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Shear-wave Elastography Imaging (SWEI) is a noninvasive imaging modality that provides tissue elasticity information by measuring the travelling speed of an induced shear-wave. It is commercially available on clinical ultrasound scanners…

Medical Physics · Physics 2022-04-21 Bhaskara Rao Chintada , Richard Rau , Orcun Goksel

As an effective method to deliver external materials into biological cells, microinjection has been widely applied in the biomedical field. However, the cognition of cell mechanical property is still inadequate, which greatly limits the…

Robotics · Computer Science 2022-11-29 Shengzheng Kang , Zhicheng Song , Xiaolong Yang , Yao Li , Hongtao Wu , Tao Li

Elastic confinements are an important component of many biological systems and dictate the transport properties of suspended particles under flow. In this chapter, we review the Brownian motion of a particle moving in the vicinity of a…

Soft Condensed Matter · Physics 2022-10-28 Abdallah Daddi-Moussa-Ider , Stephan Gekle

The purpose of this study was to develop a method for tissue elasticity imaging using tagged magnetic resonance imaging (MRI). First, we developed a cyclic pressure device that used air to remotely transmit the power to generate cyclic…

Medical Physics · Physics 2020-02-07 Tomoki Takeuchi , Ryosuke Nasada , Kenya Murase

Biomembranes consisting of two opposing phospholipid monolayers, which comprise the so-called lipid bilayer, are largely responsible for the dual solid-fluid behavior of individual cells and viruses. Quantifying the mechanical…

Biological Physics · Physics 2024-05-27 Naoki Takeishi , Masaya Santo , Naoto Yokoyama , Shigeo Wada

A variant of compression optical coherence elastography for mapping relative tissue stiffness is reported. Unlike conventionally discussed displacement-based (DB) elastorgaphy, in which the decrease in the cross-correlation is a negative…

Displacement estimation in optical coherence tomography (OCT) imaging is relevant for several potential applications, e.g. for optical coherence elastography (OCE) for corneal biomechanical characterization. Larger displacements may be…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Hossein Khodadadi , Orcun Goksel , Sabine Kling

The determination of crystallographic texture through elastic wave propagation offers a cost-effective, nondestructive means of obtaining through-thickness information with minimal sample preparation. Existing ultrasonic approaches rely on…

Materials Science · Physics 2026-05-19 Diego A. Cowes , Juan I. Mieza , Martín P. Gómez

We present a contactless method for measuring the elastic modulus of living cells (human triple-negative breast cancer, MDA-MB-231) from the thermal fluctuations of an atomic force microscope (AFM) cantilever. By analyzing the power…

Soft Condensed Matter · Physics 2025-05-01 Hao Zhang , Zaicheng Zhang , Etienne Harte , Francoise Argoul , Abdelhamid Maali

In high intensity focused ultrasound (HIFU) systems using non-ionizing methods in cancer treatment, if the device is applied to the body externally, the HIFU beam can damage nearby healthy tissues and burn skin due to lack of knowledge…

Purpose. To demonstrate accurate measurement of corneal elastic moduli in vivo with non-contact and non-invasive optical coherence elastography. Methods. Elastic properties (in-plane Young's modulus E and both in-plane, u, and out-of-plane,…

A number of questions in systems biology such as understanding how dynamics of neuronal networks are related to brain function require the ability to capture the functional dynamics of large cellular populations at high speed. Recently,…

Mechanical stress within biological tissue can indicate an anomaly, or can be vital of its function, such as stresses in arteries. Measuring these stresses in tissue is challenging due to the complex, and often unknown, nature of the…

Soft Condensed Matter · Physics 2024-02-27 Harold Berjamin , Artur L. Gower

Mechanical cues from the extracellular microenvironment play a central role in regulating the structure, function and fate of living cells. Nevertheless, the precise nature of the mechanisms and processes underlying this crucial cellular…

Biological Physics · Physics 2015-06-23 Ariel Livne , Eran Bouchbinder , Benjamin Geiger

Viscosity is a key property of cell membranes that controls mobility of embedded proteins and membrane remodeling. Measuring it is challenging because existing approaches involve complex experimental designs and/or models, and the…

Soft Condensed Matter · Physics 2023-07-19 Hammad A. Faizi , Rumiana Dimova , Petia M. Vlahovska

We report a systematic study to determine local elastic properties of surfaces combining atomic force microscope (AFM) with acoustic waves which is known as atomic force acoustic microscopy - AFAM. We describe the methodology of AFAM in…

Materials Science · Physics 2007-05-23 S. Banerjee , N. Gayathri , S. R. Shannigrahi , S. Dash , A. K. Tyagi , B. Raj

We present Monte Carlo simulations of an ultra coarse-grained lipid bilayer with different number of lipids on both leaflets. In the simulations, we employ a new method for measuring the elastic parameters of the membrane, including the…

Soft Condensed Matter · Physics 2025-05-20 Oded Farago

Many wormlike micellar systems exhibit appreciable shear thinning due to shear induced alignment. As the micelles get aligned introducing directionality in the system, the viscoelastic properties are no longer expected to be isotropic. An…

Soft Condensed Matter · Physics 2011-05-09 Manas Khan , A. K. Sood

In the emerging field of 3D bioprinting, cell damage due to large deformations is considered a main cause for cell death and loss of functionality inside the printed construct. Those deformations, in turn, strongly depend on the…

The shear-induced deformation of a capsule with a stiff nucleus, a model of eukaryotic cells, is studied numerically. The membrane of the cell and of its nucleus are modelled as a thin and impermeable elastic material obeying a Neo-Hookean…

Fluid Dynamics · Physics 2017-05-29 Arash Alizad Banaei , Jean-Christophe Loiseau , Iman Lashgari , Luca Brandt
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