医学物理
Fractional flow reserve (FFR) is the gold standard for diagnosing coronary artery disease (CAD). FFRCT uses computational fluid dynamics (CFD) to evaluate FFR non-invasively by simulating coronary flow in geometries reconstructed from…
This work explores the use of Surface-Enhanced Raman Spectroscopy (SERS) combined with artificial neural network (ANN) models to detect and quantify growth hormone (GH) and testosterone (TE) in the blood of Sprague Dawley (SD) rats. SERS…
Equal access to health ensures that all citizens, regardless of socio-economic status, can achieve optimal health, leading to a more productive, equitable, and resilient society. Yet, migrant populations were frequently observed to have…
Detecting the specificity of cancer cells to distinguish them from normal ones is an important step in the general framework of cancer diagnosis. A routine example of such diagnosis in cancerous tissues implies using microscope analysis of…
Objective: Inclusion of individualised electrical conductivities of head tissues is crucial for the accuracy of electrical source imaging techniques based on electro/magnetoencephalography and the efficacy of transcranial electrical…
Background: FLASH radiotherapy is a treatment regime that delivers therapeutic dose to tumors at an ultra-high dose rate while maintaining adequate normal tissue sparing. However, a comprehensive understanding of the underlying mechanisms,…
Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with DECT leveraging advanced X-ray source and/or detector…
Objective: This paper introduces a novel PET imaging methodology called 3-dimensional positron imaging (3D{\pi}), which integrates total-body (TB) coverage, time-of-flight (TOF) technology, ultra-low dose imaging capabilities, and…
Molten corium stabilization following a severe accident is of crucial importance in order to ensure containment integrity on a long-term basis and minimizing radioactive elements releases outside the plant. Among the possible options,…
Autonomic nervous system is important for cardiac function regulation. Modeling of autonomic cardiac regulation can contribute to health tracking and disease management. This study proposed a mathematical model that simulates autonomic…
In this work, we investigate the effects of stent indentation on hemodynamic indicators in stented coronary arteries. Our aim is to assess in-silico risk factors for in-stent restenosis (ISR) and thrombosis after stent implantation. The…
Cardiac pulsation is a physiological confound of functional magnetic resonance imaging (fMRI) time-series that introduces spurious signal fluctuations in proximity to blood vessels. fMRI alone is not sufficiently fast to resolve cardiac…
Photoacoustic tomography (PAT) enables non-invasive cross-sectional imaging of biological tissues, but it fails to map the spatial variation of speed-of-sound (SOS) within tissues. While SOS is intimately linked to density and elastic…
Cervical cancer presents a significant global health challenge, necessitating advanced diagnostic and prognostic approaches for effective treatment. This paper investigates the potential of employing multi-modal medical imaging at various…
In this study, we proposed a universal n-th order partial differential equation (PDE) of 2-D Radon transform to disclose the relationship of Radon transform over a neighborhood of the integral line, named as local correlation equation…
Objectives: Evaluating the effects and artifacts introduced by medical foreign bodies in clinical dark-field chest radiographs and assessing their influence on the evaluation of pulmonary tissue, compared to conventional radiographs.…
We present a microstructure imaging technique for estimating compartment-specific T2 and T2* simultaneously in the human brain. Microstructure imaging with diffusion MRI (dMRI) has enabled the modelling of intra-neurite and extra-neurite…
Optical imaging of metabolism can provide key information about health and disease progression in cells and tissues, however, current methods have lacked gold-standard information about histological structure. Conversely, histology and…
Photoacoustic (PA) imaging has been widely applied in both preclinical and clinical applications. With a significantly increasing number of data acquisition channels, fast and high-quality image reconstruction for real-time PA imaging is an…
In tissue engineering, we seek to address comprehensive tissue repair and regeneration needs. Aligned nanofibers have emerged as powerful and versatile tools, attributable to their structural and biochemical congruence with the natural…