医学物理
In a linear tomosynthesis scanner designed for imaging histologic samples of several centimeter size at 10 micrometer resolution, the mechanical instability of the scanning stage (+/-10 micrometers) exceeded the resolution of the image…
A hybrid imaging system consisting of a standard CT scanner and a low-profile photon-counting detector insert in contact with the patient's body has been used to produce ultrahigh-resolution images in a limited volume in chest scans of…
Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…
The aim of this study was to assess the extreme effects of tinted lenses on colour vision by examining changes in chromatic sensitivity when viewing visual displays through a slightly tinted (blue-blocking) filter and through a heavily…
Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…
Pump-probe microscopy of melanin in tumors has been proposed to improve diagnosis of malignant melanoma, based on the hypothesis that aggressive cancers disaggregate melanin structure. However, measured signals of melanin are complex…
This paper presents an efficient parallel radiative transfer-based inverse-problem solver for time-domain optical tomography. The radiative transfer equation provides a physically accurate model for the transport of photons in biological…
A conceptual design of a novel UVC-LED air-cleaner is presented as part of an international educational-research study. The main components are a dust-filter assembly, a UVC chamber and a fan. The dust-filter aims to suppress dust…
A stable shape for corneas experiencing refractive surgery has to be sustained so as to elude post-refractive surgery de-compensation. This de-compensation leads to visual complications and unsatisfactory procedure recovery. Variation in…
We present a flyscan compatible acquisition scheme for three-modal X-Ray Computed Tomography (CT) with two-dimensional phase sensitivity. Our approach is demonstrated using a "beam tracking" setup, through which a sample's attenuation,…
In this paper we propose a solution to the need for a fast particle transport algorithm in Online Adaptive Proton Therapy capable of cheaply, but accurately computing the changes in patient dose metrics as a result of changes in the system…
It is technically challenging to design efficient transceiver coil arrays for foot and ankle imaging at ultrahigh fields due to the irregular geometry of the anatomy. Shortened wavelength because of the high operation frequency at ultrahigh…
Tuberculosis (TB) is a contagious disease that causes 1.5 million deaths per year globally. Early diagnosis of TB patients is critical to control its spread. However, standard TB diagnostic tests such as sputum culture take days to weeks to…
The choice of appropriate boundary conditions is a crucial step in the development of cardiovascular models for blood flow simulations. The three-element Windkessel model is usually employed as a lumped boundary condition, providing a…
Two-dimensional (2D) materials have been used extensively in various fields due to their unique physical and chemical properties. Among their diverse applications, field-effect transistor biosensors (bio-FETs) promise a brilliant prospect…
In silico tissue models enable evaluating quantitative models of magnetic resonance imaging. This includes validating and sensitivity analysis of imaging biomarkers and tissue microstructure parameters. We propose a novel method to generate…
The concept of using kilovoltage (kV) and megavoltage (MV) beams concurrently has potential applications in cone beam computed tomography (CBCT) guided radiation therapy, such as single breath hold scans, metal artifact reduction, and…
Background and Objectives: In a significant portion of surgeries, blood pressure (BP) is often measured non-invasively in an intermittent manner. This practice has a risk of missing clinically relevant BP changes between two adjacent…
Ultra high dose rate electron beams also known as FLASH radiotherapy is becoming of importance in several preclinial cancer treatment studies. However, due to the dose rate used during the irradiation sessions, no real time dose monitoring…
Most ultrasound (US) imaging techniques use spatially-constant speed-of-sound (SoS) values for beamforming. Having a discrepancy between the actual and used SoS value leads to aberration artifacts, e.g., reducing the image resolution, which…