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A healthy human brain is perfused with blood flowing laminarly through cerebral vessels, providing brain tissue with substrates such as oxygen and glucose. Under normal conditions, cerebral blood flow is controlled by autoregulation as well…

Cerebral arterial blood flow (CABF) can be investigated in few seconds without any synchronization by Real-Time phase contrast. Significant changes in CABF were found between expiration and inspiration during normal breathing of healthy…

Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events;…

Heart rate variability (HRV), defined as the variability between consecutive heartbeats, is a surrogate measure of cardiac vagal tone. It is widely accepted that a decreased HRV is associated to several risk factors and cardiovascular…

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and sustained hypertension is an often silent risk factor, making cuffless continuous blood pressure (BP) monitoring with wearable devices important for…

Pulse transit time (PTT) has been widely used for cuffless blood pressure (BP) measurement. But, it requires more than one cardiovascular signals involving more than one sensing device. In this paper, we propose a method for continuous…

This paper presents a novel blood pressure (BP) estimation method based on pulse transit time (PTT) and pulse arrival time (PAT) to estimate the systolic BP (SBP) and the diastolic BP (DBP). A data acquisition hardware is designed for…

Blood pressure (BP) changes are linked to individual health status in both clinical and non-clinical settings. This study developed a deep learning model to classify systolic (SBP), diastolic (DBP), and mean (MBP) BP changes using…

Using a three-compartment model of blood pressure dynamics, we analyze theoretically the short term cardiovascular variability: how the respiratory-related blood pressure fluctuations are buffered by appropriate heart rate changes: i.e. the…

Blood Pressure (BP) and Heart Rate (HR) provide information on clin-ical condition along 24h. Both signals present circadian changes due to sympa-thetic/parasympathetic control system that influence the relationship between them. Moreover,…

Accurate and continuous blood pressure (BP) monitoring is essential to the early prevention of cardiovascular diseases. Non-invasive and cuff-less BP estimation algorithm has gained much attention in recent years. Previous studies have…

The clinical and economic burden of cardiovascular diseases (CVDs) poses a global challenge. Growing evidence suggests an early assessment of arterial stiffness can provide insights into the pathogenesis of CVDs. However, it remains…

It is shown that the dependence of the cerebral blood flow (CBF) on mean arterial blood pressure (MABP) can be described with a simple model having the following assumptions. Below certain MABP (denoted as MABP1) there are no autoregulatory…

Prenatal maternal stress alters maternal-fetal heart rate coupling, as demonstrated by the Fetal Stress Index derived from bivariate phase-rectified signal averaging. Here, we extend this framework using information-theoretical measures to…

Dynamic cerebral autoregulation, that is the transient response of cerebral blood flow to changes in arterial blood pressure, is currently assessed using a variety of different time series methods and data collection protocols. In the…

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

The average wavelet coefficient method is applied to investigate the scaling features of heart rate variability during meditation, a state of induced mental relaxation. While periodicity dominates the behavior of the heart rate time series…

Aims. Clinical data indicating a heart rate (HR) target during rate control therapy for permanent atrial fibrillation (AF) and assessing its eventual relationship with reduced exercise tolerance are lacking. The present study aims at…

The use of office measurement of Blood Pressure (BP) as well as of the mean on day-time, on night-time or on 24h does not accurately describe the changes of the BP circadian rhythm. Moreover, several risk factors affect this rhythm but…

Efficient management of low blood pressure (BP) in preterm neonates remains challenging with a considerable variability in clinical practice. The ability to assess preterm wellbeing during episodes of low BP will help to decide when and…