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Phylogenetic mixture models, in which the sites in sequences undergo different substitution processes along the same or different trees, allow the description of heterogeneous evolutionary processes. As data sets consisting of longer…

种群与进化 · 定量生物学 2012-07-17 Elizabeth S. Allman , John A. Rhodes , Seth Sullivant

We address phylogenetic reconstruction when the data is generated from a mixture distribution. Such topics have gained considerable attention in the biological community with the clear evidence of heterogeneity of mutation rates. In our…

种群与进化 · 定量生物学 2007-05-23 Daniel Stefankovic , Eric Vigoda

The reconstruction of phylogenies from DNA or protein sequences is a major task of computational evolutionary biology. Common phenomena, notably variations in mutation rates across genomes and incongruences between gene lineage histories,…

概率论 · 数学 2012-11-30 Elchanan Mossel , Sebastien Roch

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

种群与进化 · 定量生物学 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

种群与进化 · 定量生物学 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

Phylogenetic mixture models are statistical models of character evolution allowing for heterogeneity. Each of the classes in some unknown partition of the characters may evolve by different processes, or even along different trees. The…

种群与进化 · 定量生物学 2010-11-19 John A. Rhodes , Seth Sullivant

For a model of molecular evolution to be useful for phylogenetic inference, the topology of evolutionary trees must be identifiable. That is, from a joint distribution the model predicts, it must be possible to recover the tree parameter.…

种群与进化 · 定量生物学 2011-11-09 Elizabeth S. Allman , John A. Rhodes

In molecular phylogeny, relationships among organisms are reconstructed using DNA or protein sequences and are displayed as trees. A linear increase in the number of sequences results in an exponential increase of possible trees. Thus,…

基因组学 · 定量生物学 2007-05-23 Kerstin Hoef-Emden

Phylogenetic networks represent evolutionary history of species and can record natural reticulate evolutionary processes such as horizontal gene transfer and gene recombination. This makes phylogenetic networks a more comprehensive…

种群与进化 · 定量生物学 2021-06-15 Remie Janssen , Pengyu Liu

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

种群与进化 · 定量生物学 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch

Molecular phylogeny has focused mainly on improving models for the reconstruction of gene trees based on sequence alignments. Yet, most phylogeneticists seek to reveal the history of species. Although the histories of genes and species are…

种群与进化 · 定量生物学 2013-11-05 Gergely J. Szöllosi , Eric Tannier , Vincent Daubin , Bastien Boussau

Reticulate evolutionary processes result in phylogenetic histories that cannot be modeled using a tree topology. Here, we apply methods from topological data analysis to molecular sequence data with reticulations. Using a simple example, we…

定量方法 · 定量生物学 2015-11-05 Kevin Emmett , Raul Rabadan

The reconstruction of a species tree from genomic data faces a double hurdle. First, the (gene) tree describing the evolution of each gene may differ from the species tree, for instance, due to incomplete lineage sorting. Second, the…

种群与进化 · 定量生物学 2021-12-07 Sebastien Roch , Mike Steel

Phylogeny can be inferred using two sources of data from an organism: morphological data and molecular data. Historically, phylogenies were usually inferred using morphological characters, but some morphological features may not necessarily…

种群与进化 · 定量生物学 2023-12-19 Ray Han

Phylogenetic trees describe the evolutionary history of a group of present-day species from a common ancestor. These trees are typically reconstructed from aligned DNA sequence data. In this paper we analytically address the following…

种群与进化 · 定量生物学 2008-07-14 Mike Steel , Laszlo Szekely , Elchanan Mossel

Phylogenetic reconstruction aims at finding plausible hypotheses of the evolutionary history of genes or species based on genomic sequence information. The distinction of orthologous genes (genes that having a common ancestry and diverged…

种群与进化 · 定量生物学 2016-02-29 Marc Hellmuth , Nicolas Wieseke

Phylogenetic networks are increasingly used in evolutionary biology to represent the history of species that have undergone reticulate events such as horizontal gene transfer, hybrid speciation and recombination. One of the most fundamental…

种群与进化 · 定量生物学 2016-10-07 Philippe Gambette , Leo van Iersel , Steven Kelk , Fabio Pardi , Celine Scornavacca

The ongoing explosion of genome sequence data is transforming how we reconstruct and understand the histories of biological systems. Across biological scales, from individual cells to populations and species, trees-based models provide a…

种群与进化 · 定量生物学 2025-12-08 Yun Deng , Shing H. Zhan , Yulin Zhang , Chao Zhang , Bingjie Chen

Phylogenetic data arising on two possibly different tree topologies might be mixed through several biological mechanisms, including incomplete lineage sorting or horizontal gene transfer in the case of different topologies, or simply…

种群与进化 · 定量生物学 2009-12-18 Elizabeth S. Allman , Sonja Petrović , John A. Rhodes , Seth Sullivant

Estimating phylogenetic trees is an important problem in evolutionary biology, environmental policy and medicine. Although trees are estimated, their uncertainties are discarded by mathematicians working in tree space. Here we explicitly…

统计方法学 · 统计学 2017-10-16 Amy D. Willis , Rayna C. Bell
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