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Zebrafish pretectal neurons exhibit specificities for large-field optic flow patterns associated with rotatory or translatory body motion. We investigate the hypothesis that these specificities reflect the input statistics of natural optic…

The tracing of neural pathways through large volumes of image data is an incredibly tedious and time-consuming process that significantly encumbers progress in neuroscience. We are exploring deep learning's potential to automate…

计算机视觉与模式识别 · 计算机科学 2018-09-05 Ishtar Nyawira , Kristi Bushman , Iris Qian , Annie Zhang

Zebrafish are a common model organism used to identify new disease therapeutics. High-throughput drug screens can be performed on larval zebrafish in multi-well plates by observing changes in behaviour following a treatment. Analysis of…

定量方法 · 定量生物学 2022-11-09 Christopher Fusco , Angel Allen

Larval zebrafish hunting provides a tractable setting to study how ecological and energetic constraints shape adaptive behavior in both biological brains and artificial agents. Here we develop a minimal agent-based model, training recurrent…

神经元与认知 · 定量生物学 2025-10-07 Raaghav Malik , Satpreet H. Singh , Sonja Johnson-Yu , Nathan Wu , Roy Harpaz , Florian Engert , Kanaka Rajan

The origins of spontaneous movements have been investigated in human as well as in other vertebrates. Studies have reported an increase in neuronal activity one second before the onset of a given movement: this is known as readiness…

神经元与认知 · 定量生物学 2020-12-22 Selma Mehyaoui

Neural dynamics underlie behaviors from memory to sleep, yet identifying mechanisms for higher-order phenomena (e.g., social interaction) is experimentally challenging. Existing whole-brain models often fail to scale to single-neuron…

神经元与认知 · 定量生物学 2025-11-03 Sam Fatehmanesh Vegas , Matt Thomson , James Gornet , David Prober

Collective movements are pervasive behaviours among social organisms and have led to the development of many models. However, modelling animal trajectories and social interactions in simple bounded environments remains a challenge.…

神经元与认知 · 定量生物学 2018-11-28 Leo Cazenille , Nicolas Bredeche , José Halloy

Data-driven benchmarks have led to significant progress in key scientific modeling domains including weather and structural biology. Here, we introduce the Zebrafish Activity Prediction Benchmark (ZAPBench) to measure progress on the…

In this report, we introduce a novel self-supervised learning method for extracting latent embeddings from behaviors of larval zebrafish. Drawing inspiration from Masked Modeling techniquesutilized in image processing with Masked…

计算机视觉与模式识别 · 计算机科学 2024-03-26 Lanxin Xu , Shuo Wang

Oscillatory dynamics of complex networks has recently attracted great attention. In this paper we study pattern formation in oscillatory complex networks consisting of excitable nodes. We find that there exist a few center nodes and small…

混沌动力学 · 物理学 2011-11-23 Liao Xuhong , Xia Qinzhi , Qian Yu , Zhang Lisheng , Hu Gang , Mi Yuanyuan

Most living organisms show highly conserved physiological changes following a 24-hour cycle which goes by the name of circadian rhythm. Among experimental models, the effects of light-dark cycle have been recently investigated in the larval…

Epileptic seizures are characterised by abnormal brain dynamics at multiple scales, engaging single neurons, neuronal ensembles and coarse brain regions. Key to understanding the cause of such emergent population dynamics, is capturing the…

神经元与认知 · 定量生物学 2022-12-13 Dominic RW Burrows

Rhythmic and sequential segmentation of the embryonic body plan is a vital developmental patterning process in all vertebrate species. However, a theoretical framework capturing the emergence of dynamic patterns of gene expression from the…

生物物理 · 物理学 2016-10-12 David J. Jörg , Andrew C. Oates , Frank Jülicher

Accurate decoding of neural spike trains and relating them to motor output is a challenging task due to the inherent sparsity and length in neural spikes and the complexity of brain circuits. This master project investigates experimental…

神经元与认知 · 定量生物学 2025-02-13 Fei Gao

Collective motion is one of the most ubiquitous behaviours displayed by social organisms and has led to the development of numerous models. Recent advances in the understanding of sensory system and information processing by animals impel…

生物物理 · 物理学 2016-01-28 Bertrand Collignon , Axel Séguret , José Halloy

An effective evasion strategy allows prey to survive encounters with predators. Prey are generally thought to escape in a direction that is either random or serves to maximize the minimum distance from the predator. Here we introduce a…

定量方法 · 定量生物学 2023-02-22 Yusheng Jiao , Brendan Colvert , Yi Man , Matthew J. McHenry , Eva Kanso

The recent development of genetically encoded calcium indicators enables monitoring in vivo the activity of neuronal populations. Most analysis of these calcium transients relies on linear regression analysis based on the sensory stimulus…

神经元与认知 · 定量生物学 2014-09-10 Fabrizio De Vico Fallani , Martina Corazzol , Jenna R. Sternberg , Claire Wyart , Mario Chavez

Brain activity is characterized by brain-wide spatiotemporal patterns which emerge from synapse-mediated interactions between individual neurons. Calcium imaging provides access to in vivo recordings of whole-brain activity at single-neuron…

神经元与认知 · 定量生物学 2023-09-13 Richard E. Rosch , Dominic R. W. Burrows , Christopher W. Lynn , Arian Ashourvan

Sensory perception (e.g. vision) relies on a hierarchy of cortical areas, in which neural activity propagates in both directions, to convey information not only about sensory inputs but also about cognitive states, expectations and…

神经元与认知 · 定量生物学 2023-04-13 Grégory Faye , Guilhem Fouilhé , Rufin VanRullen

An inverse procedure is developed and tested to recover functional and structural information from global signals of brains activity. The method assumes a leaky-integrate and fire model with excitatory and inhibitory neurons, coupled via a…

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