神经元与认知
Existing studies have demonstrated significant sex differences in the neural mechanisms of daily life and neuropsychiatric disorders. The hierarchical organization of the functional brain network is a critical feature for assessing these…
Diffusion MRI is a powerful tool that serves as a bridge between brain microstructure and cognition. Recent advancements in cognitive neuroscience have highlighted the persistent challenge of understanding how individual differences in…
This study explores prosodic production in latent aphasia, a mild form of aphasia associated with left-hemisphere brain damage (e.g. stroke). Unlike prior research on moderate to severe aphasia, we investigated latent aphasia, which can…
Research question: This study aims to find whether other neurostructural measurements could be added and combined with the state-of-the-art Alzheimer's imaging marker called MSSM to improve sensitivity to neurodegeneration in Alzheimer's…
Function and dysfunctions of neural systems are tied to the temporal evolution of neural states. The current limitations in showing their causal role stem largely from the absence of tools capable of probing the brain's internal state in…
Firing across populations of neurons in many regions of the mammalian brain maintains a temporal memory, a neural timeline of the recent past. Behavioral results demonstrate that people can both remember the past and anticipate the future…
Animals learn to predict external contingencies from experience through a process of conditioning. A natural mechanism for conditioning is stimulus substitution, whereby the neuronal response to a stimulus with no prior behavioral…
Educational multimedia has become increasingly important in modern learning environments because of its cost-effectiveness and ability to overcome the temporal and spatial limitations of traditional methods. However, the complex cognitive…
Just like electrical engineers understand how microprocessors execute programs in terms of how transistor currents are affected by their inputs, neuroscientists want to understand behavior production in terms of how neuronal outputs are…
Abstract Objective In Genetic Absence Epilepsy Rats From Strasbourg ( GAERS s), epileptogenesis takes place during brain maturation and correlates with increased mRNA expression of D3 dopamine receptors (D3R). Whether these alterations are…
Studying influential nodes (I-nodes) in brain networks is of great significance in the field of brain imaging. Most existing studies consider brain connectivity hubs as I-nodes. However, this approach relies heavily on prior knowledge from…
We study the synchronisation of neurons in a realistic model under the Hodgkin-Huxley dynamics. To focus on the role of the different locations of the excitatory synapses, we use two identical neurons where the set of input signals is…
This work delves into studying the synchronization in two realistic neuron models using Hodgkin-Huxley dynamics. Unlike simplistic point-like models, excitatory synapses are here randomly distributed along the dendrites, introducing strong…
We study noisy calcium imaging data, with a focus on the classification of spike traces. As raw traces obscure the true temporal structure of neuron's activity, we performed a tuned filtering of the calcium concentration using two methods:…
The appearance of an object triggers an orienting gaze movement toward its location. The movement consists of a rapid rotation of the eyes, the saccade, which is accompanied by a head rotation if the target eccentricity exceeds the…
Neurophysiology research has demonstrated that it is possible and valuable to investigate sensory processing in scenarios involving continuous sensory streams, such as speech and music. Over the past 10 years or so, novel analytic…
Identical systems, or entities, are indistinguishable in quantum mechanics (QM), and the symmetrization postulate rules the possible statistical distributions of a large number of identical quantum entities. However, a thorough analysis on…
In visual decision making, high-level features, such as object categories, have a strong influence on choice. However, the impact of low-level features on behavior is less understood partly due to the high correlation between high- and…
Although the raison d'etre of the brain is the survival of the body, there are relatively few theoretical studies of closed-loop rhythmic motor control systems. In this paper we provide a unified framework, based on variational analysis,…
Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…