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Phase-field models are a popular choice in computational physics to describe complex dynamics of substances with multiple phases and are widely used in various applications. We present nonlocal non-isothermal phase-field models of…

Analysis of PDEs · Mathematics 2023-10-13 Olena Burkovska

In this work, we present a phase-field model for tumour growth, where a diffuse interface separates a tumour from the surrounding host tissue. In our model, we consider transport processes by an internal, non-solenoidal velocity field. We…

Numerical Analysis · Mathematics 2024-06-21 Harald Garcke , Dennis Trautwein

In this paper, we address an optimal distributed control problem for a non-local model of phase-field type, describing the evolution of tumour cells in presence of a nutrient. The model couples a non-local and viscous Cahn-Hilliard equation…

Analysis of PDEs · Mathematics 2023-10-25 Matteo Fornoni

This paper deals with a nonlocal model for a hyperbolic phase field system coupling the standard energy balance equation for temperature with a dynamic for the phase variable: the latter includes an inertial term and a nonlocal…

Analysis of PDEs · Mathematics 2024-02-20 Pierluigi Colli , Shunsuke Kurima , Luca Scarpa

New types of stationary solutions of a one-dimensional driven sixth-order Cahn-Hilliard type equation that arises as a model for epitaxially growing nano-structures such as quantum dots, are derived by an extension of the method of matched…

Mathematical Physics · Physics 2008-11-14 M. D. Korzec , P. L. Evans , A. Münch , B. Wagner

Cancer is a very complex phenomenon that involves many different scales and situations. In this paper we consider a free boundary problem describing the evolution of a tumor colony and we derive a new asymptotic model for tumor growth. We…

Analysis of PDEs · Mathematics 2025-04-15 Rafael Granero-Belinchón , Martina Magliocca

A system with equation and dynamic boundary condition of Cahn-Hilliard type is considered. This system comes from a derivation performed in Liu-Wu (Arch. Ration. Mech. Anal. 233 (2019), 167--247) via an energetic variational approach.…

Analysis of PDEs · Mathematics 2022-08-02 Pierluigi Colli , Takeshi Fukao , Luca Scarpa

This paper is concerned with a diffuse interface model called as Navier-Stokes/Cahn-Hilliard system. This model is usually used to describe the motion of immiscible two-phase flow with diffusion interface. For the periodic boundary value…

Analysis of PDEs · Mathematics 2021-09-06 Yazhou Chen , Hakho Hong , Xiaoding Shi

Using basic thermodynamic principles we derive a Cahn--Hilliard--Darcy model for tumour growth including nutrient diffusion, chemotaxis, active transport, adhesion, apoptosis and proliferation. The model generalises earlier models and in…

Analysis of PDEs · Mathematics 2016-06-06 Harald Garcke , Kei Fong Lam , Emanuel Sitka , Vanessa Styles

We present a phase field model for vesicle growth or shrinkage induced by an osmotic pressure due to a chemical potential gradient. The model consists of an Allen-Cahn equation describing the evolution of phase field and a Cahn-Hilliard…

Numerical Analysis · Mathematics 2022-09-29 Xiaoxia Tang , Shuwang Li , John S. Lowengrub , Steven M. Wise

A proof of convergence is given for bulk--surface finite element semi-discretisation of the Cahn--Hilliard equation with Cahn--Hilliard-type dynamic boundary conditions in a smooth domain. The semi-discretisation is studied in the weak…

Numerical Analysis · Mathematics 2020-12-01 Paula Harder , Balázs Kovács

This paper introduces a stabilized finite element scheme for the Cahn--Hilliard cross-diffusion model, which is characterized by strongly coupled mobilities, nonlinear diffusion, and complex cross-diffusion terms. These features pose…

Numerical Analysis · Mathematics 2025-05-08 Boyi Wang , Naresh Kumar , Jinyun Yuan

We study a phase field model proposed recently in the context of tumour growth. The model couples a Cahn-Hilliard-Brinkman (CHB) system with a elliptic reaction-diffusion equation for a nutrient. The fluid velocity, governed by the Brinkman…

Analysis of PDEs · Mathematics 2019-09-06 Matthias Ebenbeck , Kei Fong Lam

In this paper, we study a phase-space analysis of a mathematical model of tumor growth with an immune response. Mathematical analysis of the model equations with multipoint initial condition, regarding to dissipativity, boundedness of…

Tissues and Organs · Quantitative Biology 2018-01-17 Veli Shakhmurov

A phase-field model for two-phase immiscible, incompressible porous media flow with surface tension effects is considered. The pore-scale model consists of a strongly coupled system of Stokes-Cahn-Hilliard equations. The fluids are…

Analysis of PDEs · Mathematics 2023-01-25 Nitu Lakhmara , Hari Shankar Mahato

In this work, we propose a new model for flow through deformable porous media, where the solid material has two phases with distinct material properties. The two phases of the porous material follow a Cahn-Hilliard type evolution, with…

Mathematical Physics · Physics 2021-09-09 Erlend Storvik , Jakub Wiktor Both , Jan Martin Nordbotten , Florin Adrian Radu

We prove existence and regularity for the solutions to a Cahn-Hilliard system describing the phenomenon of phase separation for a material contained in a bounded and regular domain. Since the first equation of the system is perturbed by the…

Analysis of PDEs · Mathematics 2020-05-05 Michele Colturato

In this work, we develop a structure-preserving numerical scheme for a Cahn-Hilliard-Darcy model that describes tumor growth in a fluid-saturated porous medium. First, we derive a physically consistent model from the general framework…

Numerical Analysis · Mathematics 2026-05-22 Daniel Acosta-Soba , Francisco Guillén-González , J. Rafael Rodríguez-Galván

We propose a new class of phase field models coupled to viscoelasticity with large deformations, obtained from a diffuse interface mixture model composed by a phase with elastic properties and a liquid phase. The model is formulated in the…

Analysis of PDEs · Mathematics 2022-04-12 Abramo Agosti , Pierluigi Colli , Harald Garcke , Elisabetta Rocca

We study the existence of weak solutions to a mixture model for tumour growth that consists of a Cahn--Hilliard--Darcy system coupled with an elliptic reaction-diffusion equation. The Darcy law gives rise to an elliptic equation for the…

Analysis of PDEs · Mathematics 2018-03-26 Harald Garcke , Kei Fong Lam
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