English

Correlation-stability approach to elasticity mapping in OCT: comparison with displacement-based mapping and \textit{in vivo} demonstrations

Medical Physics 2014-11-04 v1 Biological Physics Quantitative Methods

Abstract

A variant of compression optical coherence elastography for mapping relative tissue stiffness is reported. Unlike conventionally discussed displacement-based (DB) elastorgaphy, in which the decrease in the cross-correlation is a negative factor causing errors in mapping displacement and strain fields, we propose to intentionally use the difference in the correlation stability (CS) for deformed tissue regions with different stiffness. We compare the parameter ranges (in terms of noise-to-signal ratio and strain) in which the conventional DB- and CS-approaches are operable. It is shown that the CS approach has such advantages as significantly wider operability region in terms of strain and is more tolerant to noises. This is favorable for freehand implementation of this approach. Examples of simulated and real CS-based elastographic OCT images are given.

Keywords

Cite

@article{arxiv.1212.5227,
  title  = {Correlation-stability approach to elasticity mapping in OCT: comparison with displacement-based mapping and \textit{in vivo} demonstrations},
  author = {Vladimir Yu. Zaitsev and Lev A. Matveev and Grigory V. Gelikonov and Aleksandr L. Matveyev and Valentin M. Gelikonov},
  journal= {arXiv preprint arXiv:1212.5227},
  year   = {2014}
}

Comments

4 pages, including 3 pages of the body text and 1 page with full-form references, 3 figures