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Sliding is one of the fundamental mechanical movements in machinery. In macroscopic systems, double-rack pinion machines employ gears to slide two linear tracks along opposite directions. In microscopic systems, kinesin-5 proteins crosslink…

Biological Physics · Physics 2021-05-04 Maximilian J. Urban , Steffen Both , Chao Zhou , Anton Kuzyk , Klas Lindfors , Thomas Weiss , Na Liu

Enzymatic DNA labeling is a powerful tool with applications in biochemistry, molecular biology, biotechnology, medical science, and genomic research. This paper contributes to the evolving field of DNA-based data storage by presenting a…

Information Theory · Computer Science 2024-05-15 Daniella Bar-Lev , Tuvi Etzion , Eitan Yaakobi , Zohar Yakhini

A review of hollow core whispering gallery resonators (WGRs)is given. After a short introduction to the topic of whispering gallery resonators we provide a description of whispering gallery modes in hollow or liquid core WGRs. Next,…

Optics · Physics 2015-06-22 Jonathan M. Ward , Nitesh Dhasmana , Síle Nic Chormaic

Optical frequency conversion processes in nonlinear materials are limited in wavelength by the accessible phase matching and the required high pump powers. In this letter, we report a novel broadband phase matching (PM) technique in high…

Optics · Physics 2013-03-18 Guoping Lin , Josef U. Fürst , Dmitry V. Strekalov , Nan Yu

DNA read mapping is a ubiquitous task in bioinformatics, and many tools have been developed to solve the read mapping problem. However, there are two trends that are changing the landscape of readmapping: First, new sequencing technologies…

Genomics · Quantitative Biology 2017-02-09 Jens Quedenfeld , Sven Rahmann

Interactions between whispering gallery modes (WGMs) and small nanoparticles are commonly modelled by treating the particle as a point dipole scatterer. This approach is assumed to be accurate as long as the nanoparticle radius, $a$, is…

Engineered electromagnetic fields in plasmonic nanopores enable enhanced optical detection and their use in single molecule sequencing. Here, a plasmonic nanopore prepared in a thick nanoporous film is used to investigate the interaction…

DNA microarrays are a relatively new technology that can simultaneously measure the expression level of thousands of genes. They have become an important tool for a wide variety of biological experiments. One of the most common goals of DNA…

Methodology · Statistics 2013-07-02 Eric Bair

An early detection of different tumor subtypes is crucial for an effective guidance to personalized therapy. While much efforts focus on decoding the sequence of DNA basis to detect the genetic mutations related to cancer, it is becoming…

Genomic foundation models have the potential to decode DNA syntax, yet face a fundamental tradeoff in their input representation. Standard fixed-vocabulary tokenizers fragment biologically meaningful motifs such as codons and regulatory…

Monitoring the kinetics and conformational dynamics of single enzymes is crucial in order to better understand their biological functions as these motions and structural dynamics are usually unsynchronized among the molecules. Detecting the…

Biological Physics · Physics 2017-05-29 Eugene Kim , Martin D. Baaske , Isabel Schuldes , Peter S. Wilsch , Frank Vollmer

As generative AI achieves hyper-realism, superficial artifact detection has become obsolete. While prevailing methods rely on resource-intensive fine-tuning of black-box backbones, we propose that forgery detection capability is already…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Jingtong Dou , Chuancheng Shi , Yemin Wang , Shiming Guo , Anqi Yi , Wenhua Wu , Li Zhang , Fei Shen , Tat-Seng Chua

There are some issues with traditional whispering gallery mode (WGM) resonators like poor light extraction and a dense mode spectrum. In this paper we introduce a solution to these limitations by proposing open WGM (OWGM) resonators that…

Optics · Physics 2024-08-14 D. R. Kazanov , A. M. Monakhov

Solid-state nanopore and nanopipette sensors are powerful devices for the detection, quantification and structural analysis of biopolymers such as DNA and proteins, especially in carrier-enhanced resistive-pulse sensing. However, hundreds…

Mesoscale and Nanoscale Physics · Physics 2025-10-14 Cengiz J. Khan , Oliver J. Irving , Rand A. Al-Waqfi , Giorgio Ferrari , Tim Albrecht

Nonlinear optical processes in whispering gallery mode (WGM) microresonators have attracted much attention. Owing to the strong confinement of light in a small volume, a WGM microresonator can dramatically boost the strength of light field,…

Optics · Physics 2015-12-29 Jintian Lin , Yingxin Xu , Jielei Ni , Min Wang , Zhiwei Fang , Lingling Qiao , Wei Fang , Ya Cheng

We present a theoretical investigation of a whispering gallery mode (WGM) resonator coupled to a Mach-Zehnder interferometer (MZI) and show a bimodal coincidence transmission spectrum when the input state is an indistinguishable photon…

Quantum Physics · Physics 2024-04-29 Callum Jones , Antonio Vidiella-Barranco , Jolly Xavier , Frank Vollmer

Heller et. Al. (Science 311, 508 (2006)) demonstrated the first DNA-CN optical sensor by wrapping a piece of double-stranded DNA around the surface of single-walled carbon nanotubes (CN). This new type of optical device can be placed inside…

Mesoscale and Nanoscale Physics · Physics 2012-09-25 Anh D. Phan , Dustin A. Tracy , N. A. Viet

We detect 39 nm x 10 nm gold nanorods using a microtoroid stabilized via the Pound-Drever-Hall method. Real-time detection is achieved with signal-to-noise ratios up to 12.2. These nanoparticles are a factor of three smaller in volume than…

Optics · Physics 2015-06-15 Jon D. Swaim , Joachim Knittel , Warwick P. Bowen

The interaction of DNA nucleobases with monolayer GaSe has been studied with in DFT framework using vdW functional. We found that nucleobases are physisorbed on the GaSe monolayer. The order of binding energy per atom is C > T > G > A. The…

Mesoscale and Nanoscale Physics · Physics 2021-02-10 Kuldeep Kumar , Munish Sharma

In the current era, DeoxyriboNucleic Acid (DNA) based data storage emerges as an intriguing approach, garnering substantial academic interest and investigation. This paper introduces a novel deep joint source-channel coding (DJSCC) scheme…

Emerging Technologies · Computer Science 2023-11-03 Wenfeng Wu , Luping Xiang , Qiang Liu , Kun Yang