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The Minimum Quartet Tree Cost problem is to construct an optimal weight tree from the $3{n \choose 4}$ weighted quartet topologies on $n$ objects, where optimality means that the summed weight of the embedded quartet topologies is optimal…

机器学习 · 计算机科学 2014-09-16 Rudi L. Cilibrasi , Paul M. B. Vitanyi

In this paper we offer a new perspective on the well established agglomerative clustering algorithm, focusing on recovery of hierarchical structure. We recommend a simple variant of the standard algorithm, in which clusters are merged by…

机器学习 · 统计学 2024-03-04 Annie Gray , Alexander Modell , Patrick Rubin-Delanchy , Nick Whiteley

Multiple sequence alignment is increasingly important to bioinformatics, with several applications ranging from phylogenetic analyses to domain identification. There are several ways to perform multiple sequence alignment, an important way…

计算工程、金融与科学 · 计算机科学 2015-09-14 Ravi Kumar Yadav Dega , Gunes Ercal

Understanding the evolution of a set of genes or species is a fundamental problem in evolutionary biology. The problem we study here takes as input a set of trees describing {possibly discordant} evolutionary scenarios for a given set of…

数据结构与算法 · 计算机科学 2019-07-10 Cedric Chauve , Mark Jones , Manuel Lafond , Céline Scornavacca , Mathias Weller

We consider the problem of uniformly generating a spanning tree, of a connected undirected graph. This process is useful to compute statistics, namely for phylogenetic trees. We describe a Markov chain for producing these trees. For cycle…

数据结构与算法 · 计算机科学 2020-07-08 Luís M. S. Russo , Andreia Sofia Teixeira , Alexandre P Francisco

We study the problem of constructing phylogenetic trees for a given set of species. The problem is formulated as that of finding a minimum Steiner tree on $n$ points over the Boolean hypercube of dimension $d$. It is known that an optimal…

数据结构与算法 · 计算机科学 2012-06-18 Pranjal Awasthi , Avrim Blum , Jamie Morgenstern , Or Sheffet

Given two binary trees on $N$ labeled leaves, the quartet distance between the trees is the number of disagreeing quartets. By permuting the leaves at random, the expected quartets distance between the two trees is…

组合数学 · 数学 2021-01-01 Benny Chor , Péter L. Erdős , Yonatan Komornik

A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

种群与进化 · 定量生物学 2025-09-03 S M Rafiuddin

The reconstruction of phylogenies from DNA or protein sequences is a major task of computational evolutionary biology. Common phenomena, notably variations in mutation rates across genomes and incongruences between gene lineage histories,…

概率论 · 数学 2012-11-30 Elchanan Mossel , Sebastien Roch

In recent years, Machine Learning algorithms, in particular supervised learning techniques, have been shown to be very effective in solving regression problems. We compare the performance of a newly proposed regression algorithm against…

机器学习 · 计算机科学 2023-06-16 Sabina Gooljar , Kris Manohar , Patrick Hosein

Anchor-based techniques reduce the computational complexity of spectral clustering algorithms. Although empirical tests have shown promising results, there is currently a lack of theoretical support for the anchoring approach. We define a…

机器学习 · 统计学 2020-06-30 Henry-Louis de Kergorlay , Desmond John Higham

Modelling the substitution of nucleotides along a phylogenetic tree is usually done by a hidden Markov process. This allows to define a distribution of characters at the leaves of the trees and one might be able to obtain polynomial…

种群与进化 · 定量生物学 2020-10-12 Marta Casanellas , Jesús Fernández-Sánchez , Marina Garrote-López

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

种群与进化 · 定量生物学 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

Phylogenetic trees are a central tool in understanding evolution. They are typically inferred from sequence data, and capture evolutionary relationships through time. It is essential to be able to compare trees from different data sources…

种群与进化 · 定量生物学 2017-10-31 Michelle Kendall , Caroline Colijn

The inference of phylogenetic networks, which model complex evolutionary processes including hybridization and gene flow, remains a central challenge in evolutionary biology. Until now, statistically consistent inference methods have been…

A chief problem in phylogenetics and database theory is the computation of a maximum consistent tree from a set of rooted or unrooted trees. A standard input are triplets, rooted binary trees on three leaves, or quartets, unrooted binary…

离散数学 · 计算机科学 2010-05-31 Leo van Iersel , Matthias Mnich

Phylogenetic trees canonically arise as embeddings of phylogenetic networks. We recently showed that the problem of deciding if two phylogenetic networks embed the same sets of phylogenetic trees is computationally hard, \blue{in…

组合数学 · 数学 2021-04-13 Janosch Doecker , Simone Linz , Charles Semple

We present a general setting for structure-sequence comparison in a large class of RNA structures that unifies and generalizes a number of recent works on specific families on structures. Our approach is based on tree decomposition of…

定量方法 · 定量生物学 2012-06-21 Philippe Rinaudo , Yann Ponty , Dominique Barth , Alain Denise

This paper proposes FREEtree, a tree-based method for high dimensional longitudinal data with correlated features. Popular machine learning approaches, like Random Forests, commonly used for variable selection do not perform well when there…

We give a greedy learning algorithm for reconstructing an evolutionary tree based on a certain harmonic average on triplets of terminal taxa. After the pairwise distances between terminal taxa are estimated from sequence data, the algorithm…

数据结构与算法 · 计算机科学 2007-05-23 Miklos Csuros , Ming-Yang Kao
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