医学物理
At the onset of viral outbreaks, broad-spectrum antiviral materials are crucial before specific therapeutics become available. We report scalable, biodegradable black phosphorus (BP) hybrids that provide mutation-resilient virucidal…
Background: Accurate myocardial T1 mapping at 5T remains a technical challenge due to field inhomogeneity and prolonged T1 values. The aim of this study is to develop an accurate and clinically applicable myocardial T1 mapping technique for…
There has been recent interest in the use of magnitude-based fitting methods for estimating proton density fat fraction (PDFF) and R2* from chemical shift-encoded MRI (CSE-MRI) data, since these methods can still be used when complex- based…
KEY WORDS: Artificial Intelligence (AI), Theranostics, Dosimetry, Radiopharmaceutical Therapy (RPT), Patient-friendly dosimetry KEY POINTS - The rapid evolution of radiopharmaceutical therapy (RPT) highlights the growing need for…
As disease often alters the structural properties of soft tissue, noninvasive elastography techniques have emerged to quantitatively assess in vivo mechanical properties. Magnetic Resonance Elastography (MRE) based on dynamic deformations…
Radiation therapy treatment planning is an iterative, expertise-dependent process, and the growing burden of cancer cases has made reliance on manual planning increasingly unsustainable, underscoring the need for automation. In this study,…
Purpose: To identify a clinically interpretable subset of survival-relevant features in HN cancer using Bayesian Network (BN) and evaluate its prognostic and causal utility. Methods and Materials: We used the RADCURE dataset, consisting of…
Full Waveform Inversion (FWI) is a promising technique for achieving high-resolution imaging in medical ultrasound. However, conventional FWI methods suffer from issues related to computational efficiency, dependence on initial models, and…
Robust treatment planning algorithms for Intensity Modulated Proton Therapy (IMPT) and Intensity Modulated Radiation Therapy (IMRT) allow for uncertainty reduction in the delivered dose distributions through explicit inclusion of error…
Cardiopulmonary resuscitation (CPR) is one of the essential tools to ensure oxygen supply during cardiac arrest. However, the precise effects of chest compression are not quantifiable to this day. This often results in a low quality of…
Chronic wounds present a major challenge in elderly individuals due to diminished regenerative capacity and impaired tissue repair mechanisms associated with aging. In this study, we formulated a topical gel composed of zinc oxide (ZnO),…
Traditional ultrasound simulation methods solve wave equations numerically, achieving high accuracy but at substantial computational cost. Faster alternatives based on convolution with precomputed impulse responses remain relatively slow,…
Tumor Obliteration by Resonant Amplification (TOR) was evaluated purely in simulation. Forward models in COMSOL, ANSYS, and ABAQUS used the same small-strain rheology, nonthermal/noncavitational limits, and an emulated closed loop…
Transcranial photoacoustic computed tomography (PACT) is an emerging neuroimaging modality, but skull-induced aberrations can result in severe image artifacts if not compensated for during image reconstruction. The development of advanced…
The human nose exhibits a huge variation in shape among individuals. All these variants alter the airflow through the nasal cavity and can impact how we smell odors. To acquire a better understanding of physiological and pathological…
Cryosurgery employs a safe and relatively simple technique of exposure and is an advantageous and highly rated method. For its effective application, it is necessary to control both the volume of the expanding freezing zone and volumetric…
Expansion of diffusion MRI (dMRI) both into the realm of strong gradients, and into accessible imaging with portable low-field devices, brings about the challenge of gradient nonlinearities. Spatial variations of the diffusion gradients…
This study proposes a simple and practical approach based on in-vitro measurements and in-silico simulation using the likelihood-free Bayesian inference with the finite element method simultaneously for stochastic calibration and…
Laser-induced interstitial thermotherapy (LITT) is applied to ex-vivo porcine livers. An artificial blood vessel is used to study the cooling effect of larger blood vessels in proximity to the ablation zone. The same setting is simulated…
Parallel imaging is ubiquitous in MRI, enabling diverse applications such as ultra-high-resolution functional and quantitative imaging with greater temporal resolution or reduced scan times respectively. Successful unfolding is contingent…