医学物理
Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…
In this study, two proton beam delivery designs, passive scattering proton therapy (PSPT) and pencil beam scanning (PBS), were quantitatively compared in terms of dosimetric indices. The GATE Monte Carlo code was used to simulate the proton…
Non-invasive imaging of deep blood vessels for mapping hemodynamics remains an open quest in biomedical optical imaging. Although pure optical imaging techniques offer rich optical contrast of blood and have been reported to measure blood…
Functional luminal imaging probe (FLIP) is used to measure cross-sectional area (CSA) and pressure at sphincters. It consists of a catheter surrounded by a fluid filled cylindrical bag, closed on both ends. Plotting the pressure-CSA…
Developing computational models of the human jaw acquired from cone-beam computed tomography (CBCT) scans is time-consuming and labor-intensive. Besides, a quantitative comparison is not attainable in the literature due to the involved…
Between 1966 and 1974, France conducted 41 atmospheric nuclear weapon tests in Polynesia. Radioactive fallout impacted downwind atolls and islands leading to the external and internal exposure of the local populations to ionizing radiation.…
Introduction: We developed and evaluated a method for dose calibration and monitoring under conventional and ultra-high dose rates for small animal experiments with small-field proton beams using a Faraday cup. Methods: We determined a…
Purpose: To evaluate changes in the anisotropic elastic properties of ex vivo human cornea treated with UV cross-linking (CXL) using non-contact acoustic micro-tapping Optical Coherence Elastography (AuT-OCE) Design: AuT performed on normal…
This document outlines a PROSPERO pre-registered protocol for a systematic review regarding articulatory changes in speech following oral or orophayrngeal cancer treatment. Treatment of tumours in the oral cavity may result in physiological…
The process of wound healing has been an active area of research around the world. The problem is the wounds of different patients heal differently. For example, patients with a background of diabetes may have difficulties in healing [1].…
Background: Computational fluid dynamics (CFD) is increasingly used to assess blood flow conditions in patients with congenital heart disease (CHD). This requires patient-specific anatomy, usually obtained from segmented 3D cardiovascular…
The RefleXion X1 is the first biology-guided radiotherapy (BgRT) system. Its dual 90-degree PET detector collects fewer pair production events compared to a full-ring diagnostic PET system. In the proposed BgRT workflow, a short scan is…
Filter-exchange imaging (FEXI) has already been utilized in several biomedical studies for evaluating the permeability of cell membranes. The method relies on suppressing the extracellular signal using strong diffusion weighting (the…
Background and purpose: The delineation of the gross tumor volume (GTV) is a critical step for radiation therapy treatment planning. The delineation procedure is typically performed manually which exposes two major issues: cost and…
Information about the structure and composition of biopsy specimens can assist in disease monitoring and diagnosis. In principle, this can be acquired from Raman and infrared (IR) hyperspectral images (HSIs) that encode information about…
This paper developed a seed-mediated synthesis of $\alpha$-Al$_2$O$_3$ by the combustion method using halloysite nanocrystals as seeds and analyzed the dosimetric characteristics of these samples, including radioluminescence (RL),…
An accurate planar visualization (curved planar reformation - CPR) of intracranial arteries is mandatory for an improved luminal and mural assessment especially in low resolution Magnetic Resonance Imaging (MRI) data sets acquired in…
In recent years high-resolution 3D printing has enabled a diverse range of new, low-cost, methods for ultrasonic wave-front shaping. Acoustic holograms, particularly, allow for the generation of arbitrary, diffraction limited, acoustic…
Optimization and uncertainty quantification have been playing an increasingly important role in computational hemodynamics. However, existing methods based on principled modeling and classic numerical techniques have faced significant…
The aim of this study was to investigate the influence of MRI and patient data on the prediction of knee osteoarthritis (OA) incidence using different deep learning architectures. Knee OA incidence within 24 months was predicted using the…