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Scanning transmission electron microscopy (STEM) has advanced rapidly in the last decade thanks to the ability to correct the major aberrations of the probe forming lens. Now atomic-sized beams are routine, even at accelerating voltages as…

Determining the three-dimensional structure of proteins and protein complexes at atomic resolution is a fundamental task in structural biology. Over the last decade, remarkable progress has been made using "single particle" cryo-electron…

数值分析 · 数学 2017-06-05 Alex Barnett , Leslie Greengard , Andras Pataki , Marina Spivak

Super-resolution microscopy has revolutionized the imaging of complex physical and biological systems by surpassing the Abbe diffraction limit. Recent advancements, particularly in single-molecule localization microscopy (SMLM), have pushed…

The visual observation and tracking of cells and other micrometer-sized objects has many different biomedical applications. The automation of those tasks based on computer methods helps in the evaluation of such measurements. In this work,…

计算机视觉与模式识别 · 计算机科学 2014-12-04 Alexandra Heidsieck

There is a clear need for developments in characterisation techniques that provide detailed information about structure-function relationships in biology. Using electron microscopy to achieve high resolution while maintaining a broad field…

定量方法 · 定量生物学 2023-09-12 Chen Huang , Judy S. Kim , Angus I. Kirkland

The full understanding of cellular functions requires information about protein numbers for various biomolecular assemblies and their dynamics, which can be partly accessed by super-resolution fluorescence microscopy. Yet, many protein…

生物物理 · 物理学 2020-06-17 Kristin S. Grußmayer , Klaus Yserentant , Dirk-Peter Herten

We revisit the volume Green's function integral equation for modelling light scattering with discretization strategies as well as numerical integration recipes borrowed from finite element method. The merits of introducing finite element…

光学 · 物理学 2019-06-26 Wen Li , Dong Tan , Jing Xu , Shubo Wang , Yuntian Chen

The real-world implementation of materials prediction algorithms remains limited by persistent characterization bottlenecks in materials discovery, where photon-based probe techniques (e.g., XRD or Raman) impose long acquisition times and…

This paper introduces a Bayesian image segmentation algorithm based on finite mixtures. An EM algorithm is developed to estimate parameters of the Gaussian mixtures. The finite mixture is a flexible and powerful probabilistic modeling tool.…

计算机视觉与模式识别 · 计算机科学 2012-04-10 Mohamed Ali Mahjoub , karim kalti

This paper proposes a probabilistic approach for the detection and the tracking of particles in fluorescent time-lapse imaging. In the presence of a very noised and poor-quality data, particles and trajectories can be characterized by an a…

计算机视觉与模式识别 · 计算机科学 2017-04-04 Mariella Dimiccoli , Jean-Pascal Jacob , Lionel Moisan

Detecting structures at the particle scale within plastically deformed crystalline materials allows a better understanding of the occurring phenomena. While previous approaches mostly relied on applying hand-chosen criteria on different…

材料科学 · 物理学 2024-05-15 Armand Barbot , Riccardo Gatti

Super-resolution localization microscopy is based on determining the positions of individual fluorescent markers in a sample. The major challenge in reaching an ever higher localization precision lies in the limited number of collected…

光学 · 物理学 2020-08-05 Daniel Böning , Franz-Ferdinand Wieser , Vahid Sandoghdar

Cryo-electron microscopy (cryo-EM) is an emerging experimental method to characterize the structure of large biomolecular assemblies. Single particle cryo-EM records 2D images (so-called micrographs) of projections of the three-dimensional…

应用统计 · 统计学 2013-12-02 Mikhail Langovoy , Michael Habeck , Bernhard Schoelkopf

The ionic bonding across the lattice and ordered microscopic structures endow crystals with unique symmetry and determine their macroscopic properties. Unconventional crystals, in particular, exhibit non-traditional lattice structures or…

材料科学 · 物理学 2024-11-04 Hongyi Wang , Ji Sun , Jinzhe Liang , Li Zhai , Zitian Tang , Zijian Li , Wei Zhai , Xusheng Wang , Weihao Gao , Sheng Gong

Automated per-instance algorithm selection and configuration have shown promising performances for a number of classic optimization problems, including satisfiability, AI planning, and TSP. The techniques often rely on a set of features…

神经与进化计算 · 计算机科学 2020-10-01 Tome Eftimov , Gorjan Popovski , Quentin Renau , Peter Korosec , Carola Doerr

A method for photon linear polarization determination based on the measurement of the asymmetry of pairs produced by polarized photons in single crystals within the optimal intervals of pair particles energies is proposed. In difference to…

高能物理 - 实验 · 物理学 2009-10-31 A. B. Apyan , R. O. Avakian , S. M. Darbinian , K. A. Ispirian , S. P. Taroian

In this work, we propose a new paradigm of iterative model-based reconstruction algorithms for providing real-time solution for zooming-in and refining a region of interest in medical and clinical tomographic images. This algorithmic…

图像与视频处理 · 电气工程与系统科学 2025-12-01 Junqi Tang , Guixian Xu , Jinglai Li

The article demonstrates some less known principles of image build-up in diffractive microscopy and their usage in analysis unravelling the smallest localized information about the original object - an electromagnetic centroid. In…

医学物理 · 物理学 2016-12-15 Renata Rychtarikova , Georg Steiner , Michael B. Fischer , Dalibor Stys

Order parameters based on spherical harmonics and Fourier coefficients already play a significant role in condensed matter research in the context of systems of spherical or point particles. Here, we extend these types of order parameter to…

软凝聚态物质 · 物理学 2010-12-22 Aaron S. Keys , Christopher R. Iacovella , Sharon C. Glotzer

Liquid crystals (LCs) form an extremely rich range of self-assembled topological structures with artificially or naturally created topological defects. Some of the main applications of LCs are various optical and photonic devices, where…

光学 · 物理学 2023-03-09 Miha Papič , Urban Mur , Miha Ravnik , Igor Muševič , Matjaž Humar