Related papers: Ultrafast imaging of cell elasticity with optical …
Accurate assessment of stiffness distribution is essential due to the critical role of single cell mechanobiology in the regulation of many vital cellular processes such as proliferation, adhesion, migration, and motility. Cell stiffness is…
We introduce a model-based iterative method to obtain shear modulus images of tissue using magnetic resonance elastography. The method jointly finds the displacement field that best fits multifrequency tissue displacement data and the…
In vivo measurement of the mechanical properties of thin-walled soft tissues (e.g., mitral valve, artery and bladder) and in situ mechanical characterization of thin-walled artificial soft biomaterials in service are of great challenge and…
3D ultrasound imaging provides more spatial information compared to conventional 2D frames by considering the volumes of data. One of the main bottlenecks of 3D imaging is the long data acquisition time which reduces practicality and can…
Skeletal muscles are organized into distinct layers and exhibit anisotropic characteristics across various scales. Assessing the arrangement of skeletal muscles may provide valuable biomarkers for diagnosing muscle related pathologies and…
In this study, Brillouin spectroscopy was employed to investigate the viscoelastic properties of melanoma cells in vitro. Using a custom-built confocal Brillouin microspectrometer, we obtained Brillouin shifts and full width at half maximum…
There are many fields where it is of interest to measure the elastic moduli of tiny fragile fibers, such as filamentous bacteria, actin filaments, DNA, carbon nanotubes, and functional microfibers. The elastic modulus is typically deduced…
Estimating the elasticity of soft tissue can provide useful information for various diagnostic applications. Ultrasound shear wave elastography offers a non-invasive approach. However, its generalizability and standardization across…
We studied the elastic properties of bone to analyze its mechanical behavior. The basic principles of ultrasonic methods are now well established for varying isotropic media, particularly in the field of biomedical engineering. However,…
Many problems in mechanobiology urgently require characterisation of the micromechanical properties of the fibrous proteins of cells and tissues. Brillouin light scattering has been proposed as a new optical elastography technique to meet…
Model-based computational elasticity imaging of tissues can be posed as solving an inverse problem over finite elements spanning the displacement image. As most existing quasi-static elastography methods count on deterministic formulations…
Arterial biomechanical indicators have long been recognized as fundamental contributors to the physiology and pathology of cardiovascular systems. Probing the multiple biomechanical parameters of arteries simultaneously at different time…
Recent advances in optical technology have significantly enhanced the resolution of imaging of living cells, achieving nanometer-scale precision. However, the crowded three-dimensional environment within cells presents a challenge for…
Biological cells sense and respond to mechanical forces, but how such a mechanosensing proccess takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show that cells in a fibrous matrix induce deformation fields that…
Photoacoustic imaging and sensing have been studied extensively to probe the optical absorption of biological tissue in multiple scales ranging from large organs to small molecules. However, its elastic oscillation characterization is…
Viscosity is an important property of out-of-equilibrium systems such as active biological materials and driven non-Newtonian fluids, and for fields ranging from biomaterials to geology, energy technologies and medicine. However,…
We present an experimental protocol for the fabrication and characterization of scalable microarchitected elastic waveguides. Using silicon microfabrication techniques, we develop free-standing 2D truss-based architected waveguides with a…
We describe a technique coupling standard rheology and ultrasonic imaging with promising applications to characterization of soft materials under shear. Plane wave imaging using an ultrafast scanner allows to follow the local dynamics of…
We use supersonic shear wave imaging (SSI) technique to measure not only the linear but also the nonlinear elastic properties of brain matter. Here, we tested six porcine brains ex vivo and measured the velocities of the plane shear waves…
Vibrational spectroscopy is a ubiquitous technology that derives the species, constituents, and morphology of an object from its natural vibrations. However, the vibrational spectra of mesoscopic particles - including most biological cells…