Related papers: Asymptotic analyses and error estimates for a Cahn…
The initial boundary value problem for a Cahn-Hilliard system subject to a dynamic boundary condition of Allen-Cahn type is treated. The vanishing of the surface diffusion on the dynamic boundary condition is the point of emphasis. By the…
We show short-time well-posedness of a diffuse interface model describing the flow of a fluid through a deformable porous medium consisting of two phases. The system non-linearly couples Biot's equations for poroelasticity, including…
We investigate the long-time dynamics and optimal control problem of a diffuse interface model that describes the growth of a tumor in presence of a nutrient and surrounded by host tissues. The state system consists of a Cahn-Hilliard type…
In this paper, we study the asymptotics of the Hahn polynomials Q_n(x; {\alpha}, {\beta}, N) as the degree n grows to infinity, when the parameters {\alpha} and {\beta} are fixed and the ratio of n/N = c is a constant in the interval (0,…
Phase-field models of tumour growth have proved useful as theoretical tools to investigate cancer invasion. A key implicit assumption underlying mathematical models of this type which have so far been proposed, though, is that cells in the…
In this paper, we study an optimal control problem for a two-dimensional Cahn-Hilliard-Darcy system with mass sources that arises in the modeling of tumor growth. The aim is to monitor the tumor fraction in a finite time interval in such a…
This article is concerned with the internal feedback stabilization of the phase field system of Cahn-Hilliard type, modeling the phase separation in a binary mixture. Under suitable assumptions on an arbitrarily fixed stationary solution,…
In this paper, we introduce an interfacial profile-preserving approach for phase field modeling for simulating incompressible two-phase flows. While the advective Cahn-Hilliard equation effectively captures the topological evolution of…
A mathematical analysis of local and nonlocal phase-field models of tumor growth is presented that includes time-dependent Darcy-Forchheimer-Brinkman models of convective velocity fields and models of long-range cell interactions. A…
The Cahn-Hilliard equation describes phase separation in binary liquids. Here we study this equation with spatially-varying sources and stirring, or advection. We specialize to symmetric mixtures and time-independent sources and discuss…
We propose a diffuse interface model to describe tumor as a multicomponent deformable porous medium. We include mechanical effects in the model by coupling the mass balance equations for the tumor species and the nutrient dynamics to a…
The recent advances in cancer immunotherapy boosted the development of tumor-immune system models aiming to provide mechanistic understanding and indicate more efficient treatment regimes. However, the complexity of such models, their…
Phase field method is playing an increasingly important role in understanding and predicting morphological evolution in materials and biological systems. Here, we develop a new analytical approach based on bifurcation analysis to explore…
In this paper, we study an optimal control problem for a nonlinear system of reaction-diffusion equations that constitutes a simplified and relaxed version of a thermodynamically consistent phase field model for tumor growth originally…
In this paper we study a distributed control problem for a phase-field system of conserved type with a possibly singular potential. We mainly handle two cases: the case of a viscous Cahn-Hilliard type dynamics for the phase variable in case…
We consider phase-field models with and without lateral flow for the numerical simulation of lateral phase separation and coarsening in lipid membranes. For the numerical solution of these models, we apply an unfitted finite element method…
In the present article we demonstrate a new hybrid model of tumor growth. Our model is stochastic by tumor population development and strongly deterministic in cell motility dynamics and spatial propagation. In addition, it has excellent…
Biomembranes and vesicles consisting of multiple phases can attain a multitude of shapes, undergoing complex shape transitions. We study a Cahn--Hilliard model on an evolving hypersurface coupled to Navier--Stokes equations on the surface…
In this work, we apply phase field simulations to examine the coarsening behavior of morphologically complex two-phase microstructures in which the phases have highly dissimilar mobilities, a condition approaching that found in experimental…
We study the sharp interface limit and well-posedness of a phase field model for self-climb of prismatic dislocation loops in periodic settings. The model is set up in a Cahn-Hilliard/Allen-Cahn framework featured with degenerate…