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The effect of AC electric fields on the elasticity of supported lipid bilayers has been investigated at the microscopic level using grazing incidence synchrotron x-ray scattering. A strong decrease in the membrane tension up to 1mN/m and a…

Soft Condensed Matter · Physics 2016-06-08 Arnaud Hemmerle , Thierry Charitat , Giovanna Fragneto , Jean Daillant

Optical coherence elastography allows the characterization of the mechanical properties of tissues, and can be performed through estimating local displacement maps from subsequent acquisitions of a sample under different loads. This…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Jonathan H. Mason , Yvonne Reinwald , Ying Yang , Sarah Waters , Alicia El Haj , Pierre O. Bagnaninchi

Objective: Ultrasound elastography is gaining traction as an accessible and useful diagnostic tool for such things as cancer detection and differentiation and thyroid disease diagnostics. Unfortunately, state of the art shear wave imaging…

Machine Learning · Computer Science 2019-07-31 Micha Feigin , Daniel Freedman , Brian W. Anthony

We present a novel approach to probe elastic properties of polyelectrolyte multilayer microcapsules. The method is based on measurements of the capsule load-deformation curves with the atomic force microscope. The experiment suggests that…

Soft Condensed Matter · Physics 2009-11-10 V. V. Lulevich , D. Andrienko , O. I. Vinogradova

Dynamic optical coherence elastography (OCE) tracks mechanical wave propagation in the subsurface region of tissue to image its shear modulus. For bulk shear waves, the lateral resolution of the reconstructed modulus map (i.e.,…

Recent advances recognize that the viscoelastic properties of epithelial structures play important roles in biology and disease modeling. However, accessing the viscoelastic properties of multicellular structures in mechanistic or…

Soft Condensed Matter · Physics 2023-04-21 Tianzheng Guo , Xiaoyu Zou , Shalini Sundar , Xinqiao Jia , Charles Dhong

Brillouin microscopy is an emerging optical elastography technique that can be used to assess mechanical properties of biological samples in a 3D, all-optical and hence non-contact fashion. However, the low cross-section of spontaneous…

Optics · Physics 2024-09-04 Carlo Bevilacqua , Robert Prevedel

We measure different contributions to entropy production in a living functional epithelial tissue. We do this by extracting the functional dynamics of development while at the same time quantifying fluctuations. Using the translucent…

Soft Condensed Matter · Physics 2023-01-25 Mark Olenik , Jake Turley , Stephen Cross , Helen Weavers , Paul Martin , Isaac Chenchiah , Tanniemola Liverpool

Brillouin light scattering spectroscopy was used along with detailed composition information obtained from electron probe microanalysis to study the influence of octahedral site chemistry on the elastic properties of biotite crystals.…

Materials Science · Physics 2023-02-22 Dillon F. Hanlon , G. Todd Andrews , Roger A. Mason

Biological cells are built up from many different constituents of varying size and stiffness which all contribute to the cell's mechanical properties. Despite this heterogeneity, in the analysis of experimental measurements such as atomic…

Biological Physics · Physics 2023-05-18 Sebastian Wohlrab , Sebastian J. Müller , Stephan Gekle

Image acquisition techniques such as micro-computed tomography are nowadays widely available. Quantitative analysis of the resulting 3D image data enables geometric characterization of the micro-structure of materials. Stochastic geometry…

Numerical Analysis · Mathematics 2025-01-28 Anne Jung , Claudia Redenbach , Katja Schladitz , Sarah Staub

Impedance Spectroscopy resolves electrical properties into uncorrelated variables, as a function of frequency, with exquisite resolution. Separation is robust and most useful when the system is linear. Impedance spectroscopy combined with…

Quantitative Methods · Quantitative Biology 2015-11-05 Robert Eisenberg

Thanks to its capability of acquiring full-view frames at multiple kilohertz, ultrafast ultrasound imaging unlocked the analysis of rapidly changing physical phenomena in the human body, with pioneering applications such as ultrasensitive…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Dimitris Perdios , Manuel Vonlanthen , Florian Martinez , Marcel Arditi , Jean-Philippe Thiran

We report on a laser generated and detected surface acoustic wave method for evaluating the elastic constants of micro-crystals composing polycrystalline steel. The method is based on the measurement of surface wave velocities in many…

Elastographic imaging is a widely used technique which can in principle be implemented on top of every imaging modality. In elastography, the specimen is exposed to a force causing local displacements in the probe, and imaging is performed…

Optimization and Control · Mathematics 2014-07-28 Thomas Glatz , Otmar Scherzer , Thomas Widlak

We have developed a new technique to measure viscoelasticity in soft materials such as polymer solutions, by monitoring thermal fluctuations of embedded probe particles using laser interferometry in a microscope. Interferometry allows us to…

Soft Condensed Matter · Physics 2009-10-30 B. Schnurr , F. Gittes , F. C. MacKintosh , C. F. Schmidt

Shear-wave elastography (SWE) measures shear-wave speed (SWS), which is related to the underlying shear modulus of soft tissue. SWE methods generally assume that soft tissue viscoelasticity is independent of mechanical loading, however,…

Medical Physics · Physics 2022-04-21 Bhaskara R. Chintada , Richard Rau , Orcun Goksel

In biological tissue, an increase in elasticity is often a marker of abnormalities. Techniques such as quasi-static ultrasound elastography have been developed to assess the strain distribution in soft tissues in two dimensions using a…

Medical Physics · Physics 2023-04-12 Clement Papadacci , Ethan A Bunting , Elisa E Konofagou

Brillouin light scattering spectroscopy (BLS) is applied to study the micromechanics of cellulosic viscose fibers, one of the commercially most important, man-made biobased fibers. Using an equal angle scattering geometry, we provide a…

Mechanical characteristics of single biological cells are used to identify and possibly leverage interesting differences among cells or cell populations. Fluidity---hysteresivity normalized to the extremes of an elastic solid or a viscous…

Cell Behavior · Quantitative Biology 2013-10-22 John M. Maloney , Eric Lehnhardt , Alexandra F. Long , Krystyn J. Van Vliet