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Cell membrane tension directly influences various cellular functions. In this study, we developed a method to estimate surface tension from time-series data. We obtained the curvature-velocity relationship from time-series of binarized cell…

Cell Behavior · Quantitative Biology 2025-04-22 Hiroki Nishitani , Takashi Miura

Atomistic deformation simulations in the nominally elastic regime are performed for a model binary glass with strain rates as low as $10^{4}$/sec (corresponding to 0.01 shear strain per 1$\mu$sec). A robust elasticity is revealed that…

Soft Condensed Matter · Physics 2020-11-21 P. M. Derlet , R. Maass

Brillouin imaging is an emerging optical elastography technique able to generate maps of the mechanical properties at microscale, with great potential in biophysical and biomedical fields. A key parameter is its spatial resolution, which is…

Optics · Physics 2020-02-28 Silvia Caponi , Daniele Fioretto , Maurizio Mattarelli

This study presents the first observation of shear wave induced remotely within soft tissues. It was performed through the combination of a transcranial magnetic stimulation device and a permanent magnet. A physical model based on Maxwell…

Medical Physics · Physics 2016-05-11 Pol Grasland-Mongrain , Erika Miller-Jolicoeur , An Tang , Stefan Catheline , Guy Cloutier

Biological cells in soft materials can be modeled as anisotropic force contraction dipoles. The corresponding elastic interaction potentials are long-ranged ($\sim 1/r^3$ with distance $r$) and depend sensitively on elastic constants,…

Soft Condensed Matter · Physics 2009-11-07 U. S. Schwarz , S. A. Safran

We show that the atomic force microscope can perform stress relaxation and creep compliance measurements on living cells. We propose a method to obtain the mechanical properties of the studied biomaterial: the relaxation time, the elastic…

Biological Physics · Physics 2015-05-18 Susana Moreno-Flores , Rafael Benitez , Maria dM Vivanco , Jose Luis Toca-Herrera

Structural microvascular alterations and dysfunction serve as key disease indicators of cancer, diabetes, ischemic stroke, neurodegenerative disorders and many other conditions. In vivo visualization of the microvasculature has…

Biological Physics · Physics 2020-07-02 Xosé Luís Deán-Ben , Justine Robin , Ruiqing Ni , Daniel Razansky

The biomechanical properties of cells and tissues play an important role in our fundamental understanding of the structures and functions of biological systems at both the cellular and subcellular levels. Recently, Brillouin microscopy,…

Electromotility of outer hair cells (OHCs) has been extensively studied with in vitro experiments because of its physiological significance in the cochlear amplifier, which provides the exquisite sensitivity and frequency selectivity of the…

Biological Physics · Physics 2016-12-08 Kuni H Iwasa

As disease often alters the structural properties of soft tissue, noninvasive elastography techniques have emerged to quantitatively assess in vivo mechanical properties. Magnetic Resonance Elastography (MRE) based on dynamic deformations…

Mechanical strain and stress play a major role in biological processes such as wound healing or morphogenesis. To assess this role quantitatively, fixed or live images of tissues are acquired at a cellular precision in large fields of…

Tissues and Organs · Quantitative Biology 2019-06-12 M. Durande , S. Tlili , T. Homan , B. Guirao , F. Graner , H. Delanoë-Ayari

The distinction between malignant and benign tumors is essential to the treatment of cancer. The tissue's elasticity can be used as an indicator for the required tissue characterization. Optical coherence elastography (OCE) probes have been…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Robin Mieling , Johanna Sprenger , Sarah Latus , Lennart Bargsten , Alexander Schlaefer

Patch-clamp technique is the gold standard for cellular electrophysiological measurements, which is capable of measuring single ion transport events across the cell membrane. However, the measurement possesses significant complexity, and it…

Instrumentation and Detectors · Physics 2021-01-21 Ali Aytac Seymen , Erol Ozgur , Zeliha Soran-Erdem , Bulend Ortac

Breast implants are widely used after breast cancer resection and must be changed regularly to avoid a rupture. To date, there are no quantitative criteria to help this decision. The mechanical evolution of the gels and membranes of the…

The measurement of cellular traction forces on soft elastic substrates has become a standard tool for many labs working on mechanobiology. Here we review the basic principles and different variants of this approach. In general, the…

Quantitative Methods · Quantitative Biology 2015-06-09 Ulrich S. Schwarz , Jerome R. D. Soine

This paper introduces a micro-lattice based metamaterial for low frequency wide-band vibration attenuation, that is enabled by engineering the metamaterial's building blocks to induce local resonance bandgaps for elastic waves in all…

Applied Physics · Physics 2019-12-19 Nikhil JRK Gerard , Mourad Oudich , Yun Jing

High throughput real-time instruments are needed to acquire large data sets for detection and classification of rare events. Enabled by the photonic time stretch digitizer, a new class of instruments with record throughputs have led to the…

Optics · Physics 2015-03-20 Bahram Jalali , Ata Mahjoubfar , Claire L. Chen

We develop and thoroughly test a stress-controlled, parallel plates shear cell that can be coupled to an optical microscope or a small angle light scattering setup, for simultaneous investigation of the rheological properties and the…

Soft Condensed Matter · Physics 2017-01-04 S. Aime , L. Ramos , J. -M. Fromental , G. Prévot , R. Jelinek , L. Cipelletti

The soft character of organic materials leads to strong coupling between molecular nuclear and electronic dynamics. This coupling opens the way to control charge transport in organic electronic devices by inducing molecular vibrational…

A body force concentrated at a point and moving at a high speed can induce shear-wave Mach cones in dusty-plasma crystals or soft materials, as observed experimentally and named the elastic Cherenkov effect (ECE). The ECE in soft materials…

Soft Condensed Matter · Physics 2020-09-03 Guo-Yang Li , Yang Zheng , Yanlin Liu , Michel Destrade , Yanping Cao