Related papers: Correction of cell-induced optical aberrations in …
We demonstrate an electro-optic wide-field method to enable fluorescence lifetime microscopy (FLIM) with high throughput and single-molecule sensitivity. Resonantly driven Pockels cells are used to efficiently gate images at 39 MHz,…
Optical coherence tomography (OCT) microscope (OCM) uses a high-numerical-aperture objective to achieve cellular-level lateral resolution. However, its practical imaging depth range is limited by the depth of focus (DOF). Although…
Radio interferometers consisting of identical antennas arranged on a regular lattice permit fast Fourier transform beamforming, which reduces the correlation cost from $\mathcal{O}(n^2)$ in the number of antennas to $\mathcal{O}(n\log n)$.…
The pyramid wavefront sensor (P-WFS) has replaced the Shack-Hartmann (SH-) WFS as sensor of choice for high performance adaptive optics (AO) systems in astronomy because of its flexibility in pupil sampling, its dynamic range, and its…
Fluorescence microscopy is an important and extensively utilised tool for imaging biological systems. However, the image resolution that can be obtained has a limit as defined through the laws of diffraction. Demand for improved resolution…
The problem of modulation classification for a multiple-antenna (MIMO) system employing orthogonal frequency division multiplexing (OFDM) is investigated under the assumption of unknown frequency-selective fading channels and…
Super-resolution microscopy is rapidly gaining importance as an analytical tool in the life sciences. A compelling feature is the ability to label biological units of interest with fluorescent markers in living cells and to observe them…
We use camera-in-the-loop calibration to calibrate a phase-only spatial light modulator (SLM) in a far-field hologram setup. The recorded intensity distributions achieve a high degree of consistency with the calculated results, indicating a…
Several telescopes include large Deformable Mirrors (DM) located directly inside the telescope. These adaptive telescopes trigger new constraints for the calibration of the Adaptive Optics (AO) systems as they usually offer no access to an…
Optical aberrations prevent telescopes from reaching their theoretical diffraction limit. Once estimated, these aberrations can be compensated for using deformable mirrors in a closed loop. Focal plane wavefront sensing enables the…
Adaptive optics in combination with multi-photon techniques is a powerful approach to image deep into a specimen. Remarkably, virtually all adaptive optics schemes today rely on wavefront modulators which are reflective, diffractive, or…
Far-field super-resolution fluorescence microscopy has been rapidly developed for applications ranging from cell biology to nanomaterials. However, it remains a significant challenge to achieve super-resolution imaging at depth in opaque…
Optical turbulence modelling and simulation are crucial for developing astronomical ground-based instruments, laser communication, laser metrology, or any application where light propagates through a turbulent medium. In the context of…
Here we report nonlinear focal modulation microscopy (NFOMM) to achieve super-resolution imaging. Abandoning the previous persistence on minimizing the size of Gaussian emission pattern by directly narrowing (e.g. Minimizing the detection…
In order to increase the corrected field of view of an adaptive optics (AO) system, several deformable mirrors (DM) have to be placed in the conjugate planes of the dominant turbulent layers (multi-conjugate adaptive optics, MCAO [Beckers…
A fluorescence correlation spectroscopy (FCS) system based on two independent measurement volumes is presented. The optical setup and data acquisition hardware are detailed, as well as a complete protocol to control the location, size and…
Aberrations limit optical systems in many situations, for example when imaging in biological tissue. Machine learning offers novel ways to improve imaging under such conditions by learning inverse models of aberrations. Learning requires…
Adaptive optics is a technique mostly used on large telescopes. It turns out to be challenging for smaller telescopes (0.5~2m) due to the small isoplanatic angle, small subapertures and high correction speeds needed at visible wavelengths,…
State-of-the-art adaptive optics (AO) systems perform non-linear Fourier-type wavefront sensing for real-time corrections of dynamic wavefront aberrations. This general class of sensors uses a filtering mask in the focal plane that converts…
Optical focusing through/inside scattering media, like multimode fiber and biological tissues, has significant impact in biomedicine yet considered challenging due to strong scattering nature of light. Previously, promising progress has…