English
Related papers

Related papers: Asymptotic analyses and error estimates for a Cahn…

200 papers

We consider a model describing the evolution of a tumor inside a host tissue in terms of the parameters $\varphi_p$, $\varphi_d$ (proliferating and dead cells, respectively), $u$ (cell velocity) and $n$ (nutrient concentration). The…

Analysis of PDEs · Mathematics 2017-09-06 Sergio Frigeri , Kei Fong Lam , Elisabetta Rocca , Giulio Schimperna

This paper investigates an optimal control problem associated with a two-dimensional multi-species Cahn-Hilliard-Keller-Segel tumor growth model, which incorporates complex biological processes such as species diffusion, chemotaxis,…

Analysis of PDEs · Mathematics 2024-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We study a distributed optimal control problem for a nonisothermal Caginalp-type phase-field model that describes tumour growth under thermal therapy. The PDE system couples a possibly viscous Cahn-Hilliard equation, governing the evolution…

Optimization and Control · Mathematics 2026-05-05 Giulia Cavalleri , Pierluigi Colli , Elisabetta Rocca

In this paper, we consider the numerical approximations for the commonly used binary fluid-surfactant phase field model that consists two nonlinearly coupled Cahn-Hilliard equations. The main challenge in solving the system numerically is…

Numerical Analysis · Mathematics 2017-03-20 Xiaofeng Yang

We perform computer simulations of a Cahn-Hilliard model of phase separation which has dynamical asymmetry between the two coexisting phases. The dynamical asymmetry is incorporated by considering a mobility function which is order…

Soft Condensed Matter · Physics 2009-10-31 Rajeev Ahluwalia

We prove existence of weak solutions and weak-strong uniqueness for a mathematical model which couples the evolution of a phase-parameter $\varphi$ satisfying a Cahn-Hilliard type relation with the one of an additional variable $\sigma$…

Analysis of PDEs · Mathematics 2026-04-21 Robert Lasarzik , Elisabetta Rocca , Giulio Schimperna

This paper studies asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with two species of cells: proliferating cells and quiecent cells. In previous literatures it has been proved that this problem has…

Analysis of PDEs · Mathematics 2013-03-18 Shangbin Cui

A distributed optimal control problem for a diffuse interface model, which physical context is that of tumour growth dynamics, is addressed. The system we deal with comprises a Cahn--Hilliard equation for the tumour fraction coupled with a…

Analysis of PDEs · Mathematics 2021-01-20 Andrea Signori

Phase field models recently gained a lot of interest in the context of tumour growth models. Typically Darcy-type flow models are coupled to Cahn-Hilliard equations. However, often Stokes or Brinkman flows are more appropriate flow models.…

Analysis of PDEs · Mathematics 2018-07-03 Matthias Ebenbeck , Harald Garcke

We consider an optimal control problem for a diffuse interface model of tumor growth. The state equations couples a Cahn-Hilliard equation and a reaction-diffusion equation, which models the growth of a tumor in the presence of a nutrient…

Optimization and Control · Mathematics 2016-08-02 Harald Garcke , Kei-Fong Lam , Elisabetta Rocca

We construct rigorously suitable approximate solutions to the Stokes/Cahn-Hilliard system by using the method of matched asymptotics expansions. This is a main step in the proof of convergence given in the first part of this contribution,…

Analysis of PDEs · Mathematics 2021-03-31 Helmut Abels , Andreas Marquardt

We consider a differential model describing nonisothermal fast phase separation processes taking place in a three-dimensional bounded domain. This model consists of a viscous Cahn-Hilliard equation characterized by the presence of an…

Analysis of PDEs · Mathematics 2007-05-23 Maurizio Grasselli , Hana Petzeltova , Giulio Schimperna

We study an evolutionary system of Cahn-Hilliard-Darcy type including mass source and transport effects. The system may arise in a number of physical situations related to phase separation phenomena with convection, with the main and most…

Analysis of PDEs · Mathematics 2022-02-24 Giulio Schimperna

We develop a new four-phase tumor growth model with angiogenesis, derived from a diffuse-interface mixture model composed by a viable, a necrotic, a liquid and an angiogenetic component, coupled with two massless chemicals representing a…

Numerical Analysis · Mathematics 2022-03-07 Abramo Agosti , Alice Giotta Lucifero , Sabino Luzzi

In this paper we study a non-local Cahn-Hilliard equation with singular single-well potential and degenerate mobility. This results as a particular case of a more general model derived for a binary, saturated, closed and incompressible…

Analysis of PDEs · Mathematics 2023-06-29 Abramo Agosti , Elisabetta Rocca , Luca Scarpa

In this paper, we present a novel solution strategy for the Cahn-Hilliard-Biot model, a three-way coupled system that features the interplay of solid phase separation, fluid dynamics, and elastic deformations in porous media. It is a…

Numerical Analysis · Mathematics 2026-02-02 Cedric Riethmüller , Erlend Storvik

This paper investigates a Cahn-Hilliard-Swift-Hohenberg system, focusing on a three-species chemical mixture subject to physical constraints on volume fractions. The resulting system leads to complex patterns involving a separation into…

Analysis of PDEs · Mathematics 2024-10-02 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Andrea Signori

In this survey article, a variety of systems modeling tumor growth are discussed. In accordance with the hallmarks of cancer, the described models incorporate the primary characteristics of cancer evolution. Specifically, we focus on…

Dynamical Systems · Mathematics 2023-03-21 Marvin Fritz

We study an initial-boundary value problem (IBVP) for a coupled Cahn-Hilliard-Hele-Shaw system that models tumor growth. For large initial data with finite energy, we prove global (local resp.) existence, uniqueness, higher order spatial…

Analysis of PDEs · Mathematics 2012-05-31 John Lowengrub , Edriss S. Titi , Kun Zhao

In this work, we analyze a diffuse-interface model for tumor growth, subject to multiplicative white noises, posed on a bounded domain $\mathcal{O} \subset \mathbb{R}^d$, $d=2,3$. The model couples a stochastic incompressible convective…

Analysis of PDEs · Mathematics 2026-05-29 Kalpana Rawat , Kumarasamy Sakthivel