , Siavash Mirarab

A metric phylogenetic tree relating a collection of taxa induces weighted rooted triples and weighted quartets for all subsets of three and four taxa, respectively. New intertaxon distances are defined that can be calculated from these…

种群与进化 · 定量生物学 2020-02-12 Samaneh Yourdkhani , John A. Rhodes

Reticulate evolutionary processes result in phylogenetic histories that cannot be modeled using a tree topology. Here, we apply methods from topological data analysis to molecular sequence data with reticulations. Using a simple example, we…

定量方法 · 定量生物学 2015-11-05 Kevin Emmett , Raul Rabadan

The reconstruction of phylogenetic trees from mixed populations has become important in the study of cancer evolution, as sequencing is often performed on bulk tumor tissue containing mixed populations of cells. Recent work has shown how to…

数据结构与算法 · 计算机科学 2016-04-12 Mohammed El-Kebir , Gryte Satas , Layla Oesper , Benjamin J. Raphael

When estimating a phylogeny from a multiple sequence alignment, researchers often assume the absence of recombination. However, if recombination is present, then tree estimation and all downstream analyses will be impacted, because…

统计方法学 · 统计学 2014-10-08 Peter B. Chi , Sujay Chattopadhyay , Philippe Lemey , Evgeni V. Sokurenko , Vladimir N. Minin

Pairwise ordered tree alignment are combinatorial objects that appear in RNA secondary structure comparison. However, the usual representation of tree alignments as supertrees is ambiguous, i.e. two distinct supertrees may induce identical…

定量方法 · 定量生物学 2016-03-08 Cedric Chauve , Julien Courtiel , Yann Ponty

Given natural limitations on the length DNA sequences, designing phylogenetic reconstruction methods which are reliable under limited information is a crucial endeavor. There have been two approaches to this problem: reconstructing partial…

数据结构与算法 · 计算机科学 2008-12-10 Radu Mihaescu , Cameron Hill , Satish Rao

We consider the following basic problem in phylogenetic tree construction. Let $\mathcal{P} = \{T_1, \ldots, T_k\}$ be a collection of rooted phylogenetic trees over various subsets of a set of species. The tree compatibility problem asks…

数据结构与算法 · 计算机科学 2015-10-28 Yun Deng , David Fernández-Baca

Background: The reconstruction of the phylogenetic tree topology of four taxa is, still nowadays, one of the main challenges in phylogenetics. Its difficulties lie in considering not too restrictive evolutionary models, and correctly…

种群与进化 · 定量生物学 2014-06-19 Esther Ibáñez , Marta Casanellas

Phylogenetic trees are a central tool in understanding evolution. They are typically inferred from sequence data, and capture evolutionary relationships through time. It is essential to be able to compare trees from different data sources…

种群与进化 · 定量生物学 2017-10-31 Michelle Kendall , Caroline Colijn

Suppose we have a set $X$ consisting of $n$ taxa and we are given information from $k$ loci from which to construct a phylogeny for $X$. Each locus offers information for only a fraction of the taxa. The question is whether this data…

数据结构与算法 · 计算机科学 2020-02-25 Ghazaleh Parvini , Katherine Braught , David Fernández-Baca

Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of non-treelike evolutionary events, like recombination, hybridization, or lateral gene transfer. In this paper, we present and study a new…

种群与进化 · 定量生物学 2007-08-28 Gabriel Cardona , Francesc Rossello , Gabriel Valiente

Phylogenetic trees and networks are graphs used to model evolutionary relationships, with trees representing strictly branching histories and networks allowing for events in which lineages merge, called reticulation events. While the…

种群与进化 · 定量生物学 2026-04-17 Martin Frohn , Niels Holtgrefe , Leo van Iersel , Mark Jones , Steven Kelk

CRISPR technology has enabled large-scale cell lineage tracing for complex multicellular organisms by mutating synthetic genomic barcodes during organismal development. However, these sophisticated biological tools currently use ad-hoc and…

定量方法 · 定量生物学 2019-04-02 Jean Feng , William S DeWitt , Aaron McKenna , Noah Simon , Amy Willis , Frederick A Matsen

36 single genes of six plants inferred 18 unique trees using maximum parsimony. Such incongruence is an important issue and how to reconstruct the congruent tree still is one of the most challenges in molecular phylogenetics. For resolving…

基因组学 · 定量生物学 2007-05-23 Yunfeng Shan

Gene tree/species tree reconciliation is a recent decisive progress in phylo-genetic methods, accounting for the possible differences between gene histories and species histories. Reconciliation consists in explaining these differences by…

定量方法 · 定量生物学 2017-10-05 Damir Hasic , Eric Tannier

Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined and there exist multiple methods for…

种群与进化 · 定量生物学 2016-08-10 Nikita Alexeev , Max A. Alekseyev

Phylogenetic trees canonically arise as embeddings of phylogenetic networks. We recently showed that the problem of deciding if two phylogenetic networks embed the same sets of phylogenetic trees is computationally hard, \blue{in…

组合数学 · 数学 2021-04-13 Janosch Doecker , Simone Linz , Charles Semple

We study the problem of learning a node-labeled tree given independent traces from an appropriately defined deletion channel. This problem, tree trace reconstruction, generalizes string trace reconstruction, which corresponds to the tree…

计算复杂性 · 计算机科学 2020-09-22 Sami Davies , Miklos Z. Racz , Cyrus Rashtchian