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Studies of biological solutions require high measurement accuracy, the ability to detect low changes in substance concentration, and small amounts of the liquid under test. A microwave complex permittivity measurement technique based on a…

Optical mapping by direct visualization of individual DNA molecules, stretched in nanochannels with sequence-specific fluorescent labeling, represents a promising tool for disease diagnostics and genomics. An important challenge for this…

Quantitative Methods · Quantitative Biology 2015-01-21 Charleston Noble , Adam N. Nilsson , Camilla Freitag , Jason P. Beech , Jonas O. Tegenfeldt , Tobias Ambjörnsson

Whispering gallery mode (WGM) of resonance occurs when a traveling wave faces grazing reflection and confinement at the inner surface of a spherical cavity. Such a resonance was observed with micrometer sized liquid droplet and with light…

Optics · Physics 2024-04-29 S. M. Iftiquar

Optical microcavity enhanced light-matter interaction offers a powerful tool to develop fast and precise sensing techniques, spurring applications in the detection of biochemical targets ranging from cells, nanoparticles, and large…

The recent progress in DNA sequencing will probably revolutionize the world of electronic. Hence, we went from DNA sequencing that only research centers could realize, to portable, tiny and inexpensive tools. So, it is likely that in a few…

Cryptography and Security · Computer Science 2016-06-22 Amadou Moctar Kane

A general theoretical framework is put forth to organize and understand various observed phenomena and mathematical relationships in the field of molecular biology. By modeling each cell in eukaryotic organisms as a processor having a…

Other Quantitative Biology · Quantitative Biology 2013-12-18 Barry D. Jacobson

This work demonstrates the Nd:YAG waveguide laser as an efficient platform for the bio-sensing. The waveguide was fabricated in the Nd:YAG crystal by the cooperation of the ultrafast laser writing and ion irradiation. As the laser…

Many industrial soft materials often include oil-in-water (O/W) emulsions at the core of their formulations. By using tuneable interface stabilizing agents, such emulsions can self-assemble into complex structures. DNA has been used for…

With ever increasing research on magnetic nano systems it is shown to have great potential in the areas of magnetic storage, biosensing, magnetoresistive insulation etc. In the field of biosensing specifically Spin Valve sensors coupled…

Emerging Technologies · Computer Science 2015-12-01 Tathagata Srimani , Bibhas Manna , Anand Kumar Mukhopadhyay , Kaushik Roy , Mrigank Sharad

Fluorescent nanodiamonds (fNDs) containing Nitrogen Vacancy (NV) centres are promising candidates for quantum sensing in biological environments. However, to date, there has been little progress made to combine the sensing capabilities of…

Applied Physics · Physics 2018-12-06 J. C. Price , S. J. Levett , V. Radu , D. A. Simpson , A. Mogas Barcons , C. F. Adams , M. L. Mather

A purely electrical sensing scheme is presented that determines the concentration of macromolecules in solution by measuring the capacitance between planar microelectrodes. Concentrations of DNA in the ng/mL range have been used in samples…

Biological Physics · Physics 2009-01-20 Anja Henning , Joerg Henkel , Frank F Bier , Ralph Hoelzel

The folding of RNA and DNA strands plays crucial roles in biological systems and bionanotechnology. However, studying these processes with high-resolution numerical models is beyond current computational capabilities due to the timescales…

Soft Condensed Matter · Physics 2024-02-07 F. Tosti Guerra , E. Poppleton , P. Šulc , L. Rovigatti

Whispering gallery mode (WGM) microcavities can confine photons within a microscale volume for long periods of time, strongly enhancing light-matter interactions, and making it a crucial platform in optical science and applications. Current…

Applied Physics · Physics 2023-04-07 Fangxing Zhang , Shengnan HuangFu , Jialve Sun , Shengqiang Ji , Yanjie Bai , Yunfeng Xiao

MicroRNAs (miRNAs) are an emerging class of biomarkers that are frequently deregulated in cancer cells and have shown a great promise for cancer classification and prognosis. In this work, we developed a three-way electrochemical sensor for…

Biomolecules · Quantitative Biology 2013-12-02 Mahmoud Labib , Nasrin Khan , Jenny Cheng , John Paul Pezacki , Maxim V. Berezovski

Subject to intricate environmental variables, the precise classification of jamming signals holds paramount significance in the effective implementation of anti-jamming strategies within communication systems. In light of this imperative,…

Signal Processing · Electrical Eng. & Systems 2024-06-27 Xuhui Ding , Yue Zhang , Gaoyang Li , Xiaozheng Gao , Neng Ye , Dusit Niyato , Kai Yang

Purpose Nanopore-based molecular sensing and measurement, specifically Deoxyribonucleic acid (DNA) sequencing, is advancing at a fast pace. Some embodiments have matured from coarse particle counters to enabling full human genome assembly.…

Instrumentation and Detectors · Physics 2021-10-06 Mehdi Habibi , Yunus Dawji , Ebrahim Ghafar-Zadeh , Sebastian Magierowski

DNA melting and hybridization is a fundamental biological process as well as a crucial step in many modern biotechnology applications. DNA confined on surfaces exhibits different behavior from that in free solutions. The system of…

Biological Physics · Physics 2007-05-23 Y. Sun , N. C. Harris , C. -H. Kiang

DNA computing, a nontraditional computing mechanism, provides a feasible and effective method for solving NP-hard problems because of the vast parallelism and high-density storage of DNA molecules. Although DNA computing has been exploited…

Molecular Networks · Quantitative Biology 2022-11-17 Enqiang Zhu , Xianhang Luo , Chanjuan Liu , Xiaolong Shi , Jin Xu

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

Gel electrophoresis, a widely used technique to separate DNA according to their size and weight, generates images that can be analyzed automatically. Manual or semiautomatic image processing presents a bottleneck for further development and…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Naima Kaabouch , Richard R. Schultz , Barry Milavetz , Lata Balakrishnan