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The co-occurrence of action potentials of pairs of neurons within short time intervals is known since long. Such synchronous events can appear time-locked to the behavior of an animal and also theoretical considerations argue for a…

神经元与认知 · 定量生物学 2022-05-17 Moritz Helias , Tom Tetzlaff , Markus Diesmann

Cortical activity in-vivo displays relaxational time scales much longer than the membrane time constant of the neurons or the deactivation time of ionotropic synaptic conductances. The mechanisms responsible for such slow dynamics are not…

无序系统与神经网络 · 物理学 2025-08-07 Ferdinand Tixidre , Gianluigi Mongillo , Alessandro Torcini

Large networks of sparsely coupled, excitatory and inhibitory cells occur throughout the brain. A striking feature of these networks is that they are chaotic. How does this chaos manifest in the neural code? Specifically, how variable are…

神经元与认知 · 定量生物学 2014-02-25 Guillaume Lajoie , Jean-Philippe Thivierge , Eric Shea-Brown

The functional significance of correlations between action potentials of neurons is still a matter of vivid debates. In particular it is presently unclear how much synchrony is caused by afferent synchronized events and how much is…

神经元与认知 · 定量生物学 2013-04-09 Matthias Schultze-Kraft , Markus Diesmann , Sonja Grün , Moritz Helias

Recurrent Neural Network models have elucidated the interplay between structure and dynamics in biological neural networks, particularly the emergence of irregular and rhythmic activities in cortex. However, most studies have focused on…

神经元与认知 · 定量生物学 2025-09-04 Nimrod Sherf , Xaq Pitkow , Krešimir Josić , Kevin E. Bassler

The synaptic connectivity of cortical networks features an overrepresentation of certain wiring motifs compared to simple random-network models. This structure is shaped, in part, by synaptic plasticity that promotes or suppresses…

神经元与认知 · 定量生物学 2014-12-23 Gabriel Koch Ocker , Ashok Litwin-Kumar , Brent Doiron

Complex coherent dynamics is present in a wide variety of neural systems. A typical example is the voltage transitions between up and down states observed in cortical areas in the brain. In this work, we study this phenomenon via a…

神经元与认知 · 定量生物学 2015-05-19 Jorge F. Mejias , Hilbert J. Kappen , Joaquin J. Torres

Networks of randomly connected neurons are among the most popular models in theoretical neuroscience. The connectivity between neurons in the cortex is however not fully random, the simplest and most prominent deviation from randomness…

神经元与认知 · 定量生物学 2018-07-09 Daniel Martí , Nicolas Brunel , Srdjan Ostojic

Neural activity in the brain exhibits correlated fluctuations that may strongly influence the properties of neural population coding. However, how such correlated neural fluctuations may arise from the intrinsic neural circuit dynamics and…

生物物理 · 物理学 2023-10-18 Hengyuan Ma , Yang Qi , Pulin Gong , Jie Zhang , Wenlian Lu , Jianfeng Feng

The dynamics of local cortical networks are irregular, but correlated. Dynamic excitatory--inhibitory balance is a plausible mechanism that generates such irregular activity, but it remains unclear how balance is achieved and maintained in…

神经元与认知 · 定量生物学 2020-04-28 Alan Eric Akil , Robert Rosenbaum , Krešimir Josić

Competition between synapses arises in some forms of correlation-based plasticity. Here we propose a game theory-inspired model of synaptic interactions whose dynamics is driven by competition between synapses in their weak and strong…

无序系统与神经网络 · 物理学 2011-10-19 Ajaz Ahmad Bhat , Gaurang Mahajan , Anita Mehta

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

神经元与认知 · 定量生物学 2014-03-05 Mathieu Galtier , Jonathan Touboul

Nerve impulses, the currency of information flow in the brain, are generated by an instability of the neuronal membrane potential dynamics. Neuronal circuits exhibit collective chaos that appears essential for learning, memory, sensory…

神经元与认知 · 定量生物学 2024-12-31 Rainer Engelken , Michael Monteforte , Fred Wolf

Cortical neurons are subject to sustained and irregular synaptic activity which causes important fluctuations of the membrane potential (Vm). We review here different methods to characterize this activity and its impact on spike generation.…

Learning in the brain requires complementary mechanisms: potentiation and activity-dependent homeostatic scaling. We introduce synaptic scaling to a biologically-realistic spiking model of neocortex which can learn changes in oscillatory…

神经元与认知 · 定量生物学 2013-04-09 Mark Rowan , Samuel Neymotin

Synaptic connections are known to change dynamically. High-frequency presynaptic inputs induce decrease of synaptic weights. This process is known as short-term synaptic depression. The synaptic depression controls a gain for presynaptic…

无序系统与神经网络 · 物理学 2007-05-23 Narihisa Matsumoto , Daisuke Ide , Masataka Watanabe , Masato Okada

Our mysterious brain is believed to operate near a non-equilibrium point and generate critical self-organized avalanches in neuronal activity. Recent experimental evidence has revealed significant heterogeneity in both synaptic input and…

神经元与认知 · 定量生物学 2018-07-12 Shengdun Wu , Yangsong Zhang , Yan Cui , Heng Li , Jiakang Wang , Lijun Guo , Yang Xia , Dezhong Yao , Peng Xu , Daqing Guo

The highly variable dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference but stand in apparent contrast to the deterministic response of neurons measured in vitro.…

神经元与认知 · 定量生物学 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

神经元与认知 · 定量生物学 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

We address a question on the effect of common stochastic inputs on the correlation of the spikes trains of two neurons when they are possibly nonidentical and are coupled through direct connections. We show that the change in the…

神经元与认知 · 定量生物学 2013-04-24 E. Bolhasani , Y. Azizi , A. Valizadeh
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