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Improvements in technique in conjunction with an evolution of the theoretical and conceptual approach to neuronal networks provide a new perspective on living neurons in culture. Organization and connectivity are being measured…

无序系统与神经网络 · 物理学 2010-08-02 Jean-Pierre Eckmann , Ofer Feinerman , Leor Gruendlinger , Elisha Moses , Jordi Soriano , Tsvi Tlusty

We study neural connectivity in cultures of rat hippocampal neurons. We measure the neurons' response to an electric stimulation for gradual lower connectivity, and characterize the size of the giant cluster in the network. The connectivity…

神经元与认知 · 定量生物学 2010-07-30 Jordi Soriano , Ilan Breskin , Elisha Moses , Tsvi Tlusty

We study living neural networks by measuring the neurons' response to a global electrical stimulation. Neural connectivity is lowered by reducing the synaptic strength, chemically blocking neurotransmitter receptors. We use a…

神经元与认知 · 定量生物学 2010-07-30 Ilan Breskin , Jordi Soriano , Elisha Moses , Tsvi Tlusty

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

神经元与认知 · 定量生物学 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

How far is neuroepithelial cell proliferation in the developing central nervous system a deterministic process? Or, to put it in a more precise way, how accurately can it be described by a deterministic mathematical model? To provide tracks…

偏微分方程分析 · 数学 2010-05-04 Jean Clairambault , Vladimir Flores , Benoit Perthame , Melina Rapacioli , Edmundo Rofman , Rafael Verdes

It is becoming increasingly appreciated that the signal transduction systems used by eukaryotic cells to achieve a variety of essential responses represent highly complex networks rather than simple linear pathways. While significant effort…

Neural development represents not only an exciting and complex field of study, with ongoing progress, but it also became the epicentre of neuroscience and developmental biology, as it strives to describe the underlying cellular and…

神经元与认知 · 定量生物学 2014-05-15 Ana M. Mihut , Graham Morgan , Marcus Kaiser

The principles of neural encoding and computations are inherently collective and usually involve large populations of interacting neurons with highly correlated activities. While theories of neural function have long recognized the…

神经元与认知 · 定量生物学 2019-05-14 Christophe Gardella , Olivier Marre , Thierry Mora

The formation of neuron networks is a process of fundamental importance for understanding the development of the nervous system and for creating biomimetic devices for tissue engineering and neural repair. The basic process that controls…

细胞行为 · 定量生物学 2022-05-16 Ilya Yurchenko , Matthew Farwell , Donovan D. Brady , Cristian Staii

Deep neural networks exhibit empirical neural scaling laws, with error decreasing as a power law with increasing model or data size, across a wide variety of architectures, tasks, and datasets. This universality suggests that scaling laws…

机器学习 · 计算机科学 2024-12-12 Ari Brill

We study the dynamics of proliferating cell collectives whose microscopic constituents' growth is inhibited by macroscopic growth-induced stress. Discrete particle simulations of a growing collective show the emergence of concentric-ring…

生物物理 · 物理学 2024-05-17 Scott Weady , Bryce Palmer , Adam Lamson , Taeyoon Kim , Reza Farhadifar , Michael J. Shelley

The spontaneous formation and subsequent growth, dissolution, merger and competition of social groups bears similarities to physical phase transitions in metastable finite systems. We examine three different scenarios, percolation, spinodal…

物理与社会 · 物理学 2022-09-22 Frank Schweitzer , Georges Andres

The study of neuronal morphology is important not only for its potential relationship with neuronal dynamics, but also as a means to classify diverse types of cells and compare than among species, organs, and conditions. In the present…

神经元与认知 · 定量生物学 2024-03-11 Alexandre Benatti , Henrique F. de Arruda , Luciano da F. Costa

Artificial Intelligence has looked into biological systems as a source of inspiration. Although there are many aspects of the brain yet to be discovered, neuroscience has found evidence that the connections between neurons continuously grow…

神经与进化计算 · 计算机科学 2020-10-29 Javier Lopez Randulfe , Leon Bonde Larsen

Percolation, the formation of a macroscopic connected component, is a key feature in the description of complex networks. The dynamical properties of a variety of systems can be understood in terms of percolation, including the robustness…

统计力学 · 物理学 2013-06-24 Shane Squires , Katherine Sytwu , Diego Alcala , Thomas Antonsen , Edward Ott , Michelle Girvan

Biological nervous systems are created in a fundamentally different way than current artificial neural networks. Despite its impressive results in a variety of different domains, deep learning often requires considerable engineering effort…

神经与进化计算 · 计算机科学 2023-07-18 Elias Najarro , Shyam Sudhakaran , Sebastian Risi

Many random growth models have the property that the set of discovered sites, scaled properly, converges to some deterministic set as time grows. Such results are known as shape theorems. Typically, not much is known about the shapes. For…

机器学习 · 统计学 2020-06-26 Sebastian Rosengren

Synaptic plasticity allows cortical circuits to learn new tasks and to adapt to changing environments. How do cortical circuits use plasticity to acquire functions such as decision-making or working memory? Neurons are connected in complex…

神经元与认知 · 定量生物学 2023-03-08 Néstor Parga , Luis Serrano-Fernández , Joan Falcó-Roget

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

神经元与认知 · 定量生物学 2020-12-02 Hui Wei

We introduce a novel approach for the quantitative assessment of the connectivity in neuronal cultures, based on the statistical mechanics of percolation on a graph. This allows us to follow the development of the culture and see the…

无序系统与神经网络 · 物理学 2010-08-03 Jordi Soriano , Maria Rodrriguez Martinez , Tsvi Tlusty , Elisha Moses
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