Related papers: Ultrafast imaging of cell elasticity with optical …
Thin elastic sheets and membranes are known to wrinkle when they are stretched -- the associated physics is highly non-linear. The mechanics of thin films that exhibit unusual behavior upon stretching, when they possess auxetic structure,…
Atomic Force Microscopy (AFM) has a great potential as a tool to characterize mechanical and morphological properties of living cells; these properties have been shown to correlate with cells' fate and patho-physiological state in view of…
The flow behavior of a viscoelastic organogel is investigated using ultrasonic velocimetry combined with rheometry. Our gel presents a decreasing flow curve, i.e., the measured stress decreases as a function of the applied shear rate.…
Spherical cellular aggregates are in vitro systems to study the physical and biophysical properties of tissues. We present a novel approach to characterize the mechanical properties of cellular aggregates using micropipette aspiration…
Here we report on the viscosity of eukaryotic living cells as a function of the time, and on the application of stochastic models to analyze its temporal fluctuations. The viscoelastic properties of NIH/3T3 fibroblastic cells are…
Mass density is a vital property for improved biophysical understanding of and within biological samples. It is increasingly attracting active investigation, but still lacks reliable, non-contact techniques to accurately characterize it in…
Measurements with an atomic force microscope (AFM) offer a direct way to probe elastic properties of lipid bilayer membranes locally: provided the underlying stress-strain relation is known, material parameters such as surface tension or…
Objectives: Magnetic resonance elastography (MRE) is a noninvasive technique for assessing the viscoelastic properties of soft biological tissues in vivo, with potential relevance for pediatric tumor evaluation. This study aimed to evaluate…
Two dimensional simulations of non-cohesive granular matter in a biaxial shear tester are discussed. The effect of particle elasticity on the mechanical behavior is investigated using two complementary distinct element methods (DEM): Soft…
Elastic wave propagation is intrinsically sensitive to the mechanical properties of the medium through which it travels. In soft elastomers, this makes guided elastic waves natural probes of viscoelastic and acoustoelastic behavior over a…
A curious feature of organ and organoid morphogenesis is that in certain cases, spatial oscillations in the thickness of the growing "film" are out-of-phase with the deformation of the slower-growing "substrate," while in other cases, the…
Wave propagation on the surface of a material contains information about physical properties beneath its surface. We propose a method for inferring the thickness and stiffness of a structure from just a video of waves on its surface. Our…
Normal thermal fluctuations of the cell membrane have been studied extensively using high resolution microscopy and focused light, particularly at the peripheral regions of a cell. We use a single probe particle attached non-specifically to…
Numerical investigation of the interaction of electromagnetic fields with eukaryotic cells requires specifically adapted computer models. Virtual microdosimetry, used to investigate exposure, requires volumetric cell models, which are…
Subwavelength imaging of elastic/acoustic waves using phononic crystals (PCs) is limited to a narrow frequency range via the two existing mechanisms that utilize either the intense Bragg scattering in the first phonon band or negative…
Understanding mechanosensitivity, i.e. how cells sense the stiffness of their environment is very important, yet there is a fundamental difficulty in understanding its mechanism: to measure an elastic modulus one requires two points of…
We propose an approach to measure surface elastic constants of soft solids. Generally, this requires one to probe interfacial mechanics at around the elastocapillary length scale, which is typically microscopic. Deformations of microscopic…
In this work, two-dimensional simulations of the microwave dielectric properties of models with ellipses and realistic models of trabecular bone tissue are performed. In these simulations, finite difference time domain methodology has been…
Recent studies have highlighted intracellular viscosity as a key biomechanical property with potential as a biomarker for cancer cell metastasis. In the context of cellular mechanobiology, magnetic rotational spectroscopy (MRS), which…
Serial section electron microscopy (ssEM) is a widely used technique for obtaining volumetric information of biological tissues at nanometer scale. However, accurate 3D reconstructions of identified cellular structures and volumetric…