非线性随机基因调控网络中的信号传播
分子网络
2007-05-23 v1 定量方法
摘要
通过研究随机非线性基因调控网络对输入信号发生器的响应，揭示了该网络的结构。详细研究了四个应用：两个线性系统的非线性连接、逻辑脉冲的设计、分子放大器以及 E2F1 调控元件中三个信号发生器的干涉。基因相互作用使用具有精确数学结构并保留过程生物学含义的分子图示呈现。
引用
@article{arxiv.q-bio/0510055,
title = {Signal Propagation in Nonlinear Stochastic Gene Regulatory Networks},
author = {Sever Achimescu and Ovidiu Lipan},
journal= {arXiv preprint arXiv:q-bio/0510055},
year = {2007}
}
备注
45 pages, 14 figures, Excerpts from this manuscript were presented at the 3rd International Conference on Pathways, Networks, and Systems: Theory and Experiments, October 2-7, Rhodes Greece 2005. A reduced version was submitted on May 24th 2005 to IEE Systems Biology. High quality figures at http://www.cbgm.mcg.edu/signal.pdf