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We wish to minimize the resources used for network coding while achieving the desired throughput in a multicast scenario. We employ evolutionary approaches, based on a genetic algorithm, that avoid the computational complexity that makes…

网络与互联网体系结构 · 计算机科学 2016-11-15 Minkyu Kim , Muriel Medard , Varun Aggarwal , Una-May O'Reilly , Wonsik Kim , Chang Wook Ahn , Michelle Effros

We present an analytically solvable model for self-assembly of a molecular complex on a filament. The process is driven by a seed molecule that undergoes facilitated diffusion, which is a search strategy that combines diffusion in…

统计力学 · 物理学 2015-11-04 Ziya Kalay

The genetic blueprint for the essential functions of life is encoded in DNA, which is translated into proteins -- the engines driving most of our metabolic processes. Recent advancements in genome sequencing have unveiled a vast diversity…

神经与进化计算 · 计算机科学 2024-06-12 James S. L. Browning , Daniel R. Tauritz , John Beckmann

Branched junction molecule assembly of DNA nanostructures, pioneered by Seeman's laboratory in the 1980s, has become increasingly sophisticated, as have the assembly targets. A critical design step is finding minimal sets of branched…

We investigate the possibility of encoding multiple solutions of a problem in a single chromosome. The best solution encoded in an individual will represent (will provide the fitness of) that individual. In order to obtain some benefits the…

神经与进化计算 · 计算机科学 2021-10-22 Mihai Oltean

The self-assembly of DNA-coated colloids controlled by enzymatic reactions has the potential to enable the formation of materials with hierarchical organization and switchable configurations. However, the problem of designing such…

We study theoretically a new generic scheme of programmable self-assembly of nanoparticles into clusters of desired geometry. The problem is motivated by the feasibility of highly selective DNA-mediated interactions between colloidal…

软凝聚态物质 · 物理学 2009-11-11 Nicholas A. Licata , Alexei V. Tkachenko

This review article discusses some common enhanced sampling methods in relation to the process of self-assembly of biomolecules. An introduction to self-assembly and its challenges is covered followed by a brief overview of the methods and…

软凝聚态物质 · 物理学 2025-03-03 Mason Hooten , Het Patel , Yiwei Shao , Rishabh Kumar Singh , Meenakshi Dutt

One of the main properties of biological systems is modularity, which manifests itself at all levels of their organization, starting with the level of molecular genetics, ending with the level of whole organisms and their communities. In a…

神经与进化计算 · 计算机科学 2018-11-20 Anton Eremeev , Alexander Spirov

Lots of bio-inspired research works have been conducted in self-adaptive software. They have focused on the external behavior of biological entities without their genetic material that causes this behavior and constitutes the challenge this…

软件工程 · 计算机科学 2019-04-30 Enas Nafar , Said Ghoul

In materials science, the challenge of rapid prototyping materials with desired properties often involves extensive experimentation to find suitable microstructures. Additionally, finding microstructures for given properties is typically an…

机器学习 · 计算机科学 2024-05-22 Sébastien Bompas , Stefan Sandfeld

Harnessing the intrinsic dynamics of physical systems for information processing opens new avenues for computation embodied in matter. Using simulations of a model system, we show that assemblies of DNA tiles capable of self-organizing into…

软凝聚态物质 · 物理学 2025-10-23 Tim E. Veenstra , René van Roij , Marjolein Dijkstra

A primary motivation for our research in digital ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…

神经与进化计算 · 计算机科学 2009-10-06 G. Briscoe , P. De Wilde

Recent generative models can synthesize "views" of artificial images that mimic real-world variations, such as changes in color or pose, simply by learning from unlabeled image collections. Here, we investigate whether such views can be…

计算机视觉与模式识别 · 计算机科学 2021-04-30 Lucy Chai , Jun-Yan Zhu , Eli Shechtman , Phillip Isola , Richard Zhang

Over the past 30 years many researchers in the field of evolutionary computation have put a lot of effort to introduce various approaches for solving hard problems. Most of these problems have been inspired by major industries so that…

神经与进化计算 · 计算机科学 2016-06-23 Mohammad Reza Bonyadi , Zbigniew Michalewicz , Frank Neumann , Markus Wagner

The capacity to adapt can greatly influence the success of systems that need to compensate for damaged parts, learn how to achieve robust performance in new environments, or exploit novel opportunities that originate from new technological…

适应与自组织系统 · 物理学 2011-12-15 James Whitacre , Axel Bender

De novo assembly is the process of reconstructing the genome sequence of an organism from sequencing reads. Genome sequences are essential to biology, and assembly has been a central problem in bioinformatics for four decades. Until…

基因组学 · 定量生物学 2023-08-16 Heng Li , Richard Durbin

Genetic algorithms, computer programs that simulate natural evolution, are increasingly applied across many disciplines. They have been used to solve various optimisation problems from neural network architecture search to strategic games,…

神经与进化计算 · 计算机科学 2021-09-14 Aymeric Vie , Alissa M. Kleinnijenhuis , Doyne J. Farmer

Throughout the evolution of biological species on Earth, cells and organs have developed many complex structures and processes to ensure their interactions with individual chemical molecules (small and macromolecular) and nanoscale objects…

生物物理 · 物理学 2021-01-12 Kenneth A. Dawson

We prove that the abstract Tile Assembly Model (aTAM) of nanoscale self-assembly is intrinsically universal. This means that there is a single tile assembly system U that, with proper initialization, simulates any tile assembly system T.…

数据结构与算法 · 计算机科学 2012-04-10 David Doty , Jack H. Lutz , Matthew J. Patitz , Robert T. Schweller , Scott M. Summers , Damien Woods