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The appearance of nonlinear effects in elastic wave propagation is one of the most reliable and sensitive indicators of the onset of material damage. However, these effects are usually very small and can be detected only using cumbersome…

The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals received from their environment, is crucial for the functioning of all biological systems. In experiments, cells placed on cyclically…

Biological Physics · Physics 2019-01-17 John J. Molina , Ryoichi Yamamoto

The heterogeneous micromechanical properties of biological tissues have profound implications across diverse medical and engineering domains. However, identifying full-field heterogeneous elastic properties of soft materials using…

Numerical Analysis · Mathematics 2025-07-09 Wensi Wu , Mitchell Daneker , Kevin T. Turner , Matthew A. Jolley , Lu Lu

The mechanical properties of biological tissues are strongly correlated to the specific distribution of their collagen fibers. Monitoring the dynamic reorganization of the collagen network during mechanical stretching is however a technical…

The possible disruption of a microtubule during mitosis can control the duplication of a cancer cell. Cancer detection and treatment may be possible based on the detection and control of microtubule mechanical oscillations in cells through…

Quantum Physics · Physics 2017-07-19 Sh. Barzanjeh , V. Salari , J. A. Tuszynski , M. Cifra , C. Simon

Non-invasive vascular elastography is an emerging technique in vascular tissue imaging. During the past decades, several techniques have been suggested to estimate the tissue elasticity by measuring the displacement of the Carotid vessel…

Brillouin scattering in optical fibres is a fundamental interaction between light and sound with important implications ranging from optical sensors to slow and fast light. In usual optical fibres, light both excites and feels shear and…

In tissue development, wound healing, and cancer invasion, coordinated cell motion arises from active forces produced by the cells. The relationship between force and motion remains unclear, however, because the forces result from a sum of…

Biological Physics · Physics 2025-12-17 Molly McCord , Jacob Notbohm

Soft tissue elasticity is directly related to different stages of diseases and can be used for tissue identification during minimally invasive procedures. By palpating a tissue with a robot in a minimally invasive fashion force-displacement…

State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant…

Soft Condensed Matter · Physics 2012-05-04 Gal deBotton , Tal Oren

We use a custom shear cell coupled to an optical microscope to investigate at the particle level the yielding transition in concentrated emulsions subjected to an oscillatory shear deformation. By performing experiments lasting thousands of…

Soft Condensed Matter · Physics 2014-08-27 E. D. Knowlton , D. J. Pine , L. Cipelletti

Purpose: To evaluate changes in the anisotropic elastic properties of ex vivo human cornea treated with UV cross-linking (CXL) using non-contact acoustic micro-tapping Optical Coherence Elastography (AuT-OCE) Design: AuT performed on normal…

We describe a high-resolution, high-bandwidth technique for determining the local viscoelasticity of soft materials such as polymer gels. Loss and storage shear moduli are determined from the power spectra of thermal fluctuations of…

Soft Condensed Matter · Physics 2009-10-30 F. Gittes , B. Schnurr , P. D. Olmsted , F. C. MacKintosh , C. F. Schmidt

A Molecular Dynamics approach has been used to compute the shear force resulting from the shearing of disks. Two-dimensional monodisperse disks have been put in an horizontal and rectangular shearing cell with periodic boundary conditions…

Soft Condensed Matter · Physics 2008-09-29 O. Pozo , N. Olivi-Tran

The elasticity of soft tissues has been widely considered as a characteristic property to differentiate between healthy and vicious tissues and, therefore, motivated several elasticity imaging modalities, such as Ultrasound Elastography,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-30 Weiguo Cao , Marc J. Pomeroy , Zhengrong Liang , Yongfeng Gao , Yongyi Shi , Jiaxing Tan , Fangfang Han , Jing Wang , Jianhua Ma , Hongbin Lu , Almas F. Abbasi , Perry J. Pickhardt

Living tissues experience various external forces on cells, influencing their behaviour, physiology, shape, gene expression, and destiny through interactions with their environment. Despite much research done in this area, challenges remain…

Quantitative Methods · Quantitative Biology 2024-03-05 Akepogu Venkateshwarlu , Akshayveer , Sundeep Singh , Roderick Melnik

Mechanical and elastic properties of materials are among the most fundamental quantities for many engineering and industrial applications. Here, we present a formulation that is efficient and accurate for calculating the elastic and bending…

Materials Science · Physics 2026-03-23 Changpeng Lin , Samuel Poncé , Francesco Macheda , Francesco Mauri , Nicola Marzari

Mechanical properties of the cell are important biomarkers for probing its architectural changes caused by cellular processes and/or pathologies. The development of microfluidic technologies have enabled measuring cell mechanics at…

Soft Condensed Matter · Physics 2021-05-19 Moslem Moradi , Ehssan Nazockdast

We derive closed-form solutions for reverberant elastography in anisotropic elastic media by adapting the framework used in electromagnetic theory to treat transverse isotropic materials. Different sample-setup geometries are analyzed,…

Medical Physics · Physics 2020-11-12 Luis A. Aleman-Castaneda , Fernando Zvietcovich , Kevin J. Parker

Lipid membranes are abundant in living organisms, where they constitute a surrounding shell for cells and their organelles. There are many circumstances in which the deformations of lipid membranes are involved in living cells: fusion and…

Soft Condensed Matter · Physics 2022-11-17 Konstantin V. Pinigin