IBEX 成像知识库：促进免疫荧光成像方法采用与开发的社区资源
组织与器官
2025-10-14 v2 图像与视频处理
摘要
迭代漂白扩展多重性 (IBEX) 知识库是供采用 IBEX 及相关 2D 和 3D 免疫荧光成像方法的研究人员使用的中心门户。知识库的设计以开源软件社区的工作为蓝本，包含三个方面：开发平台 (GitHub)、静态网站和数据归档服务。该知识库通过为推荐和不推荐的试剂（如一抗和二抗）提供验证数据，促进了整个研究生命周期中的开放科学实践。除了报告阴性数据外，知识库还通过提供共享实验方案、视频、数据集、软件和出版物的场所，赋能方法的采用与发展。专门的讨论论坛在解决已发表论文中未涵盖的问题的同时，培养了研究人员之间的社区意识。通过这种方式，来自世界各地的科学家正以更快的速度推进科学发现，减少时间与精力的浪费，并使人们对所得数据产生更大的信心。
引用
@article{arxiv.2412.12965,
title = {The IBEX Imaging Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluoresence Imaging Methods},
author = {Ziv Yaniv and Ifeanyichukwu U. Anidi and Leanne Arakkal and Armando J. Arroyo-Mejías and Rebecca T. Beuschel and Katy Börner and Colin J. Chu and Beatrice Clark and Menna R. Clatworthy and Jake Colautti and Fabian Coscia and Joshua Croteau and Saven Denha and Rose Dever and Walderez O. Dutra and Sonja Fritzsche and Spencer Fullam and Michael Y. Gerner and Anita Gola and Kenneth J. Gollob and Jonathan M. Hernandez and Jyh Liang Hor and Hiroshi Ichise and Zhixin Jing and Danny Jonigk and Evelyn Kandov and Wolfgang Kastenmüller and Joshua F. E. Koenig and Aanandita Kothurkar and Rosa K. Kortekaas and Alexandra Y. Kreins and Ian T. Lamborn and Yuri Lin and Katia Luciano Pereira Morais and Aleksandra Lunich and Jean C. S. Luz and Ryan B. MacDonald and Chen Makranz and Vivien I. Maltez and John E. McDonough and Ryan V. Moriarty and Juan M. Ocampo-Godinez and Vitoria M. Olyntho and Annette Oxenius and Kartika Padhan and Kirsten Remmert and Nathan Richoz and Edward C. Schrom and Wanjing Shang and Lihong Shi and Rochelle M. Shih and Emily Speranza and Salome Stierli and Sarah A. Teichmann and Tibor Z. Veres and Megan Vierhout and Brianna T. Wachter and Adam K. Wade-Vallance and Margaret Williams and Nathan Zangger and Ronald N. Germain and Andrea J. Radtke},
journal= {arXiv preprint arXiv:2412.12965},
year = {2025}
}