种群与进化
It is well known that the confirmed COVID-19 infection is only a fraction of the true fraction. In this paper we use an artificial neural network to learn the connection between the confirmed infection count, the testing data, and the true…
In this article, we have considered a planar slow-fast modified Leslie-Gower predator-prey model with a weak Allee effect in the predator, based on the natural assumption that the prey reproduces far more quickly than the predator. We…
The honeybee plays an extremely important role in ecosystem stability and diversity and in the production of bee pollinated crops. Honey bees and other pollinators are under threat from the combined effects of nutritional stress,…
Genotype-to-phenotype mappings translate genotypic variations such as mutations into phenotypic changes. Neutrality is the observation that some mutations do not lead to phenotypic changes. Studying the search trajectories in genotypic and…
Natural ecosystems, in particular on the microbial scale, are inhabited by a large number of species. The population size of each species is affected by interactions of individuals with each other and by spatial and temporal changes in…
An epidemiological study of deaths is carried out in a dozen countries by analyzing the first wave of the COVID-19 pandemic. These countries are among those most affected by the first wave, i.e. where daily-death data series may closely…
Species-rich communities, such as the microbiota or microbial ecosystems, provide key functions for human health and climatic resilience. Increasing effort is being dedicated to design experimental protocols for selecting community-level…
Historical sciences like evolutionary biology reconstruct past events by using the traces that the past has bequeathed to the present. The Markov Chain Convergence Theorem and the Data Processing Inequality describe how the mutual…
The onset of the COVID-19 pandemic drove a widespread, often uncoordinated effort by research groups to develop mathematical models of SARS-CoV-2 to study its spread and inform control efforts. The urgent demand for insight at the outset of…
Ocean acidification, a direct consequence of increased carbon dioxide (CO2) emissions, has emerged as a critical area of concern within the scientific community. The world's oceans absorb approximately one-third of human-caused CO2…
A number of theoretical models have been developed in recent years modelling epidemic spread in educational settings such as universities to help inform re-opening strategies during the Covid-19 pandemic. However, these studies have had…
This paper introduces an innovative model for infectious diseases in predator-prey populations. We not only prove the existence of global non-negative solutions but also establish essential criteria for the system's decline and…
Human activity is leading to changes in the mean and variability of climatic parameters in most locations around the world. The changing mean has received considerable attention from scientists and climate policy makers. However, recent…
From 08-12 August, 2022, 32 individuals participated in a workshop, Stability and Fluctuations in Complex Ecological Systems, at the Lorentz Center, located in Leiden, The Netherlands. An interdisciplinary dialogue between ecologists,…
Experimental work suggests that biological soil crusts, dominant primary producers in drylands and tundra, are particularly vulnerable to disturbances that cause reverse ecological succession. To model successional transitions in biocrust…
Tumor heterogeneity is a complex and widely recognized trait that poses significant challenges in developing effective cancer therapies. In particular, many tumors harbor a variety of subpopulations with distinct therapeutic response…
The quality of the inferences we make from pathogen sequence data is determined by the number and composition of pathogen sequences that make up the sample used to drive that inference. However, there remains limited guidance on how to best…
The mechanisms underlying lifespan evolution in organisms have long been mysterious. However, recent studies have demonstrated that organisms evolutionarily gain noncoding RNAs (ncRNAs) that carry endogenous profound functions in higher…
Pathogens drive changes in host immune systems that in turn exert pressure for pathogens to evolve. Quantifying and understanding this constant coevolutionary process has clear practical global health implications. Yet its relatively easier…
Uncertainty can be classified as either aleatoric (intrinsic randomness) or epistemic (imperfect knowledge of parameters). The majority of frameworks assessing infectious disease risk consider only epistemic uncertainty. We only ever…