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Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

分子网络 · 定量生物学 2019-08-19 Thierry Emonet , Philippe Cluzel

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

种群与进化 · 定量生物学 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

Chemotaxis is the process by which cells behave in a way that follows the chemical gradient. Applications to bacteria growth, tissue inflammation, and vascular tumors provide a focus on optimization strategies. Experiments can characterize…

最优化与控制 · 数学 2007-07-18 K. Renee Fister , Maeve L. McCarthy

We discuss recent progress in the theoretical description of chemotaxis by coupling the diffusion equation of a chemical species to equations describing the motion of sensing microorganisms. In particular, we discuss models for…

软凝聚态物质 · 物理学 2019-02-05 B. Liebchen , H. Löwen

Swimming bacteria detect chemical gradients by performing temporal comparisons of recent measurements of chemical concentration. These comparisons are described quantitatively by the chemotactic response function, which we expect to…

细胞行为 · 定量生物学 2009-11-13 Damon A. Clark , Lars C. Grant

Natural bacterial habitats are often complex fluids with viscoelastic and anisotropic responses to stress; for example, they can take the form of liquid crystals (LCs), with elongated microscopic constituents that collectively align while…

Conspectus: The ability to navigate in chemical gradients, called chemotaxis, is crucial for the survival of microorganisms. It allows them to find food and to escape from toxins. Many microorganisms can produce the chemicals to which they…

软凝聚态物质 · 物理学 2018-10-03 Benno Liebchen , Hartmut Löwen

Bacterial motility, and in particular repulsion or attraction towards specific chemicals, has been a subject of investigation for over 100 years, resulting in detailed understanding of bacterial chemotaxis and the corresponding sensory…

生物物理 · 物理学 2022-06-08 Jerko Rosko , Vincent Martinez , Wilson Poon , Teuta Pilizota

In modeling the inflammatory response to a lesion in an artery wall, there are a number of chemotactic mechanisms going on within the wall layer that lead to an arterial plaque. We introduce a rather reduced model of these dynamic…

偏微分方程分析 · 数学 2015-11-10 Jonathan Bell , Animikh Biswas

Bacterial chemotaxis systems are as diverse as the environments that bacteria inhabit, but how much environmental variation can cells tolerate with a single system? Diversification of a single chemotaxis system could serve as an…

We present a new algorithm based on a Cartesian mesh for the numerical approximation of kinetic models for chemosensitive movements set in an arbitrary geometry. We investigate the influence of the geometry on the collective behavior of…

数值分析 · 数学 2013-03-12 Francis Filbet , Chang Yang

Chemotaxis is the physical phenomenon that bacteria adjust their motions according to chemical stimulus. A classical model for this phenomenon is a kinetic equation that describes the velocity jump process whose tumbling/transition kernel…

偏微分方程分析 · 数学 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

Bacteria seem masters of chemotaxis, yet recent work suggests otherwise. Henry Mattingly and colleagues (Nature Physics, 2026) argue that Escherichia coli uses only a small fraction of the sensory information available at its surface,…

细胞行为 · 定量生物学 2026-01-16 Robert G. Endres

Nematic liquid crystals confined to geometrically as well as chemically patterned substrate on one end and a flat substrate with strong anchoring on the other is studied using non-Boltzmann Monte Carlo methods. We observe significant…

软凝聚态物质 · 物理学 2010-10-18 D. Jayasri , Regina Jose , K. P. N. Murthy , V. S. S. Sastry

We propose a minimal mathematical model to explain long-range coordination of dynamics of multiple cells in epithelial spreading, which may be induced, under different conditions, by a chemical signal, or mechanical stress, or both. The…

生物物理 · 物理学 2009-11-30 L. M. Pismen , S. Y. Shvartsman

Chemotaxis describes the movement of an organism, such as single or multi-cellular organisms and bacteria, in response to a chemical stimulus. Two widely used models to describe the phenomenon are the celebrated Keller-Segel equation and a…

偏微分方程分析 · 数学 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

As motivated by studies of cellular motility driven by spatiotemporal chemotactic gradients in microdevices, we develop a framework for constructing approximate analytical solutions for the location, speed and cellular densities for cell…

偏微分方程分析 · 数学 2022-11-09 Jacobo Ayensa-Jiménez , Mohamed H. Doweidar , Manuel Doblaré , Eamonn A. Gaffney

We introduce mesoscopic and macroscopic model equations of chemotaxis with anomalous subdiffusion for modelling chemically directed transport of biological organisms in changing chemical environments with diffusion hindered by traps or…

动力系统 · 数学 2012-12-03 T. A. M. Langlands , B. I. Henry

In contexts ranging from embryonic development to bacterial ecology, cell populations migrate chemotactically along self-generated chemical gradients, often forming a propagating front. Here, we theoretically show that the stability of such…

生物物理 · 物理学 2022-06-07 Ricard Alert , Alejandro Martínez-Calvo , Sujit S. Datta

The signaling apparatus mediating bacterial chemotaxis can adapt to a wide range of persistent external stimuli. In many cases, the bacterial activity returns to its pre-stimulus level exactly and this "perfect adaptability" is robust…

生物物理 · 物理学 2017-10-16 Bernardo A. Mello , Yuhai Tu