Elastic Correlations in Nucleosomal DNA Structure
生物大分子
2009-11-13 v1 软凝聚态物质
摘要
The structure of DNA in the nucleosome core particle is studied using an elastic model that incorporates anisotropy in the bending energetics and twist-bend coupling. Using the experimentally determined structure of nucleosomal DNA [T.J. Richmond and C.A. Davey, Nature {\bf 423}, 145 (2003)], it is shown that elastic correlations exist between twist, roll, tilt, and stretching of DNA, as well as the distance between phosphate groups. The twist-bend coupling term is shown to be able to capture these correlations to a large extent, and a fit to the experimental data yields a new estimate of G=25 nm for the value of the twist-bend coupling constant.
引用
@article{arxiv.q-bio/0701014,
title = {Elastic Correlations in Nucleosomal DNA Structure},
author = {Farshid Mohammad-Rafiee and Ramin Golestanian},
journal= {arXiv preprint arXiv:q-bio/0701014},
year = {2009}
}